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The map label for this gene is dnaQ [H]

Identifier: 88606785

GI number: 88606785

Start: 775329

End: 776063

Strand: Reverse

Name: dnaQ [H]

Synonym: APH_0730

Alternate gene names: 88606785

Gene position: 776063-775329 (Counterclockwise)

Preceding gene: 88607823

Following gene: 88606861

Centisome position: 52.75

GC content: 42.45

Gene sequence:

>735_bases
ATGAAGGTTAGAGAGATTGTTTTAGATACGGAAACAACTGGCCTTGATGCTGATGGTGGCGACAGAATAATAGAGATAGG
GTGCGTTGAGCTAGTAGATTATGTTATGACTGGTCGTGTGTTTCATAAATACATAGATCCAGAGCGTGATATATCTGTAG
CTGCGACTAGGGTGCACGGAATAACAAGAGAATCTCTTATAGGAATGCCGAAGTTTGCTGAAGTTGCAGATGAGCTCCTA
GATTTTCTTCAGGACAGTGCTCTCGTTATACATAATGCAAGATTCGACATGAGGTTTCTCGAGGTTGAGATTGAGCGCTT
AAGCAATAAGCGGGCCATTACTAATACTATTGTCGATACTCTCGAGATGGCGAGAAAAAAGTTTCCGGGGATGCCGGCTA
GTTTGGATGCGCTGTGTAAGAGGTTTAACATATCGACGCAAGAGAGGAAATTTCACGGAGCATTGAAGGATGCCACATTG
CTGGCGCGAGTGTATGTAGAGCTGTTAGAAGCGCTGCAAAGGAGGCTAGTGTTTTCTCAAGAGGGAGATGACAGCAAGCA
GGTTTCTGTAATCCATGATAAAGCAAAAAGAGTTGTATATCCTGCGCGCACATTTACATTGAGCTCTGAAGAGAAGAGGC
TGCACAGGCAAACTGTTAGTAAGATGAAAAATCCTATATGGCTCATGTGTTTTGATGAAAAAGAGTTTTTCTGTAATGAA
AACATTAACTCGTAA

Upstream 100 bases:

>100_bases
GCGTGCGTGAATGCTCCCGTTGTACAGATAAATGATGACTATTACGAAAATCTAGATGCGGAATCTATGGAGAAGATTTT
GCTGAAATTAAAGGAGGGCA

Downstream 100 bases:

>100_bases
TCCTATAGAATCCGCACTCACCAGTAATGCAAGCATATAAGCATAATGAGTTTGTTTTACCATGGAGCAATGAAGAGAAG
AGGTAGCACATAGACTAACT

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MKVREIVLDTETTGLDADGGDRIIEIGCVELVDYVMTGRVFHKYIDPERDISVAATRVHGITRESLIGMPKFAEVADELL
DFLQDSALVIHNARFDMRFLEVEIERLSNKRAITNTIVDTLEMARKKFPGMPASLDALCKRFNISTQERKFHGALKDATL
LARVYVELLEALQRRLVFSQEGDDSKQVSVIHDKAKRVVYPARTFTLSSEEKRLHRQTVSKMKNPIWLMCFDEKEFFCNE
NINS

Sequences:

>Translated_244_residues
MKVREIVLDTETTGLDADGGDRIIEIGCVELVDYVMTGRVFHKYIDPERDISVAATRVHGITRESLIGMPKFAEVADELL
DFLQDSALVIHNARFDMRFLEVEIERLSNKRAITNTIVDTLEMARKKFPGMPASLDALCKRFNISTQERKFHGALKDATL
LARVYVELLEALQRRLVFSQEGDDSKQVSVIHDKAKRVVYPARTFTLSSEEKRLHRQTVSKMKNPIWLMCFDEKEFFCNE
NINS
>Mature_244_residues
MKVREIVLDTETTGLDADGGDRIIEIGCVELVDYVMTGRVFHKYIDPERDISVAATRVHGITRESLIGMPKFAEVADELL
DFLQDSALVIHNARFDMRFLEVEIERLSNKRAITNTIVDTLEMARKKFPGMPASLDALCKRFNISTQERKFHGALKDATL
LARVYVELLEALQRRLVFSQEGDDSKQVSVIHDKAKRVVYPARTFTLSSEEKRLHRQTVSKMKNPIWLMCFDEKEFFCNE
NINS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=191, Percent_Identity=46.5968586387435, Blast_Score=165, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 28000; Mature: 28000

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVREIVLDTETTGLDADGGDRIIEIGCVELVDYVMTGRVFHKYIDPERDISVAATRVHG
CCCHHEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
ITRESLIGMPKFAEVADELLDFLQDSALVIHNARFDMRFLEVEIERLSNKRAITNTIVDT
CCHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHH
LEMARKKFPGMPASLDALCKRFNISTQERKFHGALKDATLLARVYVELLEALQRRLVFSQ
HHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGDDSKQVSVIHDKAKRVVYPARTFTLSSEEKRLHRQTVSKMKNPIWLMCFDEKEFFCNE
CCCCCHHHHHHHHHHHHEEECCCEEEECHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCC
NINS
CCCC
>Mature Secondary Structure
MKVREIVLDTETTGLDADGGDRIIEIGCVELVDYVMTGRVFHKYIDPERDISVAATRVHG
CCCHHEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
ITRESLIGMPKFAEVADELLDFLQDSALVIHNARFDMRFLEVEIERLSNKRAITNTIVDT
CCHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHH
LEMARKKFPGMPASLDALCKRFNISTQERKFHGALKDATLLARVYVELLEALQRRLVFSQ
HHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGDDSKQVSVIHDKAKRVVYPARTFTLSSEEKRLHRQTVSKMKNPIWLMCFDEKEFFCNE
CCCCCHHHHHHHHHHHHEEECCCEEEECHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCC
NINS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA