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The map label for this gene is 88606724

Identifier: 88606724

GI number: 88606724

Start: 1434552

End: 1435424

Strand: Reverse

Name: 88606724

Synonym: APH_1371

Alternate gene names: NA

Gene position: 1435424-1434552 (Counterclockwise)

Preceding gene: 88607030

Following gene: 88607954

Centisome position: 97.56

GC content: 42.84

Gene sequence:

>873_bases
ATGACAGACGAACATAATAAACCCAATGTCGAAGATATTAAAATGTTCGCGGAGGTCTTGAGGTTTTATCATGATAGCGG
GGTAACACATACGCTAAACGATGACCTGCACCCAGATGATACTTTAAGTCCTGCAAATTTTGAAAAATCTCCCGTCGTAC
CTGACCGCGCAAAAACCCGTGAGTCTCAAGAGATCGTCCTGAATAAAACAAGTAACAAGAAGAGCTCTTCCAATGCCAAT
ATGCTTCAATGGGTGGAAGAAGCAAGAAAGGCAGCTGCTAACTGTGTAGATTTGGCTGAGCTGAGAGCTGCTGTATGTGC
ATTTGAAGGATGTGAGATAAAAAAAGCAGCTGTGAACACCGTTTTCTCCGATGGTAACCCAAAATCTAAGATTATGTTGA
TAGGAGAAGCCCCTGGAAGTACGGAAGATAGAGAAGGTATACCATTTTGTGGAGCCAGTGGACAATTGCTTGATAAAATG
TTTGCAGCCATTAATCTAAATCGCTCATCAAACATCTATATAAGTAATACTGTGTTCTGGCGCCCACCAGGCAATCGCAA
ACCCACAGATTTTGAGCTAGAAGTGTGTAGACCATTTGTGGAGAAACACATATCGTTAGTGGATCCAGATGTAGTCGTAA
TGGTAGGTAGCACAGCGTGTTATTCACTGCTGCAAACGCCTGACAATATTTCACGACTCAGAGGAAAGTTCTATGAATAT
ACAAATAGCTTCCTCTCCCGTTCCATAACTGCAATGGTCATATTTCACCCGGCATATCTCCTGAGACAGCCTCAGCAAAA
ACGGCTTGCCTGGGAAGATTTGAAGATGTTGCGCGCCTATATCGAAACACACAAAATTCAGGTGAATACCTAG

Upstream 100 bases:

>100_bases
CAGAGGAGTGACAGTCTCATCAGGAAACGCTCTTACCAACCTGTTTTCTGGGGTATACCTCTACTGAGCCGAGGTGGTAT
CTTACAATCCGTGTACGGCT

Downstream 100 bases:

>100_bases
AGTACTTGTAGGGCGTTTCTTGTTGTTAAATATGCACTTACAAATTTAAGCAACAAGTTGTACCTTATAATACGCTACTG
TTAAGGAGTTTATTGCTATC

Product: uracil-DNA glycosylase

Products: diphosphate; DNAn+1

Alternate protein names: Uracil-DNA Glycosylase; Phage SPO1 DNA Polymerase-Like Protein; DNA Polymerase; Uracil DNA Glycosylase Superfamily Protein; DNA Polymerase Bacteriophage-Type; DNA-Directed DNA Polymerase; DNA Polymerase-Related Protein; DNA Polymerase-Related Protein Bacteriophage-Type; DNA Glycosylase; Phage Spo1 DNA Polymerase-Related Protein; Bacteriophage-Related DNA Polymerase; N-Terminus Of Bacteriophage-Type DNA Polymerase; Phage DNA Polymerase; Uracil-DNA Glycosylase C-Terminal Domain Protein; Bacteriophage-Type DNA Polymerase N-Terminal Domain Protein; DNA Polymerase Bacteriophage-Type Protein; Phage SPO1 DNA Polymerase Domain-Containing Protein; DNA Polymerase Domain-Containing Protein; Phage Related DNA Polymerase; Uracil-DNA Glycosylase C-Terminal; Phage SpO1 DNA Polymerase-Related Protein; Uracil-DNA Glycosylase Family 4 Protein; Arginine Biosynthesis Bifunctional Protein ArgJ; Bacteriophage-Type DNA Polymerase; DNA Polymerase Related Protein; DNA-Directed DNA Polymerase Bacteriophage-Type; Uracil DNA Glycosylase Superfamily; Uracil-DNA Glycosylase Phage-Related Protein; Phage Shock Protein E; Phage Spo1 DNA Polymerase Domain Protein; Uracil-DNA Glycosylase-Like Protein; Uracil-DNA Glycosylase-Related Protein

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTDEHNKPNVEDIKMFAEVLRFYHDSGVTHTLNDDLHPDDTLSPANFEKSPVVPDRAKTRESQEIVLNKTSNKKSSSNAN
MLQWVEEARKAAANCVDLAELRAAVCAFEGCEIKKAAVNTVFSDGNPKSKIMLIGEAPGSTEDREGIPFCGASGQLLDKM
FAAINLNRSSNIYISNTVFWRPPGNRKPTDFELEVCRPFVEKHISLVDPDVVVMVGSTACYSLLQTPDNISRLRGKFYEY
TNSFLSRSITAMVIFHPAYLLRQPQQKRLAWEDLKMLRAYIETHKIQVNT

Sequences:

>Translated_290_residues
MTDEHNKPNVEDIKMFAEVLRFYHDSGVTHTLNDDLHPDDTLSPANFEKSPVVPDRAKTRESQEIVLNKTSNKKSSSNAN
MLQWVEEARKAAANCVDLAELRAAVCAFEGCEIKKAAVNTVFSDGNPKSKIMLIGEAPGSTEDREGIPFCGASGQLLDKM
FAAINLNRSSNIYISNTVFWRPPGNRKPTDFELEVCRPFVEKHISLVDPDVVVMVGSTACYSLLQTPDNISRLRGKFYEY
TNSFLSRSITAMVIFHPAYLLRQPQQKRLAWEDLKMLRAYIETHKIQVNT
>Mature_289_residues
TDEHNKPNVEDIKMFAEVLRFYHDSGVTHTLNDDLHPDDTLSPANFEKSPVVPDRAKTRESQEIVLNKTSNKKSSSNANM
LQWVEEARKAAANCVDLAELRAAVCAFEGCEIKKAAVNTVFSDGNPKSKIMLIGEAPGSTEDREGIPFCGASGQLLDKMF
AAINLNRSSNIYISNTVFWRPPGNRKPTDFELEVCRPFVEKHISLVDPDVVVMVGSTACYSLLQTPDNISRLRGKFYEYT
NSFLSRSITAMVIFHPAYLLRQPQQKRLAWEDLKMLRAYIETHKIQVNT

Specific function: Unknown

COG id: COG1573

COG function: function code L; Uracil-DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 32658; Mature: 32527

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDEHNKPNVEDIKMFAEVLRFYHDSGVTHTLNDDLHPDDTLSPANFEKSPVVPDRAKTR
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCC
ESQEIVLNKTSNKKSSSNANMLQWVEEARKAAANCVDLAELRAAVCAFEGCEIKKAAVNT
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VFSDGNPKSKIMLIGEAPGSTEDREGIPFCGASGQLLDKMFAAINLNRSSNIYISNTVFW
HHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEE
RPPGNRKPTDFELEVCRPFVEKHISLVDPDVVVMVGSTACYSLLQTPDNISRLRGKFYEY
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCHHHHHHHHHHHHH
TNSFLSRSITAMVIFHPAYLLRQPQQKRLAWEDLKMLRAYIETHKIQVNT
HHHHHHHHHHHHHEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHCEEEECC
>Mature Secondary Structure 
TDEHNKPNVEDIKMFAEVLRFYHDSGVTHTLNDDLHPDDTLSPANFEKSPVVPDRAKTR
CCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCC
ESQEIVLNKTSNKKSSSNANMLQWVEEARKAAANCVDLAELRAAVCAFEGCEIKKAAVNT
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VFSDGNPKSKIMLIGEAPGSTEDREGIPFCGASGQLLDKMFAAINLNRSSNIYISNTVFW
HHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEE
RPPGNRKPTDFELEVCRPFVEKHISLVDPDVVVMVGSTACYSLLQTPDNISRLRGKFYEY
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCHHHHHHHHHHHHH
TNSFLSRSITAMVIFHPAYLLRQPQQKRLAWEDLKMLRAYIETHKIQVNT
HHHHHHHHHHHHHEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA