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The map label for this gene is comF [H]

Identifier: 88606693

GI number: 88606693

Start: 1370562

End: 1371215

Strand: Reverse

Name: comF [H]

Synonym: APH_1303

Alternate gene names: 88606693

Gene position: 1371215-1370562 (Counterclockwise)

Preceding gene: 88607238

Following gene: 88607427

Centisome position: 93.2

GC content: 39.76

Gene sequence:

>654_bases
GTGAATTGTGGAATTTACACAGTAAGGGATGCGGCATTATGCGTTTCCTGTATAAACAATATAAAATTTTTACAGGGCTA
TTTCTGTATAAAATGTGGGAAGAATTTAGAACAAAACGCCGGCGTATGCGTAAGATGCACAGCATTTAATTCACATCTTT
CAGCACTGGAGTCTGTGTTTGAGTACGATAATACAAGTAAGCACATGGTTTTACAGTTCAAATTTTATGGTGATATATCA
AACATTAAAACTTACGCGGGTTGGATGTTTGAAAAGGGAAAGGAGTTGCTTGCAAGAGCAGAGCTAATAGTCCCGGTTCC
TATGCATTGTATGCGGTTACGGCGACGCAAGTACAATCAATCTGTGTTATTGGCACGGGCTTTGAGTAAACTTTGCGGAA
TCCCGTTGGAAGTTTTTACACTGAAAAAAGCAAAAAATACTACTCCTCAGAGTTATTTATCGGCTTCAAAGCGGTCAAAG
AATGTTTGGAACTCTTTTAAAGTGACAAATTCCGTGCTTTTTAGAGGCAAAGTGGTTGTACTTATAGATGACGTTGTAAC
TACAGGGGCATCACTTCAAGAATGTGCGCGAGTCCTTAAGAACTCCGGGGCTAAAGAAGTTCTTGGCCTCACTCTTGCTA
GAACGATGTCATAA

Upstream 100 bases:

>100_bases
GTCCTTTTGCAGTTTTGTGAAGCGCTGCTACTGCCGTGTAGGCTGTATATTGAGAACTACTGCTCAGAAGTTTATTGAGG
TTTTTTTTCCGCGTTCTTGT

Downstream 100 bases:

>100_bases
ATAATAAATAAAAGAGAAAACGCCTGTAGTTATTTAATAGTCTTCGTTTCCGTTCCGCAGATAGATGTTTTGACTTCCAA
CTCTGTGGATCGTAAGTCAT

Product: comF family protein

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNCGIYTVRDAALCVSCINNIKFLQGYFCIKCGKNLEQNAGVCVRCTAFNSHLSALESVFEYDNTSKHMVLQFKFYGDIS
NIKTYAGWMFEKGKELLARAELIVPVPMHCMRLRRRKYNQSVLLARALSKLCGIPLEVFTLKKAKNTTPQSYLSASKRSK
NVWNSFKVTNSVLFRGKVVVLIDDVVTTGASLQECARVLKNSGAKEVLGLTLARTMS

Sequences:

>Translated_217_residues
MNCGIYTVRDAALCVSCINNIKFLQGYFCIKCGKNLEQNAGVCVRCTAFNSHLSALESVFEYDNTSKHMVLQFKFYGDIS
NIKTYAGWMFEKGKELLARAELIVPVPMHCMRLRRRKYNQSVLLARALSKLCGIPLEVFTLKKAKNTTPQSYLSASKRSK
NVWNSFKVTNSVLFRGKVVVLIDDVVTTGASLQECARVLKNSGAKEVLGLTLARTMS
>Mature_217_residues
MNCGIYTVRDAALCVSCINNIKFLQGYFCIKCGKNLEQNAGVCVRCTAFNSHLSALESVFEYDNTSKHMVLQFKFYGDIS
NIKTYAGWMFEKGKELLARAELIVPVPMHCMRLRRRKYNQSVLLARALSKLCGIPLEVFTLKKAKNTTPQSYLSASKRSK
NVWNSFKVTNSVLFRGKVVVLIDDVVTTGASLQECARVLKNSGAKEVLGLTLARTMS

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=194, Percent_Identity=28.3505154639175, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 24269; Mature: 24269

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCGIYTVRDAALCVSCINNIKFLQGYFCIKCGKNLEQNAGVCVRCTAFNSHLSALESVF
CCCCEEEHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHH
EYDNTSKHMVLQFKFYGDISNIKTYAGWMFEKGKELLARAELIVPVPMHCMRLRRRKYNQ
HCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCH
SVLLARALSKLCGIPLEVFTLKKAKNTTPQSYLSASKRSKNVWNSFKVTNSVLFRGKVVV
HHHHHHHHHHHHCCCHHEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LIDDVVTTGASLQECARVLKNSGAKEVLGLTLARTMS
EEECHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNCGIYTVRDAALCVSCINNIKFLQGYFCIKCGKNLEQNAGVCVRCTAFNSHLSALESVF
CCCCEEEHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHHH
EYDNTSKHMVLQFKFYGDISNIKTYAGWMFEKGKELLARAELIVPVPMHCMRLRRRKYNQ
HCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCH
SVLLARALSKLCGIPLEVFTLKKAKNTTPQSYLSASKRSKNVWNSFKVTNSVLFRGKVVV
HHHHHHHHHHHHCCCHHEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LIDDVVTTGASLQECARVLKNSGAKEVLGLTLARTMS
EEECHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]