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The map label for this gene is ydgK [H]

Identifier: 88196274

GI number: 88196274

Start: 2420613

End: 2421551

Strand: Reverse

Name: ydgK [H]

Synonym: SAOUHSC_02633

Alternate gene names: 88196274

Gene position: 2421551-2420613 (Counterclockwise)

Preceding gene: 88196275

Following gene: 88196273

Centisome position: 85.83

GC content: 33.97

Gene sequence:

>939_bases
ATGAATGATTTAACGCATTTTAACAAGCGTTCACCGATATTTATTATTATTTTAGGATCTTTGACGGCCATTGGAGCATT
ATCGATAGATATGTTTTTGCCTGGATTACCAGATATTAGACATGATTTTCAAACAACGACGTCTAACGCACAATTAACAT
TATCGATGTTTATGATTGGTTTAGCGTTTGGTAATTTGTTTGCTGGTCCAATTTCAGATTCAACTGGGCGCAGAAAGCCG
CTTATTATAGCTATGATTATTTTTACATTAGCAAGTTTAGGTATTGTTTTTGTACATAATATTTGGCTGATGGTTGCATT
AAGATTTCTTCAAGGAGTGACAGGTGGCGCAGCAGCAGTTATTTCAAGAGCTATAGCAAGTGATATGTATAGTGGTAATG
AACTAACTAAGTTTATGGCATTATTGATGCTTGTTAATGGTATTGCACCAGTTGTTGCGCCAACAATAGGGGGCATAATT
TTAAATTATTCTGTCTGGCGTATGGTCTTTGTCATTCTGACTATCTTTGGCTTCGTCATGGTCATAGGTTCTTTATTAAA
AGTACCTGAATCATTAACAGTGACAAATCGTGAGTCAAGTAGTGGATTAAAGACAATGTTTAAAAACTTCAAAATATTAT
TGAAGACGCCACGTTTTGTATTACCAATGCTCATTCAAGGTATGACATTTGTAATATTATTTACTTATATTTCTGCGTCT
CCGTTTATTATTCAAAAAATTTATGGCATGACTGCAATACAATTTAGTTGGATGTTTGCAGGAATTGGTATTACGCTCAT
TATATCAAGTCAACTTACTGGGTACCTTGTTGATTTTATAGACTCACAAAAATTGATGAGAGGCATGACGATGATTCAGA
TTATCGGTGTAATTTTAGTGACGATTGTATTGCTTAATCATTGGAACTTTTGGTTTTAG

Upstream 100 bases:

>100_bases
TGAAACTTGTGACTAATGCTAATATATAAAAGAGCATATTTAAATTTAGTTTCTGTTCGTGATAGTTATAAACTAATCAT
TATATAAAGGAGATAGTCAT

Downstream 100 bases:

>100_bases
CGATAGGATTTATCATTTTAATAGCACCAGTGACAGGTGTTGCGACACTTGGTTTTACAATAGCTATGGATGAAAGTAGT
AGTGGTAGAGGGAGTTCATC

Product: hypothetical protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MNDLTHFNKRSPIFIIILGSLTAIGALSIDMFLPGLPDIRHDFQTTTSNAQLTLSMFMIGLAFGNLFAGPISDSTGRRKP
LIIAMIIFTLASLGIVFVHNIWLMVALRFLQGVTGGAAAVISRAIASDMYSGNELTKFMALLMLVNGIAPVVAPTIGGII
LNYSVWRMVFVILTIFGFVMVIGSLLKVPESLTVTNRESSSGLKTMFKNFKILLKTPRFVLPMLIQGMTFVILFTYISAS
PFIIQKIYGMTAIQFSWMFAGIGITLIISSQLTGYLVDFIDSQKLMRGMTMIQIIGVILVTIVLLNHWNFWF

Sequences:

>Translated_312_residues
MNDLTHFNKRSPIFIIILGSLTAIGALSIDMFLPGLPDIRHDFQTTTSNAQLTLSMFMIGLAFGNLFAGPISDSTGRRKP
LIIAMIIFTLASLGIVFVHNIWLMVALRFLQGVTGGAAAVISRAIASDMYSGNELTKFMALLMLVNGIAPVVAPTIGGII
LNYSVWRMVFVILTIFGFVMVIGSLLKVPESLTVTNRESSSGLKTMFKNFKILLKTPRFVLPMLIQGMTFVILFTYISAS
PFIIQKIYGMTAIQFSWMFAGIGITLIISSQLTGYLVDFIDSQKLMRGMTMIQIIGVILVTIVLLNHWNFWF
>Mature_312_residues
MNDLTHFNKRSPIFIIILGSLTAIGALSIDMFLPGLPDIRHDFQTTTSNAQLTLSMFMIGLAFGNLFAGPISDSTGRRKP
LIIAMIIFTLASLGIVFVHNIWLMVALRFLQGVTGGAAAVISRAIASDMYSGNELTKFMALLMLVNGIAPVVAPTIGGII
LNYSVWRMVFVILTIFGFVMVIGSLLKVPESLTVTNRESSSGLKTMFKNFKILLKTPRFVLPMLIQGMTFVILFTYISAS
PFIIQKIYGMTAIQFSWMFAGIGITLIISSQLTGYLVDFIDSQKLMRGMTMIQIIGVILVTIVLLNHWNFWF

Specific function: Involved In Sulfonamide (Sulfathiazole) And Bicyclomycin Resistance. Probable Membrane Translocase. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI1788509, Length=297, Percent_Identity=30.3030303030303, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI48994889, Length=234, Percent_Identity=32.4786324786325, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790794, Length=276, Percent_Identity=23.9130434782609, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790146, Length=243, Percent_Identity=27.5720164609054, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787065, Length=215, Percent_Identity=27.4418604651163, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082312, Length=237, Percent_Identity=24.8945147679325, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787880, Length=235, Percent_Identity=27.6595744680851, Blast_Score=61, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319480, Length=294, Percent_Identity=19.7278911564626, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321838, Length=267, Percent_Identity=22.4719101123595, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 34468; Mature: 34468

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLTHFNKRSPIFIIILGSLTAIGALSIDMFLPGLPDIRHDFQTTTSNAQLTLSMFMIG
CCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHH
LAFGNLFAGPISDSTGRRKPLIIAMIIFTLASLGIVFVHNIWLMVALRFLQGVTGGAAAV
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ISRAIASDMYSGNELTKFMALLMLVNGIAPVVAPTIGGIILNYSVWRMVFVILTIFGFVM
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGSLLKVPESLTVTNRESSSGLKTMFKNFKILLKTPRFVLPMLIQGMTFVILFTYISAS
HHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCC
PFIIQKIYGMTAIQFSWMFAGIGITLIISSQLTGYLVDFIDSQKLMRGMTMIQIIGVILV
HHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVLLNHWNFWF
HHHHHHCCCCCC
>Mature Secondary Structure
MNDLTHFNKRSPIFIIILGSLTAIGALSIDMFLPGLPDIRHDFQTTTSNAQLTLSMFMIG
CCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHH
LAFGNLFAGPISDSTGRRKPLIIAMIIFTLASLGIVFVHNIWLMVALRFLQGVTGGAAAV
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ISRAIASDMYSGNELTKFMALLMLVNGIAPVVAPTIGGIILNYSVWRMVFVILTIFGFVM
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGSLLKVPESLTVTNRESSSGLKTMFKNFKILLKTPRFVLPMLIQGMTFVILFTYISAS
HHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCC
PFIIQKIYGMTAIQFSWMFAGIGITLIISSQLTGYLVDFIDSQKLMRGMTMIQIIGVILV
HHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIVLLNHWNFWF
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9202461 [H]