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The map label for this gene is moeB [H]

Identifier: 88196191

GI number: 88196191

Start: 2341230

End: 2342234

Strand: Reverse

Name: moeB [H]

Synonym: SAOUHSC_02545

Alternate gene names: 88196191

Gene position: 2342234-2341230 (Counterclockwise)

Preceding gene: 88196192

Following gene: 88196190

Centisome position: 83.02

GC content: 34.73

Gene sequence:

>1005_bases
GTGAGTCAAGAACGTTATTCAAGGCAAATTTTATTTAAACAAATAGGTGAAATAGGTCAAAGCAAAATAAATCAAAAATG
TGCGTTGATTATTGGTATGGGCGCATTAGGTACACATGTGGCCGAAGGACTTGTTAGAGCAGGCATTGCCAAACTAATCA
TTGTTGATAGAGATTATATTGAATTTAGTAATTTACAAAGACAAACATTGTTTACTGAAGAAGATGCTTTGAAAATGATG
CCTAAGGTGGTTGCAGCTAAAAAGCATTTGCTAGCGTTACGTAGTGATGTTGATATTGATGATTATATTGCCCATGTGGA
TTATTATTTTTTGGAAACACATGGACAGGACGTTGACGTTATTATTGATGCAACCGATAACTTTGAAACACGACAACTGA
TTAATGATTTTGCATATAAATATCGTATACCTTGGATTTATGGTGGTGTTGTACAGAGTACATATACAGAAGCTGCATTT
ATACCTGGTAAAACACCTTGCTTTAACTGTTTGGTACCACAATTGCCAGCATTAAATTTAACATGTGATACAGTAGGGGT
CATTCAACCTGCCGTGACGATGGCAACAAGTTTACAATTAAGAGATGCGATGAAAGTATTAACGGAACAACCAATTGACA
CAAAAATAACTTATGGCGATATTTGGGAAGGTAGTCATTATTCATTTGGTTTCAGTAAAATGCAACGTTCAGACTGTACA
ACTTGTGGAGATGTACCAAGTTATCCGTATTTAAACAAGAATGAACAACGTTATGCAACATTGTGTGGTAGAGACACTGT
ACAGTATGAAAATGCATCAATTACACACGACATTCTTGTTCAATTTTTAAAACAACATCAGTTAAATTATCGCAGTAATT
CGTATATGGTTATGTTTGAATTTAAAGGACACCGCATTGTTGCTTTTAAAGGTGGAAGGTTTTTAATACATGGCATGACA
CGCACATCAGATGCCACACATCTAATGAATTTATTGTTTGGATAA

Upstream 100 bases:

>100_bases
TTAATGATGTTTTAAACTCTTTTTTAGGGGCAGTTTTTTTGAGAGACATTGACGCGCGTCATATAATGAAAGTAATGATA
AAAAGAAAGGATAACTTAAT

Downstream 100 bases:

>100_bases
AAAAAGATAAGACAAAAGGAGTGTAATATTATGGGCGAACATCAAAACGTTAAATTGAATCGTACAGTTAAAGCAGCCGT
ACTAACGGTATCAGATACTA

Product: hypothetical protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMM
PKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAF
IPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCT
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMT
RTSDATHLMNLLFG

Sequences:

>Translated_334_residues
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMM
PKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAF
IPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCT
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMT
RTSDATHLMNLLFG
>Mature_333_residues
SQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMP
KVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFI
PGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTT
CGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTR
TSDATHLMNLLFG

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=254, Percent_Identity=28.740157480315, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI13376212, Length=248, Percent_Identity=27.4193548387097, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787048, Length=243, Percent_Identity=30.0411522633745, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI87082356, Length=247, Percent_Identity=33.1983805668016, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17540406, Length=248, Percent_Identity=30.6451612903226, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17508819, Length=183, Percent_Identity=31.6939890710383, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=271, Percent_Identity=25.0922509225092, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320598, Length=177, Percent_Identity=28.8135593220339, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325323, Length=160, Percent_Identity=31.875, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24582879, Length=254, Percent_Identity=29.1338582677165, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24641311, Length=190, Percent_Identity=33.1578947368421, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 37921; Mature: 37790

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYI
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCEEEEEEECCHH
EFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDV
HHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCCEEE
IIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNL
EEECCCCHHHHHHHHHHHHEEECCEEECCHHHHHCCCEEECCCCCCHHHHHCCCCCCCEE
TCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCT
EECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCC
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFE
CCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEE
FKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
ECCCEEEEEECCEEEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYI
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCEEEEEEECCHH
EFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDV
HHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCCEEE
IIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNL
EEECCCCHHHHHHHHHHHHEEECCEEECCHHHHHCCCEEECCCCCCHHHHHCCCCCCCEE
TCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCT
EECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCC
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFE
CCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEE
FKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
ECCCEEEEEECCEEEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]