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The map label for this gene is moeA

Identifier: 88196188

GI number: 88196188

Start: 2338875

End: 2340134

Strand: Reverse

Name: moeA

Synonym: SAOUHSC_02542

Alternate gene names: 88196188

Gene position: 2340134-2338875 (Counterclockwise)

Preceding gene: 88196190

Following gene: 88196187

Centisome position: 82.94

GC content: 37.7

Gene sequence:

>1260_bases
ATGGTAGTAGAAAAAAGAAACCCAATCCCAGTTAAAGAAGCAATTCAACGTATCGTTAATCAGCAGAGTTCAATGCCGGC
AATTACGGTAGCACTTGAAAAAAGTCTAAATCATATCTTAGCAGAAGATATTGTAGCTACTTATGATATACCAAGGTTTG
ATAAATCACCTTATGATGGTTTTGCAATTCGCAGTGTTGATTCACAAGGGGCAAGTGGTCAGAATCGCATTGAGTTTAAA
GTGATTGATCATATTGGTGCAGGTTCAGTTTCTGATAAATTAGTTGGGGATCACGAAGCGGTGCGTATTATGACTGGAGC
ACAAATACCTAATGGCGCAGATGCTGTTGTTATGTTTGAACAAACGATTGAACTAGAAGATACATTTACAATTCGTAAAC
CATTTTCAAAAAATGAAAATATATCTTTAAAAGGTGAAGAAACAAAGACAGGCGATGTTGTTCTAAAAAAAGGACAAGTA
ATTAATCCAGGGGCTATCGCGGTCCTTGCAACATATGGCTATGCAGAGGTTAAAGTTATTAAGCAACCGAGTGTCGCTGT
TATTGCAACAGGAAGCGAATTATTAGATGTTAATGATGTATTAGAAGATGGGAAAATTCGTAACTCTAATGGCCCAATGA
TTCGTGCCTTAGCAGAAAAATTAGGTCTTGAAGTTGGTATTTACAAAACACAAAAAGATGATTTAGATAGTGGCATCCAA
GTCGTTAAAGAAGCTATGGAAAAACATGATATCGTTATTACAACGGGCGGAGTTTCTGTTGGAGATTTTGACTATTTACC
TGAGATTTATAAGGCTGTAAAGGCGGAAGTGTTATTTAATAAAGTAGCAATGCGTCCTGGTAGCGTAACAACGGTTGCAT
TTGTAGATGGAAAGTATTTGTTTGGATTATCTGGAAATCCATCAGCTTGTTTTACAGGATTTGAACTATTTGTGAAACCA
GCTGTTAAACATATGTGTGGCGCACTAGAAGTCTTCCCGCAAATAATTAAAGCAACATTAATGGAAGATTTTACCAAGGC
AAACCCATTCACACGATTTATACGTGCTAAAGCAACGTTAACAAGTGCTGGAGCTACTGTAGTACCTTCAGGATTCAATA
AATCAGGTGCGGTTGTAGCGATTGCACATGCTAACTGTATGGTCATGTTACCAGGAGGGTCACGTGGTTTTAAAGCGGGG
CATACAGTAGATATTATATTGACTGAATCTGACGCTGCTGAAGAGGAACTTCTTTTATGA

Upstream 100 bases:

>100_bases
GCGTGGCCTTGTTGATTAATATGAGTAAACTCAGTCATTTTACCCCTCCTAGTGCATCTAGTATATCATGAAAAAATAAA
AGTTTTGGAGATGATTTTTA

Downstream 100 bases:

>100_bases
TTTTACAAATTGTAGGTTACAAAAAGTCTGGTAAGACAACATTGATGAGGCATATTGTCTCTTTCTTAAAGTCACATGGT
TATACAGTTGCTACTATTAA

Product: molybdopterin biosynthesis protein moeA

Products: NA

Alternate protein names: MPT Mo-transferase

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFK
VIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQV
INPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQ
VVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKP
AVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAG
HTVDIILTESDAAEEELLL

Sequences:

>Translated_419_residues
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFK
VIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQV
INPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQ
VVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKP
AVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAG
HTVDIILTESDAAEEELLL
>Mature_419_residues
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFK
VIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQV
INPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQ
VVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKP
AVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAG
HTVDIILTESDAAEEELLL

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family

Homologues:

Organism=Homo sapiens, GI66932975, Length=401, Percent_Identity=33.9152119700748, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI10880983, Length=401, Percent_Identity=33.9152119700748, Blast_Score=183, Evalue=3e-46,
Organism=Escherichia coli, GI1787049, Length=299, Percent_Identity=34.1137123745819, Blast_Score=156, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25147659, Length=342, Percent_Identity=30.9941520467836, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17562606, Length=378, Percent_Identity=26.7195767195767, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI17136978, Length=398, Percent_Identity=29.3969849246231, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24638841, Length=398, Percent_Identity=29.3969849246231, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOEA_STAAC (Q5HDT4)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_187073.1
- ProteinModelPortal:   Q5HDT4
- STRING:   Q5HDT4
- EnsemblBacteria:   EBSTAT00000009223
- GeneID:   3237397
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL2266
- TIGR:   SACOL2266
- eggNOG:   COG0303
- GeneTree:   EBGT00050000025313
- HOGENOM:   HBG731522
- OMA:   IPSGCDA
- ProtClustDB:   CLSK2518167
- BioCyc:   SAUR93062:SACOL2266-MONOMER
- InterPro:   IPR020817
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- SMART:   SM00852
- TIGRFAMs:   TIGR00177

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N; SSF53218 MoCF_biosynth; SSF63867 MoeA_C; SSF63882 MoeA_N

EC number: NA

Molecular weight: Translated: 45017; Mature: 45017

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDG
CCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFE
EEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEE
QTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVI
EEECCCCEEEEECCCCCCCCEEEECCCCCCCCEEEECCCEECCCCEEEEEECCCEEEEEE
KQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQ
ECCCEEEEECCCHHCCHHHHHCCCEEECCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHH
VVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYL
HHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEE
FGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATL
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEE
TSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
ECCCCEEECCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCEEEEEEECCCCCCHHCCC
>Mature Secondary Structure
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDG
CCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFE
EEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEE
QTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVI
EEECCCCEEEEECCCCCCCCEEEECCCCCCCCEEEECCCEECCCCEEEEEECCCEEEEEE
KQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQ
ECCCEEEEECCCHHCCHHHHHCCCEEECCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHH
VVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYL
HHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEE
FGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATL
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEE
TSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
ECCCCEEECCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCEEEEEEECCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA