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The map label for this gene is pbuG [H]

Identifier: 88196164

GI number: 88196164

Start: 2319077

End: 2320255

Strand: Reverse

Name: pbuG [H]

Synonym: SAOUHSC_02516

Alternate gene names: 88196164

Gene position: 2320255-2319077 (Counterclockwise)

Preceding gene: 88196165

Following gene: 88196162

Centisome position: 82.24

GC content: 36.05

Gene sequence:

>1179_bases
ATGGACCAAGGTGCCATTTTTGTAGCGACTGCATTAGCAGCATTTGTAGGCTCGCTATTCATGGGGCTAATAGCTAAATA
TCCAATTGCGTTAGCACCAGGTATGGGATTAAATGCATTCTTTGCATTTACTGTTGTGTTAACCATGGGTATTCCTTGGC
AAGTTGGTTTAACAGGCGTTTTATTCTCAGGTATATTCTTTGCGATATTAACCGTCACAGGGTTTAGGGAAGTTATTATT
AATGCAATTCCTTATCAAATGAAGATGGCTGTTTCAGCAGGTATAGGATTATTCATTACATTTGTAGGTTTACAAAGTTC
GGGTATTATAGTTAAAAATGAATCTACATTAGTAACATTGGGACATTTAACTGATCCACCAGTACTTTTGGCGATATTCG
GTATCGTTATTACAGTTATTTTATATGCAATTAAATTGCCGGGTTCTATCTTTATCGGTATGATCATCACAGCAATCGTT
GGTATGTTCACTGGATTGATTCAAATGCCATCTGGTATTGTGGGTAAGATTCCAAGTATTGAACCAACGTTCGGTGCTGC
ATTTGAAGCGTTTAAAGACCCAAGTCAATTATTAACGATACAGTTCTTAATTGTTATTTTAACGTTCTTATTTATTGATT
TCTTTGATACAGCTGGTACATTAGTAGCTGTTGCTACTCAAGCAGGTATTATGAAAGATAATAAATTACCAAGAGCTGGT
AGAGCATTGTTCTCAGATTCTTTAGCTACGATTGTAGGATCAGTTTTTGGAACAACTACAACAACTTCTTATATCGAATC
AACTTCAGGTGTTGCTGTAGGTGCTAGAACAGGATTTGCTAGTATCGTAACAGGTTGTTGTTTCCTATTAGCGCTGTTCT
TTAGTCCGTTAATCGCTGTTGTAACAAGTGCAGTTACGACACCAGCCTTAGTGGTGGTAGGTGTATTAATGGCTGCAAAC
TTTGCTGAGATAAACTGGAAAAGTTTTGAAGTTGCAGTGCCAGCCTTCATTACAATCATTATGATGCCTTTATCATATTC
AATTGCAACTGGTATTGCGTGTGGATTTATTTTCTATCCAATTACAATGCTTATCTCTAAAAAACATAAAGAAGTACATC
CGATAATGTATGTATTAATGGTACTATTCATTCTGTACTTCATATTTGTTCATGGTTAA

Upstream 100 bases:

>100_bases
AGGCGGTATCACAACTTTCTTATCTATGGCCTATATTTTAGCAGTTAACCCGCAAGTTTTAAGTTTAGCAGGTGTTAAAG
GCGTATCAGAAGATATGAAA

Downstream 100 bases:

>100_bases
ATCCAGACACAAAAAACGACTGCCAATGATTGGTAGTCGTTTTTTTCTTTGAAGTAAGGATAAAATAAGAAGCGAAATAA
CATAAAGCGATATTATGAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MDQGAIFVATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVII
NAIPYQMKMAVSAGIGLFITFVGLQSSGIIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIV
GMFTGLIQMPSGIVGKIPSIEPTFGAAFEAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAG
RALFSDSLATIVGSVFGTTTTTSYIESTSGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAAN
FAEINWKSFEVAVPAFITIIMMPLSYSIATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG

Sequences:

>Translated_392_residues
MDQGAIFVATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVII
NAIPYQMKMAVSAGIGLFITFVGLQSSGIIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIV
GMFTGLIQMPSGIVGKIPSIEPTFGAAFEAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAG
RALFSDSLATIVGSVFGTTTTTSYIESTSGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAAN
FAEINWKSFEVAVPAFITIIMMPLSYSIATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG
>Mature_392_residues
MDQGAIFVATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMGIPWQVGLTGVLFSGIFFAILTVTGFREVII
NAIPYQMKMAVSAGIGLFITFVGLQSSGIIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIV
GMFTGLIQMPSGIVGKIPSIEPTFGAAFEAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAG
RALFSDSLATIVGSVFGTTTTTSYIESTSGVAVGARTGFASIVTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAAN
FAEINWKSFEVAVPAFITIIMMPLSYSIATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=392, Percent_Identity=41.0714285714286, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1790150, Length=392, Percent_Identity=40.8163265306122, Blast_Score=284, Evalue=9e-78,
Organism=Escherichia coli, GI1790499, Length=393, Percent_Identity=32.824427480916, Blast_Score=187, Evalue=8e-49,
Organism=Escherichia coli, GI48994909, Length=381, Percent_Identity=33.3333333333333, Blast_Score=173, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 41579; Mature: 41579

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQGAIFVATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMGIPWQVGLTGV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
LFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSGIIVKNESTLVTL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCEEEE
GHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSI
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EPTFGAAFEAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAG
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHH
RALFSDSLATIVGSVFGTTTTTSYIESTSGVAVGARTGFASIVTGCCFLLALFFSPLIAV
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHH
VTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSIATGIACGFIFYP
HHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITMLISKKHKEVHPIMYVLMVLFILYFIFVHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDQGAIFVATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMGIPWQVGLTGV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
LFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSGIIVKNESTLVTL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCEEEE
GHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGLIQMPSGIVGKIPSI
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EPTFGAAFEAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAVATQAGIMKDNKLPRAG
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHH
RALFSDSLATIVGSVFGTTTTTSYIESTSGVAVGARTGFASIVTGCCFLLALFFSPLIAV
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHH
VTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITIIMMPLSYSIATGIACGFIFYP
HHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITMLISKKHKEVHPIMYVLMVLFILYFIFVHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]