Click here to switch to the map view.

The map label for this gene is ribD [H]

Identifier: 88195585

GI number: 88195585

Start: 1800919

End: 1801923

Strand: Reverse

Name: ribD [H]

Synonym: SAOUHSC_01889

Alternate gene names: 88195585

Gene position: 1801923-1800919 (Counterclockwise)

Preceding gene: 88195586

Following gene: 88195584

Centisome position: 63.87

GC content: 35.02

Gene sequence:

>1005_bases
ATGGTACAAGGTCAAACAGGTGTTAATCCACCCGTTGGCGCTGTTGTAGTTAAAGAAGGTAGGATTGTTGGTATTGGTGC
ACACTTGAGAAAAGGTGACAAGCATGCGGAGGTTCAAGCACTTGATATGGCACAACAAAATGCTGAAGGTGCGACGATTT
ATATTACGTTAGAGCCATGTAGTCATTTTGGTTCAACACCACCCTGTGTTAACAAAATAATTGATTGTAAGATAGCAAAA
GTAGTATACGCAACAAAAGACAATTCGTTAGACACACATGGTGATGAGACGTTACGGGCTCACGGTATTGAGGTTGAATG
CGTTGATGATGAACGGGCATCACAATTATACCAAGACTTTTTTAAAGCAAAAGCAAAGCAACTGCCACAAATTACAGTGA
AAGTATCTGCAAGTTTAGATGGTAAACAAGCGAATGATAATGGACAAAGTCAATGGATTACTAACAAAGAGGTTAAACAA
GATGTCTATAAGTTAAGACATCGACACGACGCAGTGTTAACTGGAAGACGTACAGTTGAATTAGATGATCCACAATATAC
TACACGTATTCAAGATGGAAAAAACCCTATAAAAGTAATATTGTCTAAGTCTGGGAATATTCATTTTAATCAGCAAATTT
ATCAAGATGAATCAACACCAATTTGGATATATACTGAAAATCCAAATTTAACAACCAATCAAACACATATTGAAATTATT
TACTTGAAGTCTTGCGATTTAACAACAATTCTTCACAATTTATATAAAAGAGGAGTTGGAACTTTGCTAGTCGAGGCAGG
TCCAACCACTACTTCAGAATTTCTCCAATCTAATTATATAGATGAATTTATTCTCTATTATGCCCCGAAATTAATTGGCG
GATCTGGAAATTATCAATTTTATCAAACAAATGATGTGATTGAGATACCAGATGCGAACCAATTTGAAATTGTTCATTCC
GAGTTATTAAATCAAAATGTTAAATTAACTTTACGAAAGAAGTGA

Upstream 100 bases:

>100_bases
AAATTTTTCTCCTTGCATCTTAATTCATGATGTGAGGATTTTTGTTTATAGAGGTGATCATTTGAGTCAATTTATGGATT
ATGCGATTCAACTTGCAAAT

Downstream 100 bases:

>100_bases
TGATGCATGTTTACTGGCATCGTTGAAGAAATAGGTGTCGTTAAAAGTGTTCAAATTCGTCAATCAGTCAGGACGATTGA
AATTGAAGCACATAAGATTA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MVQGQTGVNPPVGAVVVKEGRIVGIGAHLRKGDKHAEVQALDMAQQNAEGATIYITLEPCSHFGSTPPCVNKIIDCKIAK
VVYATKDNSLDTHGDETLRAHGIEVECVDDERASQLYQDFFKAKAKQLPQITVKVSASLDGKQANDNGQSQWITNKEVKQ
DVYKLRHRHDAVLTGRRTVELDDPQYTTRIQDGKNPIKVILSKSGNIHFNQQIYQDESTPIWIYTENPNLTTNQTHIEII
YLKSCDLTTILHNLYKRGVGTLLVEAGPTTTSEFLQSNYIDEFILYYAPKLIGGSGNYQFYQTNDVIEIPDANQFEIVHS
ELLNQNVKLTLRKK

Sequences:

>Translated_334_residues
MVQGQTGVNPPVGAVVVKEGRIVGIGAHLRKGDKHAEVQALDMAQQNAEGATIYITLEPCSHFGSTPPCVNKIIDCKIAK
VVYATKDNSLDTHGDETLRAHGIEVECVDDERASQLYQDFFKAKAKQLPQITVKVSASLDGKQANDNGQSQWITNKEVKQ
DVYKLRHRHDAVLTGRRTVELDDPQYTTRIQDGKNPIKVILSKSGNIHFNQQIYQDESTPIWIYTENPNLTTNQTHIEII
YLKSCDLTTILHNLYKRGVGTLLVEAGPTTTSEFLQSNYIDEFILYYAPKLIGGSGNYQFYQTNDVIEIPDANQFEIVHS
ELLNQNVKLTLRKK
>Mature_334_residues
MVQGQTGVNPPVGAVVVKEGRIVGIGAHLRKGDKHAEVQALDMAQQNAEGATIYITLEPCSHFGSTPPCVNKIIDCKIAK
VVYATKDNSLDTHGDETLRAHGIEVECVDDERASQLYQDFFKAKAKQLPQITVKVSASLDGKQANDNGQSQWITNKEVKQ
DVYKLRHRHDAVLTGRRTVELDDPQYTTRIQDGKNPIKVILSKSGNIHFNQQIYQDESTPIWIYTENPNLTTNQTHIEII
YLKSCDLTTILHNLYKRGVGTLLVEAGPTTTSEFLQSNYIDEFILYYAPKLIGGSGNYQFYQTNDVIEIPDANQFEIVHS
ELLNQNVKLTLRKK

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=342, Percent_Identity=35.0877192982456, Blast_Score=194, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 37440; Mature: 37440

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQGQTGVNPPVGAVVVKEGRIVGIGAHLRKGDKHAEVQALDMAQQNAEGATIYITLEPC
CCCCCCCCCCCCCEEEEECCEEEEEEHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCH
SHFGSTPPCVNKIIDCKIAKVVYATKDNSLDTHGDETLRAHGIEVECVDDERASQLYQDF
HHCCCCCHHHHHHHCCEEEEEEEEECCCCCCCCCCCHHEECCCEEEEECCHHHHHHHHHH
FKAKAKQLPQITVKVSASLDGKQANDNGQSQWITNKEVKQDVYKLRHRHDAVLTGRRTVE
HHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCEEEE
LDDPQYTTRIQDGKNPIKVILSKSGNIHFNQQIYQDESTPIWIYTENPNLTTNQTHIEII
ECCCCEEEEECCCCCCEEEEEECCCCEEECHHEECCCCCEEEEEECCCCCCCCCEEEEEE
YLKSCDLTTILHNLYKRGVGTLLVEAGPTTTSEFLQSNYIDEFILYYAPKLIGGSGNYQF
EEECCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
YQTNDVIEIPDANQFEIVHSELLNQNVKLTLRKK
EECCCEEECCCCCCHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MVQGQTGVNPPVGAVVVKEGRIVGIGAHLRKGDKHAEVQALDMAQQNAEGATIYITLEPC
CCCCCCCCCCCCCEEEEECCEEEEEEHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCH
SHFGSTPPCVNKIIDCKIAKVVYATKDNSLDTHGDETLRAHGIEVECVDDERASQLYQDF
HHCCCCCHHHHHHHCCEEEEEEEEECCCCCCCCCCCHHEECCCEEEEECCHHHHHHHHHH
FKAKAKQLPQITVKVSASLDGKQANDNGQSQWITNKEVKQDVYKLRHRHDAVLTGRRTVE
HHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCEEEE
LDDPQYTTRIQDGKNPIKVILSKSGNIHFNQQIYQDESTPIWIYTENPNLTTNQTHIEII
ECCCCEEEEECCCCCCEEEEEECCCCEEECHHEECCCCCEEEEEECCCCCCCCCEEEEEE
YLKSCDLTTILHNLYKRGVGTLLVEAGPTTTSEFLQSNYIDEFILYYAPKLIGGSGNYQF
EEECCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
YQTNDVIEIPDANQFEIVHSELLNQNVKLTLRKK
EECCCEEECCCCCCHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]