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The map label for this gene is cymR [H]

Identifier: 88195436

GI number: 88195436

Start: 1636204

End: 1636554

Strand: Reverse

Name: cymR [H]

Synonym: SAOUHSC_01732

Alternate gene names: 88195436

Gene position: 1636554-1636204 (Counterclockwise)

Preceding gene: 88195437

Following gene: 88195435

Centisome position: 58.01

GC content: 36.47

Gene sequence:

>351_bases
ATGAAAATTTCTACTAAAGGGAGATATGGACTTACATTGATGATTTCTCTTGCTAAAAAAGAGGGGCAAGGATGTATATC
ATTAAAGTCAATTGCTGAAGAAAATAATTTGAGTGATTTATATTTAGAACAGCTTGTAGGTCCTTTAAGAAATGCGGGGT
TAATTCGAAGTGTACGCGGTGCTAAAGGTGGATACCAATTAAGAGTGCCAGCGGAAGAAATCTCAGCAGGGGATATTATA
AGACTGTTAGAAGGTCCAATTACATTTGTTGAAAGTATTGAATCAGAACCACCTGCGCAAAAAACAACTATGGATTCGCA
TGAGAGATGCAGTGAGAGATGTTTTAGATAA

Upstream 100 bases:

>100_bases
ATGGTTCTGTACTCACATTTGTCACACCTTTCTTATACTATCTTAACTCAAAAAATGCTAAAATGGGAATATCAATATTC
GAATTAAGTGAGGTTATACA

Downstream 100 bases:

>100_bases
TACAACATTGAAATATTTAGCGGAATATGTAGATACAAGTGAAGATTTAGACGGATACATGTTTTATATTTAATCGTATA
AATACTATACTATAACATAA

Product: hypothetical protein

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDII
RLLEGPITFVESIESEPPAQKTTMDSHERCSERCFR

Sequences:

>Translated_116_residues
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDII
RLLEGPITFVESIESEPPAQKTTMDSHERCSERCFR
>Mature_116_residues
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDII
RLLEGPITFVESIESEPPAQKTTMDSHERCSERCFR

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=84, Percent_Identity=40.4761904761905, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 12768; Mature: 12768

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRG
CCCCCCCCCCEEEEEEEHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCC
AKGGYQLRVPAEEISAGDIIRLLEGPITFVESIESEPPAQKTTMDSHERCSERCFR
CCCCEEEECCHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRG
CCCCCCCCCCEEEEEEEHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCC
AKGGYQLRVPAEEISAGDIIRLLEGPITFVESIESEPPAQKTTMDSHERCSERCFR
CCCCEEEECCHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]