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The map label for this gene is gluP [H]

Identifier: 88195357

GI number: 88195357

Start: 1562911

End: 1563921

Strand: Reverse

Name: gluP [H]

Synonym: SAOUHSC_01649

Alternate gene names: 88195357

Gene position: 1563921-1562911 (Counterclockwise)

Preceding gene: 88195358

Following gene: 88195356

Centisome position: 55.43

GC content: 28.09

Gene sequence:

>1011_bases
ATGAACATAGACAAACAATTTTGGAAAACAATATATTATTGGATTAGGTACTTGAATTTTGATATTGTCAGTAGGGAAAA
AGATGACCAAGAAATTTGGTTAGCCCATAAAAGAAAAAAACAAGTAGTCATTTTTAAACAACATATCAAGTCTACCCAAG
AAATACGTTTTGACAAAGCGAAAGTGCTTGAACACAAAGATGAAATAGCAAATTTTATTTCTTTCGAACCACAAAGTTTT
GAATTTTATTATTTTACAGAATCGGAATTTTCAGAAGAACAATTAAATGAAGTTTCGCCAATTAGAATTAAATTCAATGT
TATAAGACACACAAAAGATTTGATAAAGCATATGCCGAATATATTTTTGGCTAGACTTATTTCAGAAGATAATGATAAAA
AGACATATATGTTCTATAAACGCAAAGTATTAACCGATAACTTTTTAGATAAATATATGCAGAAATTTTCACCGGCAACA
TACACAATAATATTTGTAAATGTCTTAATATGGTTATGTATGATTTTATATTTAAATAATTTTTCGGATGTAAAATTATT
AGATGTTGGCGGGTTAGTGCATTTTAATGTCGTACATGGTGAATGGTATCGAATTGTTACATCGATGTTTTTACATTTTA
GTTTTGAACATATACTTATGAATATGCTTTCATTATTTATTTTTGGTAAAATAGTCGAAGCAATTATTGGTTCATGGCGG
ATGTTAACTGTATACTTTATTGCAGGGTTGTTTGGAAACTTTGTATCACTATCATTTAATACGACTACAATTTCAGTTGG
GGCTAGTGGTGCTATATTTGGTCTGATTGGATCAATTTTTGCGATGATGTATGTTTCAAAAACATTTAACAAAAAAATGT
TAGGACAGTTATTAATTGCATTAGTGATATTAGTTGGTGTTTCTCTGTTTATGTCAAATATAAATATTGTGGCGCATATT
GGAGGATTCATTGGTGGTTTATTAATAACTTTAATTGGCTATTACTATTAA

Upstream 100 bases:

>100_bases
GCTTATTATACGATTTTCAAATAACATCATTTGAACCGGAATCATTCGATCAACCAGTCGATAAATTGATTATATATCAA
GCAGCATAGTGGAGGACTAA

Downstream 100 bases:

>100_bases
GTGAATCGTAATATTTTTTGGATTTTACTAATTGGTATGCTTGTTATATTTATTGCACTTCAAATTAGAATTTTTACAAT
TAAAGAAGATAATATTTATA

Product: rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNIDKQFWKTIYYWIRYLNFDIVSREKDDQEIWLAHKRKKQVVIFKQHIKSTQEIRFDKAKVLEHKDEIANFISFEPQSF
EFYYFTESEFSEEQLNEVSPIRIKFNVIRHTKDLIKHMPNIFLARLISEDNDKKTYMFYKRKVLTDNFLDKYMQKFSPAT
YTIIFVNVLIWLCMILYLNNFSDVKLLDVGGLVHFNVVHGEWYRIVTSMFLHFSFEHILMNMLSLFIFGKIVEAIIGSWR
MLTVYFIAGLFGNFVSLSFNTTTISVGASGAIFGLIGSIFAMMYVSKTFNKKMLGQLLIALVILVGVSLFMSNINIVAHI
GGFIGGLLITLIGYYY

Sequences:

>Translated_336_residues
MNIDKQFWKTIYYWIRYLNFDIVSREKDDQEIWLAHKRKKQVVIFKQHIKSTQEIRFDKAKVLEHKDEIANFISFEPQSF
EFYYFTESEFSEEQLNEVSPIRIKFNVIRHTKDLIKHMPNIFLARLISEDNDKKTYMFYKRKVLTDNFLDKYMQKFSPAT
YTIIFVNVLIWLCMILYLNNFSDVKLLDVGGLVHFNVVHGEWYRIVTSMFLHFSFEHILMNMLSLFIFGKIVEAIIGSWR
MLTVYFIAGLFGNFVSLSFNTTTISVGASGAIFGLIGSIFAMMYVSKTFNKKMLGQLLIALVILVGVSLFMSNINIVAHI
GGFIGGLLITLIGYYY
>Mature_336_residues
MNIDKQFWKTIYYWIRYLNFDIVSREKDDQEIWLAHKRKKQVVIFKQHIKSTQEIRFDKAKVLEHKDEIANFISFEPQSF
EFYYFTESEFSEEQLNEVSPIRIKFNVIRHTKDLIKHMPNIFLARLISEDNDKKTYMFYKRKVLTDNFLDKYMQKFSPAT
YTIIFVNVLIWLCMILYLNNFSDVKLLDVGGLVHFNVVHGEWYRIVTSMFLHFSFEHILMNMLSLFIFGKIVEAIIGSWR
MLTVYFIAGLFGNFVSLSFNTTTISVGASGAIFGLIGSIFAMMYVSKTFNKKMLGQLLIALVILVGVSLFMSNINIVAHI
GGFIGGLLITLIGYYY

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 39399; Mature: 39399

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDKQFWKTIYYWIRYLNFDIVSREKDDQEIWLAHKRKKQVVIFKQHIKSTQEIRFDKA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHH
KVLEHKDEIANFISFEPQSFEFYYFTESEFSEEQLNEVSPIRIKFNVIRHTKDLIKHMPN
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHH
IFLARLISEDNDKKTYMFYKRKVLTDNFLDKYMQKFSPATYTIIFVNVLIWLCMILYLNN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
FSDVKLLDVGGLVHFNVVHGEWYRIVTSMFLHFSFEHILMNMLSLFIFGKIVEAIIGSWR
CCCEEEEEECCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
MLTVYFIAGLFGNFVSLSFNTTTISVGASGAIFGLIGSIFAMMYVSKTFNKKMLGQLLIA
HHHHHHHHHHHHHHEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVILVGVSLFMSNINIVAHIGGFIGGLLITLIGYYY
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIDKQFWKTIYYWIRYLNFDIVSREKDDQEIWLAHKRKKQVVIFKQHIKSTQEIRFDKA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHH
KVLEHKDEIANFISFEPQSFEFYYFTESEFSEEQLNEVSPIRIKFNVIRHTKDLIKHMPN
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHH
IFLARLISEDNDKKTYMFYKRKVLTDNFLDKYMQKFSPATYTIIFVNVLIWLCMILYLNN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
FSDVKLLDVGGLVHFNVVHGEWYRIVTSMFLHFSFEHILMNMLSLFIFGKIVEAIIGSWR
CCCEEEEEECCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
MLTVYFIAGLFGNFVSLSFNTTTISVGASGAIFGLIGSIFAMMYVSKTFNKKMLGQLLIA
HHHHHHHHHHHHHHEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVILVGVSLFMSNINIVAHIGGFIGGLLITLIGYYY
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]