Click here to switch to the map view.

The map label for this gene is ykgC [H]

Identifier: 88194355

GI number: 88194355

Start: 583052

End: 584374

Strand: Reverse

Name: ykgC [H]

Synonym: SAOUHSC_00581

Alternate gene names: 88194355

Gene position: 584374-583052 (Counterclockwise)

Preceding gene: 88194356

Following gene: 88194348

Centisome position: 20.71

GC content: 35.22

Gene sequence:

>1323_bases
ATGAAAACATATGATTTAATTGTAATAGGATTTGGGAAAGCTGGTAAAACTTTAGCGAAATACGCTGCATCAACAGGTCA
ACACGTCGCAGTTATCGAACAATCTCCGAAAATGTATGGAGGCACTTGTATAAACATAGGATGTATACCTTCGAAGACAC
TTGTACATGATGGATTAGAAGGCAAATCTTTTGAAGCAAGTTATAACCGTAAAAACGATGTTGTCAATGCGCTAAACAAT
AAAAATTACCACTTATTAGCAGACGATAACAACATTGATGTACTGGATTTTAAAGCGCAGTTTAAATCTAATACTGAAGT
GAATTTATTAGATCAACATGACGATATCGTCGATAGTATTACTGCACCTCATATCATTATTAATACCGGTGCTACCTCTG
TCATTCCTAACATTAAAGGCCTTGATCAAGCTAAACACGTCTTCGATTCGACAGGTTTATTAAACATTAGCTATCAACCT
AAGCACCTCGTTATTGTAGGTGGCGGTTATATCGCCTTAGAATTTGCTTCAATGTTTGCGAATTTAGGTAGTAAGGTAAC
AGTATTAGAACGTGGCGAATCATTTATGCCACGCGAAGATCAAGATGTCGTTGCATATGGTATTACTGACTTAGAAAATA
AAGGCATTGCATTGCATACAAATGTTGAAACGACTGAATTGTCATCTGACAATCATCATACAACAGTCCATACCAACGTT
GGTAACTTTGAGGCTGATGCAGTACTTTTGGCTATCGGGCGCAAACCGAATACGGATTTAGCTTTAGAAAATACTGATAT
CGAATTAGGCGACAGAGGCGAAATTAAAGTCAATGCTCATCTTCAAACAACTGTGCCGCATATTTATGCTGCAGGTGATG
TTAAAGGCGGACTTCAATTTACGTATATATCTTTAGATGATTATCGAATTATCAAATCAGCGTTATATGGTAATCAGTCA
CGTACGACTGACAATAGAGGCAGCGTGCCTTATACAGTATTTATAGATCCACCATTATCACGTGTTGGATTAACTAGTAA
AGAAGCTGCCGCTCAACATTATGATTACACTGAACATCAACTTTTAGTAAGTGCTATACCTCGTCATAAAATTAACAATG
ATCCAAGAGGTTTATTTAAAGTAGTCATTAATAATGAAAATAATATGATTTTAGGTGCTACATTATATGGTAAGCAATCT
GAAGAATTAATTAATATAATTAAACTTGCGATTGATCAAAACATTCCATATACCGTATTACGAGATAATATTTATACGCA
TCCTACGATGGCCGAATCATTTAATGATTTATTTAATTTCTAG

Upstream 100 bases:

>100_bases
TCACATTATCAGCAAGACGAACAGAATATCATTATTAATTTTTATAATGGAAAAACAATCAAAGATGTCATTGAAGACAT
TCAAAAGGAGGATTTATGTC

Downstream 100 bases:

>100_bases
ACAAAACATAAAAACCTGGTGGCACGCATTGAATGATGCTGCCATCAGGCTTTATTGTTGTGCTTTTCGCTTTTCTAATT
TTTCTTTAAGCTTTCTATCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSPKMYGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNN
KNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHDDIVDSITAPHIIINTGATSVIPNIKGLDQAKHVFDSTGLLNISYQP
KHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPREDQDVVAYGITDLENKGIALHTNVETTELSSDNHHTTVHTNV
GNFEADAVLLAIGRKPNTDLALENTDIELGDRGEIKVNAHLQTTVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQS
RTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQS
EELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNF

Sequences:

>Translated_440_residues
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSPKMYGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNN
KNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHDDIVDSITAPHIIINTGATSVIPNIKGLDQAKHVFDSTGLLNISYQP
KHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPREDQDVVAYGITDLENKGIALHTNVETTELSSDNHHTTVHTNV
GNFEADAVLLAIGRKPNTDLALENTDIELGDRGEIKVNAHLQTTVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQS
RTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQS
EELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNF
>Mature_440_residues
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSPKMYGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNN
KNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHDDIVDSITAPHIIINTGATSVIPNIKGLDQAKHVFDSTGLLNISYQP
KHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPREDQDVVAYGITDLENKGIALHTNVETTELSSDNHHTTVHTNV
GNFEADAVLLAIGRKPNTDLALENTDIELGDRGEIKVNAHLQTTVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQS
RTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQS
EELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNF

Specific function: Unknown

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI91199540, Length=462, Percent_Identity=27.4891774891775, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI50301238, Length=464, Percent_Identity=27.801724137931, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI22035672, Length=483, Percent_Identity=27.536231884058, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI33519430, Length=438, Percent_Identity=25.5707762557078, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI33519428, Length=438, Percent_Identity=25.5707762557078, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI33519426, Length=438, Percent_Identity=25.5707762557078, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI148277065, Length=438, Percent_Identity=25.5707762557078, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI148277071, Length=439, Percent_Identity=25.7403189066059, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI291045266, Length=463, Percent_Identity=25.0539956803456, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI291045268, Length=459, Percent_Identity=23.3115468409586, Blast_Score=90, Evalue=5e-18,
Organism=Escherichia coli, GI87081717, Length=441, Percent_Identity=49.4331065759637, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI87082354, Length=459, Percent_Identity=29.1938997821351, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1786307, Length=451, Percent_Identity=27.4944567627494, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789915, Length=441, Percent_Identity=27.2108843537415, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1787114, Length=190, Percent_Identity=27.8947368421053, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI32565766, Length=460, Percent_Identity=28.695652173913, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17557007, Length=475, Percent_Identity=28.4210526315789, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71983429, Length=463, Percent_Identity=26.3498920086393, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71983419, Length=463, Percent_Identity=26.3498920086393, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71982272, Length=492, Percent_Identity=24.7967479674797, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6325166, Length=468, Percent_Identity=27.1367521367521, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6321091, Length=471, Percent_Identity=27.6008492569002, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6325240, Length=476, Percent_Identity=26.4705882352941, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21358499, Length=464, Percent_Identity=30.1724137931034, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24640549, Length=479, Percent_Identity=27.9749478079332, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24640553, Length=479, Percent_Identity=27.9749478079332, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24640551, Length=477, Percent_Identity=27.4633123689727, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17737741, Length=481, Percent_Identity=26.1954261954262, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: NA

Molecular weight: Translated: 48416; Mature: 48416

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00076 PYRIDINE_REDOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSPKMYGGTCINIGCIPSKTLVHDGLE
CCEEEEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHCCCC
GKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHDDIVDSI
CCCEECCCCCCHHHHHHHCCCCEEEEECCCCEEEEEEEEECCCCCEEEEECCCCHHHHHC
TAPHIIINTGATSVIPNIKGLDQAKHVFDSTGLLNISYQPKHLVIVGGGYIALEFASMFA
CCCEEEEECCCHHCCCCCCCCHHHHHHHCCCCEEEEEECCCEEEEECCCEEEHHHHHHHH
NLGSKVTVLERGESFMPREDQDVVAYGITDLENKGIALHTNVETTELSSDNHHTTVHTNV
HCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEECCCCCEEEEEECC
GNFEADAVLLAIGRKPNTDLALENTDIELGDRGEIKVNAHLQTTVPHIYAAGDVKGGLQF
CCCCCCEEEEEECCCCCCCEEEECCCEEECCCCCEEEEEEEEECCCEEEEECCCCCCEEE
TYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQ
EEEECCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCHHHHHHHCCCHHHH
LLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQSEELINIIKLAIDQNIPYTVL
HHHHHCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEE
RDNIYTHPTMAESFNDLFNF
ECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSPKMYGGTCINIGCIPSKTLVHDGLE
CCEEEEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHCCCC
GKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHDDIVDSI
CCCEECCCCCCHHHHHHHCCCCEEEEECCCCEEEEEEEEECCCCCEEEEECCCCHHHHHC
TAPHIIINTGATSVIPNIKGLDQAKHVFDSTGLLNISYQPKHLVIVGGGYIALEFASMFA
CCCEEEEECCCHHCCCCCCCCHHHHHHHCCCCEEEEEECCCEEEEECCCEEEHHHHHHHH
NLGSKVTVLERGESFMPREDQDVVAYGITDLENKGIALHTNVETTELSSDNHHTTVHTNV
HCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEECCCCCEEEEEECC
GNFEADAVLLAIGRKPNTDLALENTDIELGDRGEIKVNAHLQTTVPHIYAAGDVKGGLQF
CCCCCCEEEEEECCCCCCCEEEECCCEEECCCCCEEEEEEEEECCCEEEEECCCCCCEEE
TYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQ
EEEECCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCHHHHHHHCCCHHHH
LLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQSEELINIIKLAIDQNIPYTVL
HHHHHCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEE
RDNIYTHPTMAESFNDLFNF
ECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]