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The map label for this gene is argB

Identifier: 87201309

GI number: 87201309

Start: 3517962

End: 3518873

Strand: Direct

Name: argB

Synonym: Saro_3297

Alternate gene names: 87201309

Gene position: 3517962-3518873 (Clockwise)

Preceding gene: 87201308

Following gene: 87201310

Centisome position: 98.78

GC content: 67.54

Gene sequence:

>912_bases
ATGAGCCAGAACCACGACCCCGCAATGCTTGCCAAGGCCGAAACGCTGACCGAGGCGCTGCCCTATCTCCAGCGCTATGC
GGGCAAGACCTTCGTGGTGAAGTACGGCGGCCACGCGATGGGCGATCCCGAACTCGCGCAGGACTTCGCCGAAGATATCG
TGCTGCTCAAGGCCGTGGGCATCAACCCTGTCGTGGTCCACGGCGGCGGGCCCCAGATCGGTCGCATGCTCAAGGCGCTC
GGCATCGAATCGCGGTTCGTCGACGGCCTGCGCGTCACCGACAAGCAAACGGCCGAAGTCGCAGAAATGGTCCTCGCCGG
CGCGATCAACAAGGAACTGGTAAGCTGGATCGCCCGCGCGGGCGGCAAGGCCATCGGCATTTCCGGCAAGGACGGGGGCA
TGGTCATCGCCCGCAAGGTCGAGGCCAAGAAGGCGCCCAAGGCCGTGGCCGATGCTGAAAGCGGCGATCCCATCGTCGTC
GACCTCGGCTTCGTGGGCGAGCCCGACCGGATCGACACGACCGTCATCGACACGATCTGCAAGGCCGGCATGATCCCGGT
CATCGCCCCCATCGGCGTTGGCGAGGACGGCGAGACGTACAACATCAACGCCGACACGATGGCCGGCTCCATCGCCGCCG
CGCTGGGCGCCGCGCGCCTGTTCCTGCTGACCGACGTTCCCGGCGTGCTCGACAAGGACAAGAACCTGCTCACCGACCTT
CGCCCCGCCGACATCGCGCGGCTGGCCGAGGACGGCACGATCAGCGGCGGCATGATCCCGAAGCTGGAAACCTGCGTCCA
CGCGGTCGAGGCGGGCTGCGAGGCAACCGTCGTGCTCGACGGCCGCGTGCCCCACGCGATGCTCCTCGAAATCTTCACGG
CGCGCGGCGCGGGCACCCTGATCCGCGCCTGA

Upstream 100 bases:

>100_bases
GCTGGCCCCAGCGATGTAGCGCGACCTTGCCGCAGATCCTGCCGCGATCGCGCGATCAGCAATATTGGATTCCGCCTCCA
TTGCGCGTAAGGGCCCGCGC

Downstream 100 bases:

>100_bases
AGGCTGCATTAAAGACGGGAACCGGAAGGCGTGCCGCTCGTCAGTGCGGCATGATCCGCCCCTGTCGTCTCGCCGCGGCG
CTTGCTGCATTGCCGCTTGC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSQNHDPAMLAKAETLTEALPYLQRYAGKTFVVKYGGHAMGDPELAQDFAEDIVLLKAVGINPVVVHGGGPQIGRMLKAL
GIESRFVDGLRVTDKQTAEVAEMVLAGAINKELVSWIARAGGKAIGISGKDGGMVIARKVEAKKAPKAVADAESGDPIVV
DLGFVGEPDRIDTTVIDTICKAGMIPVIAPIGVGEDGETYNINADTMAGSIAAALGAARLFLLTDVPGVLDKDKNLLTDL
RPADIARLAEDGTISGGMIPKLETCVHAVEAGCEATVVLDGRVPHAMLLEIFTARGAGTLIRA

Sequences:

>Translated_303_residues
MSQNHDPAMLAKAETLTEALPYLQRYAGKTFVVKYGGHAMGDPELAQDFAEDIVLLKAVGINPVVVHGGGPQIGRMLKAL
GIESRFVDGLRVTDKQTAEVAEMVLAGAINKELVSWIARAGGKAIGISGKDGGMVIARKVEAKKAPKAVADAESGDPIVV
DLGFVGEPDRIDTTVIDTICKAGMIPVIAPIGVGEDGETYNINADTMAGSIAAALGAARLFLLTDVPGVLDKDKNLLTDL
RPADIARLAEDGTISGGMIPKLETCVHAVEAGCEATVVLDGRVPHAMLLEIFTARGAGTLIRA
>Mature_302_residues
SQNHDPAMLAKAETLTEALPYLQRYAGKTFVVKYGGHAMGDPELAQDFAEDIVLLKAVGINPVVVHGGGPQIGRMLKALG
IESRFVDGLRVTDKQTAEVAEMVLAGAINKELVSWIARAGGKAIGISGKDGGMVIARKVEAKKAPKAVADAESGDPIVVD
LGFVGEPDRIDTTVIDTICKAGMIPVIAPIGVGEDGETYNINADTMAGSIAAALGAARLFLLTDVPGVLDKDKNLLTDLR
PADIARLAEDGTISGGMIPKLETCVHAVEAGCEATVVLDGRVPHAMLLEIFTARGAGTLIRA

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=296, Percent_Identity=27.7027027027027, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693208, Length=239, Percent_Identity=28.8702928870293, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320913, Length=289, Percent_Identity=25.2595155709343, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_NOVAD (Q2G341)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_498566.1
- ProteinModelPortal:   Q2G341
- SMR:   Q2G341
- STRING:   Q2G341
- GeneID:   3915944
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_3297
- NMPDR:   fig|48935.1.peg.3895
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q2G341
- ProtClustDB:   PRK00942
- BioCyc:   NARO279238:SARO_3297-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31542; Mature: 31411

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: BINDING 91-91 BINDING 201-201

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNHDPAMLAKAETLTEALPYLQRYAGKTFVVKYGGHAMGDPELAQDFAEDIVLLKAVG
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHEECC
INPVVVHGGGPQIGRMLKALGIESRFVDGLRVTDKQTAEVAEMVLAGAINKELVSWIARA
CCEEEEECCCHHHHHHHHHHCCHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GGKAIGISGKDGGMVIARKVEAKKAPKAVADAESGDPIVVDLGFVGEPDRIDTTVIDTIC
CCCEEEECCCCCCEEEEEEHHHHHCCCHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
KAGMIPVIAPIGVGEDGETYNINADTMAGSIAAALGAARLFLLTDVPGVLDKDKNLLTDL
HCCCCEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHCC
RPADIARLAEDGTISGGMIPKLETCVHAVEAGCEATVVLDGRVPHAMLLEIFTARGAGTL
CHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCC
IRA
CCC
>Mature Secondary Structure 
SQNHDPAMLAKAETLTEALPYLQRYAGKTFVVKYGGHAMGDPELAQDFAEDIVLLKAVG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHEECC
INPVVVHGGGPQIGRMLKALGIESRFVDGLRVTDKQTAEVAEMVLAGAINKELVSWIARA
CCEEEEECCCHHHHHHHHHHCCHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GGKAIGISGKDGGMVIARKVEAKKAPKAVADAESGDPIVVDLGFVGEPDRIDTTVIDTIC
CCCEEEECCCCCCEEEEEEHHHHHCCCHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
KAGMIPVIAPIGVGEDGETYNINADTMAGSIAAALGAARLFLLTDVPGVLDKDKNLLTDL
HCCCCEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHCC
RPADIARLAEDGTISGGMIPKLETCVHAVEAGCEATVVLDGRVPHAMLLEIFTARGAGTL
CHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCC
IRA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA