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The map label for this gene is uppP

Identifier: 87201196

GI number: 87201196

Start: 3405807

End: 3406619

Strand: Direct

Name: uppP

Synonym: Saro_3184

Alternate gene names: 87201196

Gene position: 3405807-3406619 (Clockwise)

Preceding gene: 87201195

Following gene: 87201197

Centisome position: 95.63

GC content: 65.56

Gene sequence:

>813_bases
ATGGACACGATCGTAACCGCAATCCTGCTCGGCATCGTCGAGGGCCTCACCGAATTCCTGCCCGTCTCATCGACCGGCCA
CCTGATCCTTGCAACCGAGCTGTTCGGCTATGACGCGCACCAGTGGGCGATGTTCAACGTCGTGATCCAGCTTGGCGCGA
TCCTGGCGGTGGTGGTCCAGTACTGGCGGACGTTCTGGGCGGTCGGCATGGGCCTGCTCAGGCTTGAGCCGATCTCCCTG
CGGTTCTTGCGCAACCTTCTGGCGGCGTTCATCCCGTCCGCAATCCTTGGCCTGGCGCTCAAGAAATACATCGATGTCCT
GCTCGGCAGCCCGTCGGTGGTGTGCTGGGCGCTGATTGCGGGCGGCATCGCGATCCTCGTGATCGAGAAACACGCAAAGC
AGGGCGAGCCATCGGGGATCGGACAGCTTCCACTGCGGCAGGCGATTGGCGTCGGCCTTGCGCAGTGCCTTGCGATGGTG
CCGGGCGTCAGCCGATCGGGCGCGACCATCATGGGCGCTCTGGCGATGGGCATCGAGCGCCGCACGGCGGCCGAGTTCAG
CTTCTTCCTCGCGATCCCGACGATGCTCGGTGCCACGACGCTCGAACTGCTCGACAACCGCGACGCGCTGCTCGGCGGCA
CGATGGGCGTTGGCTGGAGCGAGATCGGCGTCGGCTTTGCGGTGTCCTTCGTGGTTGCGCTCGCGGTCATCCGACTGTTC
GTCGCCTATGTCAGCCGCGCCGGGTTCAAACCTTTCGCGTGGTACCGCATTGCCGCCGGCGCAGTGGCGCTCGGCTGGCT
GGCGATGCGCTGA

Upstream 100 bases:

>100_bases
GCCGCGTAACCGGGCACTCGTGACGGAGACGACGCTCCGGTCGAGAATGCACCCTTCCGCTTGACTTGATGCTGCGCCGC
GGCAAACCCCGAAGGCACGT

Downstream 100 bases:

>100_bases
CCGAAACAGGCCCCTTTCATCGACCCGCCGCATCTGCGGAACCAAGTGCCCCGTCCGGGATTGACCGAACAGACAGCACT
TCAAGGGGTTACTGAAATGG

Product: undecaprenyl-diphosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MDTIVTAILLGIVEGLTEFLPVSSTGHLILATELFGYDAHQWAMFNVVIQLGAILAVVVQYWRTFWAVGMGLLRLEPISL
RFLRNLLAAFIPSAILGLALKKYIDVLLGSPSVVCWALIAGGIAILVIEKHAKQGEPSGIGQLPLRQAIGVGLAQCLAMV
PGVSRSGATIMGALAMGIERRTAAEFSFFLAIPTMLGATTLELLDNRDALLGGTMGVGWSEIGVGFAVSFVVALAVIRLF
VAYVSRAGFKPFAWYRIAAGAVALGWLAMR

Sequences:

>Translated_270_residues
MDTIVTAILLGIVEGLTEFLPVSSTGHLILATELFGYDAHQWAMFNVVIQLGAILAVVVQYWRTFWAVGMGLLRLEPISL
RFLRNLLAAFIPSAILGLALKKYIDVLLGSPSVVCWALIAGGIAILVIEKHAKQGEPSGIGQLPLRQAIGVGLAQCLAMV
PGVSRSGATIMGALAMGIERRTAAEFSFFLAIPTMLGATTLELLDNRDALLGGTMGVGWSEIGVGFAVSFVVALAVIRLF
VAYVSRAGFKPFAWYRIAAGAVALGWLAMR
>Mature_270_residues
MDTIVTAILLGIVEGLTEFLPVSSTGHLILATELFGYDAHQWAMFNVVIQLGAILAVVVQYWRTFWAVGMGLLRLEPISL
RFLRNLLAAFIPSAILGLALKKYIDVLLGSPSVVCWALIAGGIAILVIEKHAKQGEPSGIGQLPLRQAIGVGLAQCLAMV
PGVSRSGATIMGALAMGIERRTAAEFSFFLAIPTMLGATTLELLDNRDALLGGTMGVGWSEIGVGFAVSFVVALAVIRLF
VAYVSRAGFKPFAWYRIAAGAVALGWLAMR

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=272, Percent_Identity=43.0147058823529, Blast_Score=183, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_NOVAD (Q2G3F4)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_498453.1
- STRING:   Q2G3F4
- GeneID:   3917442
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_3184
- NMPDR:   fig|48935.1.peg.3004
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- PhylomeDB:   Q2G3F4
- ProtClustDB:   CLSK2776066
- BioCyc:   NARO279238:SARO_3184-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28716; Mature: 28716

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x165c944c)-; HASH(0x18ad04bc)-; HASH(0x18ad03a8)-; HASH(0x18ad01bc)-; HASH(0x18e3ac4c)-; HASH(0x18f34bcc)-; HASH(0x18f5a2dc)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTIVTAILLGIVEGLTEFLPVSSTGHLILATELFGYDAHQWAMFNVVIQLGAILAVVVQ
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YWRTFWAVGMGLLRLEPISLRFLRNLLAAFIPSAILGLALKKYIDVLLGSPSVVCWALIA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GGIAILVIEKHAKQGEPSGIGQLPLRQAIGVGLAQCLAMVPGVSRSGATIMGALAMGIER
CCCEEEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RTAAEFSFFLAIPTMLGATTLELLDNRDALLGGTMGVGWSEIGVGFAVSFVVALAVIRLF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VAYVSRAGFKPFAWYRIAAGAVALGWLAMR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MDTIVTAILLGIVEGLTEFLPVSSTGHLILATELFGYDAHQWAMFNVVIQLGAILAVVVQ
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YWRTFWAVGMGLLRLEPISLRFLRNLLAAFIPSAILGLALKKYIDVLLGSPSVVCWALIA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GGIAILVIEKHAKQGEPSGIGQLPLRQAIGVGLAQCLAMVPGVSRSGATIMGALAMGIER
CCCEEEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RTAAEFSFFLAIPTMLGATTLELLDNRDALLGGTMGVGWSEIGVGFAVSFVVALAVIRLF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VAYVSRAGFKPFAWYRIAAGAVALGWLAMR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA