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The map label for this gene is wecB [H]

Identifier: 87201161

GI number: 87201161

Start: 3360447

End: 3361565

Strand: Reverse

Name: wecB [H]

Synonym: Saro_3149

Alternate gene names: 87201161

Gene position: 3361565-3360447 (Counterclockwise)

Preceding gene: 87201164

Following gene: 87201160

Centisome position: 94.38

GC content: 67.29

Gene sequence:

>1119_bases
ATGGTGAAGACGATACTCGTGGTGTTCGGGACGCGGCCCGAGGCGATCAAGCTGTTTCCGGTGGTGCACGCGCTGCGTGC
CGATCCGCGCTTTCGCGTGGTGACCTGCGTTTCGGCGCAGCACCGGGGGATGCTCGACCAGGTGCTGGAGATCGCGGGGA
TCGTGCCCGACCACGATCTCGACCTGATGCGGCCGGACCAGACGCTCGACGCGCTGACGGCGGCGCTTCTGACGGAACTG
GGCAAGGTGATGGATGCCGTGCGGCCCGACTGGGTCGTGGTCCAGGGCGATACGGCGACGGCGATGGCCGGGGCGCTGGC
GGCTTATTATCGCAAGCTTCCGGTCGCGCATGTCGAGGCGGGCCTGCGCAGCCACAACATCTATCACCCGTGGCCCGAGG
AGGTGAACCGCAAGATTATCGGCACGATCGCGCGGCTGCACTTCGCGCCGACCGAGGTATCGGCTGCCGCGCTCAGGGCG
GAGAACGTGACCGAGGGCGTTCACGTGACCGGCAACACGGTGATCGACGCCTTGCAGTGGGTTTCGGGCCGGATTGCGGC
GGAGCCGGCGCTGGCGGCGGGGCTGGCCGAGATCGAGGCGCGCTTTGCCGGCAAGCGGATCATCGGCGTAACCAGCCACC
GCCGCGAGAATTTCGGCGGGGGGCTTGAGAACATCGCCGAGGCGATCCGCCGCATCGCGCAGCGGGACGACGTGGCGCTG
GTCTTTCCGGTCCATCCCAACCCCAACGTGCGCAAGGTGATGGACGATGCGCTGGCGGGGCTGCCCAACGTCGCGATGAT
CGAGCCGCTCGACTATCCGCACTTCGCCCGGCTGTTGTCGATCGCGGAAATCATGCTGACCGATTCGGGAGGGGTGCAGG
AAGAGGCCCCCGCGCTCGGCAAGCCGGTGCTGGTCATGCGGGAGACGACCGAGCGCCCCGAGGGCGTGACCGCCGGGACC
GCGCGGCTGGTGGGGACCGACGTGGACACCATCGTTACCGAAATCTTCACCCTGCTCGACGATAAGGCTGCCTATTCGGC
CATGGCGCGCGCTCACAATCCCTTCGGGGATGGGCAATCTTCGCGCCGAATCGTGGAGTTGCTGGCGAATGATGGGTGA

Upstream 100 bases:

>100_bases
GCGGCCTTTCATGGTTGACGCGCATGCGCGCCGACTTTGCCGTCGGCTTAAAGCGAGGCTCTTATTTCACGGTTAACACT
CGCCGATTATTGGAGCGGGC

Downstream 100 bases:

>100_bases
TGTGAAGCCGGACGTCTGTGTCGTCGGCCTTGGCTATATCGGACTTCCCACCGCCGCCATCATTGCCCGCGCCGGCTGCC
GCGTGCTGGGCCTCGACGTT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MVKTILVVFGTRPEAIKLFPVVHALRADPRFRVVTCVSAQHRGMLDQVLEIAGIVPDHDLDLMRPDQTLDALTAALLTEL
GKVMDAVRPDWVVVQGDTATAMAGALAAYYRKLPVAHVEAGLRSHNIYHPWPEEVNRKIIGTIARLHFAPTEVSAAALRA
ENVTEGVHVTGNTVIDALQWVSGRIAAEPALAAGLAEIEARFAGKRIIGVTSHRRENFGGGLENIAEAIRRIAQRDDVAL
VFPVHPNPNVRKVMDDALAGLPNVAMIEPLDYPHFARLLSIAEIMLTDSGGVQEEAPALGKPVLVMRETTERPEGVTAGT
ARLVGTDVDTIVTEIFTLLDDKAAYSAMARAHNPFGDGQSSRRIVELLANDG

Sequences:

>Translated_372_residues
MVKTILVVFGTRPEAIKLFPVVHALRADPRFRVVTCVSAQHRGMLDQVLEIAGIVPDHDLDLMRPDQTLDALTAALLTEL
GKVMDAVRPDWVVVQGDTATAMAGALAAYYRKLPVAHVEAGLRSHNIYHPWPEEVNRKIIGTIARLHFAPTEVSAAALRA
ENVTEGVHVTGNTVIDALQWVSGRIAAEPALAAGLAEIEARFAGKRIIGVTSHRRENFGGGLENIAEAIRRIAQRDDVAL
VFPVHPNPNVRKVMDDALAGLPNVAMIEPLDYPHFARLLSIAEIMLTDSGGVQEEAPALGKPVLVMRETTERPEGVTAGT
ARLVGTDVDTIVTEIFTLLDDKAAYSAMARAHNPFGDGQSSRRIVELLANDG
>Mature_372_residues
MVKTILVVFGTRPEAIKLFPVVHALRADPRFRVVTCVSAQHRGMLDQVLEIAGIVPDHDLDLMRPDQTLDALTAALLTEL
GKVMDAVRPDWVVVQGDTATAMAGALAAYYRKLPVAHVEAGLRSHNIYHPWPEEVNRKIIGTIARLHFAPTEVSAAALRA
ENVTEGVHVTGNTVIDALQWVSGRIAAEPALAAGLAEIEARFAGKRIIGVTSHRRENFGGGLENIAEAIRRIAQRDDVAL
VFPVHPNPNVRKVMDDALAGLPNVAMIEPLDYPHFARLLSIAEIMLTDSGGVQEEAPALGKPVLVMRETTERPEGVTAGT
ARLVGTDVDTIVTEIFTLLDDKAAYSAMARAHNPFGDGQSSRRIVELLANDG

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=373, Percent_Identity=52.5469168900804, Blast_Score=373, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40196; Mature: 40196

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKTILVVFGTRPEAIKLFPVVHALRADPRFRVVTCVSAQHRGMLDQVLEIAGIVPDHDL
CCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECHHHCCHHHHHHHHHCCCCCCCC
DLMRPDQTLDALTAALLTELGKVMDAVRPDWVVVQGDTATAMAGALAAYYRKLPVAHVEA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHH
GLRSHNIYHPWPEEVNRKIIGTIARLHFAPTEVSAAALRAENVTEGVHVTGNTVIDALQW
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCHHHHHHHHH
VSGRIAAEPALAAGLAEIEARFAGKRIIGVTSHRRENFGGGLENIAEAIRRIAQRDDVAL
HHCCHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHCCCCHHHHHHHHHHHHCCCCEEE
VFPVHPNPNVRKVMDDALAGLPNVAMIEPLDYPHFARLLSIAEIMLTDSGGVQEEAPALG
EEECCCCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCC
KPVLVMRETTERPEGVTAGTARLVGTDVDTIVTEIFTLLDDKAAYSAMARAHNPFGDGQS
CCEEEEECCCCCCCCCCCCCHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCH
SRRIVELLANDG
HHHHHHHHHCCC
>Mature Secondary Structure
MVKTILVVFGTRPEAIKLFPVVHALRADPRFRVVTCVSAQHRGMLDQVLEIAGIVPDHDL
CCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECHHHCCHHHHHHHHHCCCCCCCC
DLMRPDQTLDALTAALLTELGKVMDAVRPDWVVVQGDTATAMAGALAAYYRKLPVAHVEA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHH
GLRSHNIYHPWPEEVNRKIIGTIARLHFAPTEVSAAALRAENVTEGVHVTGNTVIDALQW
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCHHHHHHHHH
VSGRIAAEPALAAGLAEIEARFAGKRIIGVTSHRRENFGGGLENIAEAIRRIAQRDDVAL
HHCCHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHCCCCHHHHHHHHHHHHCCCCEEE
VFPVHPNPNVRKVMDDALAGLPNVAMIEPLDYPHFARLLSIAEIMLTDSGGVQEEAPALG
EEECCCCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCC
KPVLVMRETTERPEGVTAGTARLVGTDVDTIVTEIFTLLDDKAAYSAMARAHNPFGDGQS
CCEEEEECCCCCCCCCCCCCHHEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCH
SRRIVELLANDG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]