Click here to switch to the map view.

The map label for this gene is erg3 [H]

Identifier: 87201157

GI number: 87201157

Start: 3354700

End: 3355593

Strand: Direct

Name: erg3 [H]

Synonym: Saro_3145

Alternate gene names: 87201157

Gene position: 3354700-3355593 (Clockwise)

Preceding gene: 87201156

Following gene: 87201159

Centisome position: 94.19

GC content: 66.11

Gene sequence:

>894_bases
ATGAAGCCGTTCGATGTCGTGACCTGGGCCGTGCCCTTCTTCGTGGTCATGGTCCTGGCCGAAATGATCTGGGCCGCGCG
CCGCCACCCCGAAAAGTACGAACCGCGCGACACGCTCACCAGCCTCGCGCTTGGTCTTGGCAGCACCATCGCGGGTGCAC
TGACCGCCGGCGCGGTCTTCGCCGCCGCGCTGTGGCTGTACGACCACCGCGTGGCGACCGTTCCCTTCGCATGGTGGGCC
TGGGCGCTGTGCTTCGTGCTCGACGATTTCAACTACTACCTTGCCCATCGCACCGGCCACCGCGTGCGATGGTTCTGGGC
AAGCCACGTCAACCACCACTCCAGCCAGCATTACAACCTGTCGACCGCCTTGCGGCAGACCTGGACCGGCTTCTTCGCAC
TGTCGTTCGTCTTCCGCATCTGGCCCGCTCTGATCGGCTTCCACCCGGCCATGATCGTGACGGTGGGCGGCGTGAATCTG
GTCTACCAGTTCTGGATCCATACCGAAGCGGTCGGGCGCTTGCCGCGCTGGTTCGAGGCGGTGTTCAACACCCCGTCGCA
CCACCGCGTCCACCACGCCACAAATCCGCTCTATCTCGACCGCAACTATGCCGGCGTGTTCATCGTCTGGGACCGCCTTT
TCGGCACCTTCCAGCCCGAGCGCGACGATCTGGCGATCCGCTATGGCATCGTCCGCCAGCTCGGCAGCTTCCACCTGCTC
CACGCCGCCTTCCACGAATGGCGTGCAATGCTCGGCGACTTCTGGCGCGCGCCGCTGCGCTACAAGCTGCACTATCTCGT
GCGCGCGCCCGGCTGGAGCCACGACGGCAGCCGCGAAGGCTCCGACGCCATCCGCGCGCGCTGGACCGAACGGCAGGGCC
TCAGCGGCGATTGA

Upstream 100 bases:

>100_bases
CCATCGCCACCGACGACACGCGCTTCGGCAAGGTAACCCTCGACCTCGGCGACCAGGCCCAGGTCTGGGCGGCAAGCCTG
CGCCGCCTCGGAGCCGGAGC

Downstream 100 bases:

>100_bases
GCCCTTCGCCCAGCAGATCGGCCGCCACTTCGGCGATCTCCTCGACCGGCCGGCTGTCGTCCCACACGCCATAGCGCAGG
CCCAGAAACACATTCATGCC

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKPFDVVTWAVPFFVVMVLAEMIWAARRHPEKYEPRDTLTSLALGLGSTIAGALTAGAVFAAALWLYDHRVATVPFAWWA
WALCFVLDDFNYYLAHRTGHRVRWFWASHVNHHSSQHYNLSTALRQTWTGFFALSFVFRIWPALIGFHPAMIVTVGGVNL
VYQFWIHTEAVGRLPRWFEAVFNTPSHHRVHHATNPLYLDRNYAGVFIVWDRLFGTFQPERDDLAIRYGIVRQLGSFHLL
HAAFHEWRAMLGDFWRAPLRYKLHYLVRAPGWSHDGSREGSDAIRARWTERQGLSGD

Sequences:

>Translated_297_residues
MKPFDVVTWAVPFFVVMVLAEMIWAARRHPEKYEPRDTLTSLALGLGSTIAGALTAGAVFAAALWLYDHRVATVPFAWWA
WALCFVLDDFNYYLAHRTGHRVRWFWASHVNHHSSQHYNLSTALRQTWTGFFALSFVFRIWPALIGFHPAMIVTVGGVNL
VYQFWIHTEAVGRLPRWFEAVFNTPSHHRVHHATNPLYLDRNYAGVFIVWDRLFGTFQPERDDLAIRYGIVRQLGSFHLL
HAAFHEWRAMLGDFWRAPLRYKLHYLVRAPGWSHDGSREGSDAIRARWTERQGLSGD
>Mature_297_residues
MKPFDVVTWAVPFFVVMVLAEMIWAARRHPEKYEPRDTLTSLALGLGSTIAGALTAGAVFAAALWLYDHRVATVPFAWWA
WALCFVLDDFNYYLAHRTGHRVRWFWASHVNHHSSQHYNLSTALRQTWTGFFALSFVFRIWPALIGFHPAMIVTVGGVNL
VYQFWIHTEAVGRLPRWFEAVFNTPSHHRVHHATNPLYLDRNYAGVFIVWDRLFGTFQPERDDLAIRYGIVRQLGSFHLL
HAAFHEWRAMLGDFWRAPLRYKLHYLVRAPGWSHDGSREGSDAIRARWTERQGLSGD

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=288, Percent_Identity=35.0694444444444, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI25144659, Length=256, Percent_Identity=34.765625, Blast_Score=143, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 34459; Mature: 34459

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFDVVTWAVPFFVVMVLAEMIWAARRHPEKYEPRDTLTSLALGLGSTIAGALTAGAVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAALWLYDHRVATVPFAWWAWALCFVLDDFNYYLAHRTGHRVRWFWASHVNHHSSQHYNL
HHHHHHHHCCCEECCHHHHHHHHHHHHHCCHHEEEECCCCEEEEEEEHHCCCCCCCCCHH
STALRQTWTGFFALSFVFRIWPALIGFHPAMIVTVGGVNLVYQFWIHTEAVGRLPRWFEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHH
VFNTPSHHRVHHATNPLYLDRNYAGVFIVWDRLFGTFQPERDDLAIRYGIVRQLGSFHLL
HHCCCCCCEEECCCCCEEEECCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
HAAFHEWRAMLGDFWRAPLRYKLHYLVRAPGWSHDGSREGSDAIRARWTERQGLSGD
HHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKPFDVVTWAVPFFVVMVLAEMIWAARRHPEKYEPRDTLTSLALGLGSTIAGALTAGAVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAALWLYDHRVATVPFAWWAWALCFVLDDFNYYLAHRTGHRVRWFWASHVNHHSSQHYNL
HHHHHHHHCCCEECCHHHHHHHHHHHHHCCHHEEEECCCCEEEEEEEHHCCCCCCCCCHH
STALRQTWTGFFALSFVFRIWPALIGFHPAMIVTVGGVNLVYQFWIHTEAVGRLPRWFEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHH
VFNTPSHHRVHHATNPLYLDRNYAGVFIVWDRLFGTFQPERDDLAIRYGIVRQLGSFHLL
HHCCCCCCEEECCCCCEEEECCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
HAAFHEWRAMLGDFWRAPLRYKLHYLVRAPGWSHDGSREGSDAIRARWTERQGLSGD
HHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]