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The map label for this gene is mcpA [H]

Identifier: 87200834

GI number: 87200834

Start: 3044321

End: 3046384

Strand: Direct

Name: mcpA [H]

Synonym: Saro_2821

Alternate gene names: 87200834

Gene position: 3044321-3046384 (Clockwise)

Preceding gene: 87200833

Following gene: 87200835

Centisome position: 85.48

GC content: 68.7

Gene sequence:

>2064_bases
ATGTTCAAGTTCAATATCTCGGCCAAGTTCATATCCGCATTTGCGCTGCTTCTGGCGGTGATGGCGGGCATGGGGCTCTT
TGCCGTATCGAAGATCGGTGAAGTCAACGTCATCGCGGCGGAGCAGCGGGACCGCTGGATGCCCGCCGCAGCCACGCTGG
GTGATATCCACGCCTTCACGTCGCAATACCGCCTCAAGCAGGACGAGATGCTCAACGCCACCTCGCCGGCGGCGATGGAG
CGCAGCCAGAAGCTCATGCGCAACGCACGGGCTGCCATCGACGACAGCCTGGCCCAGTTCGAAAAGCTCGCTTCGACGCC
CGAACAGAAGGGCGCGGTCGCCACGATCAGGGAATCATGGGCTCGCCTGCTTGAACAGGACCAGACCATGCAGGCCATGG
CGCTTTCGGGCGACCAGGCCGGCGCACAGGCCATGCACAACAGCGAAGGCCTCGATTCCTTCTACGCCGTCGAGGACGCC
ATCCTCGCCGCGATCGAGGTCAACCAGAAGGCCGCGGATGCCGTCTCCGCCCAGAGCGAGGAAATCTACGCCTCGGCGCG
GACCTTCACCTTCGGCATCATCGGCCTCGGCCTGCTCGCGGCGCTTTCCCTGCTCGTCTTCCTCATGCGCAACATCGCCC
GCCCCCTCGTCAACATGTCGGAAGCGGTTGTCCGCCTGACCTCCGGCGACCACAGCATCGCCGTTCCGGGCCTGGGCCGC
ACCGACGAGCTGGGCAGCCTGGCCCGCGCGCTCGACCAGTTCCGCGATGTCTTCGCCTCCGATCACGCCCGCGCCGAAAC
AGAAAAGGCCCGCGCGCGCGAGACGCAGGTCACCATCGACGCCATCGGTAGCGGCCTCACCGCCCTGGCCGAAGGCGACC
TCACCTTCCGCGTGGCCGAGAACGGCAGCGGCGCCCTTGCCAAGCTCCATGTCGACTACAACGCCGCCGTCGCCTCGCTC
GAACGCGTGCTCGGCAAGATCGTCGACGGCTGCAACACCATCAAGCTCGGCACCGACGAAATCGCCAGCGCCGCGACGGA
CCTTGCCCTGCGCACCGAACAGCAGGCCACCTCGCTTGCCGAAACCTCGCGCACGCTCAGCGAATTCACCGGCTCGGTGA
AGACCACCGCCGACAACGCGCGCCAGACGAGTTCGCGCCTGACCGTCGCGCGCAACACCGCGGACAGCGTGGGCGATACC
GCCAACCGCGCGGTCGCCGCCATGCGCTCCATCGAAAGCAGCTCACGCGAGATGGCAGAGATTGTCGGCGTGATCGATGG
CATCGCCTTCCAGACCAACCTGCTCGCGCTCAATGCCGGGGTCGAGGCCGCCCGCGCGGGCGATGCCGGCAAGGGCTTCG
CGGTCGTCGCCACCGAAGTGCGCGCGCTCGCCCAGCGCTCGGCCGATGCCGCGCGCTCGATCCGCGACCTCATCGGCAAG
AGCACCGACGAGATCAGCGGCGGCGTCGCGCTGGTGGAATCCAGCGGCGAGGCGCTGCGTCAGATCGTCACCGAAGTCAG
CGCCGTCTCGGCCCTGGTCGAGGAGATCGCCGAAGCGGCAGGCCAGCAGGCCGCCGGCATTGCCGACATCTCGGCCATGG
TCGGCTCGATGGACGCCTTCACCCAGCAGAACGCGGCCATGGTCGAGGAAAGCTCGGCCGGAACCCGCAACCTTGCCTCG
GAAACGCTTTCGCTGGTCGACCAGCTCGGGCGCTTCCGGCTCGCCACGGTCGGACAGGCTGCGGAGGACCGGTTCGAAGA
CGCGCCCGCCCCGGCCCGTCATTCCGGCTTCGGCGCCTTCGACGCGTTCGACGCGGCCCAGGTCGACGATTCCGACGAAG
CCCCGGCCTTGAGATCGCCCTCCTCGTACGAACCGGTGGCAATCGCCGATGAGCGCCCCCGGCCAGCCGCCCCGGTCGCC
GCCCCGGTCGCCGCTCCGCCTCCGCCTCCGGCCCCGGCCCCGGCCCCGCCTCCCCCGCCGGCAAAGCCACGGGCGGCCCG
CGCGGCACCTTCGCGTGGCGGCGCAGCGGTCAAGCTCGACGAGGACGACTGGTCGGAATTCTGA

Upstream 100 bases:

>100_bases
GCACCCCGACTGCGCACCAATACGGGCCACCAGCCTTACCTAAGATTCCATTCCCCTCGCTACGACAGGCAGCGTGCCGA
CAGGCTTTCGGGGAATGAAA

Downstream 100 bases:

>100_bases
CCACCACATCCAGATCATGAAAACCCAGCAGCACCTAAGGAAGTAAAGCCATGAAGACATTTGCACGACTTGCTCTCGGC
GTAACTGCGCTGGCGCTCTC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MFKFNISAKFISAFALLLAVMAGMGLFAVSKIGEVNVIAAEQRDRWMPAAATLGDIHAFTSQYRLKQDEMLNATSPAAME
RSQKLMRNARAAIDDSLAQFEKLASTPEQKGAVATIRESWARLLEQDQTMQAMALSGDQAGAQAMHNSEGLDSFYAVEDA
ILAAIEVNQKAADAVSAQSEEIYASARTFTFGIIGLGLLAALSLLVFLMRNIARPLVNMSEAVVRLTSGDHSIAVPGLGR
TDELGSLARALDQFRDVFASDHARAETEKARARETQVTIDAIGSGLTALAEGDLTFRVAENGSGALAKLHVDYNAAVASL
ERVLGKIVDGCNTIKLGTDEIASAATDLALRTEQQATSLAETSRTLSEFTGSVKTTADNARQTSSRLTVARNTADSVGDT
ANRAVAAMRSIESSSREMAEIVGVIDGIAFQTNLLALNAGVEAARAGDAGKGFAVVATEVRALAQRSADAARSIRDLIGK
STDEISGGVALVESSGEALRQIVTEVSAVSALVEEIAEAAGQQAAGIADISAMVGSMDAFTQQNAAMVEESSAGTRNLAS
ETLSLVDQLGRFRLATVGQAAEDRFEDAPAPARHSGFGAFDAFDAAQVDDSDEAPALRSPSSYEPVAIADERPRPAAPVA
APVAAPPPPPAPAPAPPPPPAKPRAARAAPSRGGAAVKLDEDDWSEF

Sequences:

>Translated_687_residues
MFKFNISAKFISAFALLLAVMAGMGLFAVSKIGEVNVIAAEQRDRWMPAAATLGDIHAFTSQYRLKQDEMLNATSPAAME
RSQKLMRNARAAIDDSLAQFEKLASTPEQKGAVATIRESWARLLEQDQTMQAMALSGDQAGAQAMHNSEGLDSFYAVEDA
ILAAIEVNQKAADAVSAQSEEIYASARTFTFGIIGLGLLAALSLLVFLMRNIARPLVNMSEAVVRLTSGDHSIAVPGLGR
TDELGSLARALDQFRDVFASDHARAETEKARARETQVTIDAIGSGLTALAEGDLTFRVAENGSGALAKLHVDYNAAVASL
ERVLGKIVDGCNTIKLGTDEIASAATDLALRTEQQATSLAETSRTLSEFTGSVKTTADNARQTSSRLTVARNTADSVGDT
ANRAVAAMRSIESSSREMAEIVGVIDGIAFQTNLLALNAGVEAARAGDAGKGFAVVATEVRALAQRSADAARSIRDLIGK
STDEISGGVALVESSGEALRQIVTEVSAVSALVEEIAEAAGQQAAGIADISAMVGSMDAFTQQNAAMVEESSAGTRNLAS
ETLSLVDQLGRFRLATVGQAAEDRFEDAPAPARHSGFGAFDAFDAAQVDDSDEAPALRSPSSYEPVAIADERPRPAAPVA
APVAAPPPPPAPAPAPPPPPAKPRAARAAPSRGGAAVKLDEDDWSEF
>Mature_687_residues
MFKFNISAKFISAFALLLAVMAGMGLFAVSKIGEVNVIAAEQRDRWMPAAATLGDIHAFTSQYRLKQDEMLNATSPAAME
RSQKLMRNARAAIDDSLAQFEKLASTPEQKGAVATIRESWARLLEQDQTMQAMALSGDQAGAQAMHNSEGLDSFYAVEDA
ILAAIEVNQKAADAVSAQSEEIYASARTFTFGIIGLGLLAALSLLVFLMRNIARPLVNMSEAVVRLTSGDHSIAVPGLGR
TDELGSLARALDQFRDVFASDHARAETEKARARETQVTIDAIGSGLTALAEGDLTFRVAENGSGALAKLHVDYNAAVASL
ERVLGKIVDGCNTIKLGTDEIASAATDLALRTEQQATSLAETSRTLSEFTGSVKTTADNARQTSSRLTVARNTADSVGDT
ANRAVAAMRSIESSSREMAEIVGVIDGIAFQTNLLALNAGVEAARAGDAGKGFAVVATEVRALAQRSADAARSIRDLIGK
STDEISGGVALVESSGEALRQIVTEVSAVSALVEEIAEAAGQQAAGIADISAMVGSMDAFTQQNAAMVEESSAGTRNLAS
ETLSLVDQLGRFRLATVGQAAEDRFEDAPAPARHSGFGAFDAFDAAQVDDSDEAPALRSPSSYEPVAIADERPRPAAPVA
APVAAPPPPPAPAPAPPPPPAKPRAARAAPSRGGAAVKLDEDDWSEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=256, Percent_Identity=46.875, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1788195, Length=287, Percent_Identity=43.9024390243902, Blast_Score=201, Evalue=2e-52,
Organism=Escherichia coli, GI1787690, Length=296, Percent_Identity=40.5405405405405, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1788194, Length=293, Percent_Identity=39.9317406143345, Blast_Score=192, Evalue=7e-50,
Organism=Escherichia coli, GI1789453, Length=370, Percent_Identity=30.2702702702703, Blast_Score=146, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 71769; Mature: 71769

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFNISAKFISAFALLLAVMAGMGLFAVSKIGEVNVIAAEQRDRWMPAAATLGDIHAFT
CEEECCHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHH
SQYRLKQDEMLNATSPAAMERSQKLMRNARAAIDDSLAQFEKLASTPEQKGAVATIRESW
HHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHH
ARLLEQDQTMQAMALSGDQAGAQAMHNSEGLDSFYAVEDAILAAIEVNQKAADAVSAQSE
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCHH
EIYASARTFTFGIIGLGLLAALSLLVFLMRNIARPLVNMSEAVVRLTSGDHSIAVPGLGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCCCC
TDELGSLARALDQFRDVFASDHARAETEKARARETQVTIDAIGSGLTALAEGDLTFRVAE
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEHHHHCCCHHEEECCCEEEEEEC
NGSGALAKLHVDYNAAVASLERVLGKIVDGCNTIKLGTDEIASAATDLALRTEQQATSLA
CCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
ETSRTLSEFTGSVKTTADNARQTSSRLTVARNTADSVGDTANRAVAAMRSIESSSREMAE
HHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
IVGVIDGIAFQTNLLALNAGVEAARAGDAGKGFAVVATEVRALAQRSADAARSIRDLIGK
HHHHHHHHHHHHHEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
STDEISGGVALVESSGEALRQIVTEVSAVSALVEEIAEAAGQQAAGIADISAMVGSMDAF
CCHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHH
TQQNAAMVEESSAGTRNLASETLSLVDQLGRFRLATVGQAAEDRFEDAPAPARHSGFGAF
HHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHCCCCCCCCCCCCCCC
DAFDAAQVDDSDEAPALRSPSSYEPVAIADERPRPAAPVAAPVAAPPPPPAPAPAPPPPP
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AKPRAARAAPSRGGAAVKLDEDDWSEF
CCCCCCCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MFKFNISAKFISAFALLLAVMAGMGLFAVSKIGEVNVIAAEQRDRWMPAAATLGDIHAFT
CEEECCHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHH
SQYRLKQDEMLNATSPAAMERSQKLMRNARAAIDDSLAQFEKLASTPEQKGAVATIRESW
HHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHH
ARLLEQDQTMQAMALSGDQAGAQAMHNSEGLDSFYAVEDAILAAIEVNQKAADAVSAQSE
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCHH
EIYASARTFTFGIIGLGLLAALSLLVFLMRNIARPLVNMSEAVVRLTSGDHSIAVPGLGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCCCC
TDELGSLARALDQFRDVFASDHARAETEKARARETQVTIDAIGSGLTALAEGDLTFRVAE
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEHHHHCCCHHEEECCCEEEEEEC
NGSGALAKLHVDYNAAVASLERVLGKIVDGCNTIKLGTDEIASAATDLALRTEQQATSLA
CCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
ETSRTLSEFTGSVKTTADNARQTSSRLTVARNTADSVGDTANRAVAAMRSIESSSREMAE
HHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
IVGVIDGIAFQTNLLALNAGVEAARAGDAGKGFAVVATEVRALAQRSADAARSIRDLIGK
HHHHHHHHHHHHHEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
STDEISGGVALVESSGEALRQIVTEVSAVSALVEEIAEAAGQQAAGIADISAMVGSMDAF
CCHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHH
TQQNAAMVEESSAGTRNLASETLSLVDQLGRFRLATVGQAAEDRFEDAPAPARHSGFGAF
HHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHCHHHHHHHCCCCCCCCCCCCCCC
DAFDAAQVDDSDEAPALRSPSSYEPVAIADERPRPAAPVAAPVAAPPPPPAPAPAPPPPP
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AKPRAARAAPSRGGAAVKLDEDDWSEF
CCCCCCCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]