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The map label for this gene is ucpA [C]

Identifier: 87200813

GI number: 87200813

Start: 3023603

End: 3024439

Strand: Reverse

Name: ucpA [C]

Synonym: Saro_2800

Alternate gene names: 87200813

Gene position: 3024439-3023603 (Counterclockwise)

Preceding gene: 87200814

Following gene: 87200811

Centisome position: 84.92

GC content: 66.07

Gene sequence:

>837_bases
ATGAGCGGACATATCGCGGGCAAGTCCATTGTCATCACCGGCGCGGGCGGCGGCTTCGGCTCGCTTGTCGCGCGCAAGGC
GGCGGCGCTGGGCGCGGCTGTCACCTGCGGCGACATCAACCTGGTCGCGGCACAGGCCGTTGCAGACGGGATCGCGGCCG
AAGGAGGCCGCGCGCAGGCGGTCGAAGTGGACGTGACCAGCCTGCCCGCGGTCAAGGAGCTCGTTGCCCGCGCGCTCGAT
GCGTTCGGCGCGGTGGACGTCATGGTCAACAATGCCGGCATCATGCCGCTGGCGTTCTTCTCGGACCACGAGGCGGCCTA
TCCTGCGTGGGAGCGCTGCATCGACATCAACATCAAGGGCGTGCTGAACGGCATGGTCGCGGCCTACGATCCGATGATCG
CGGCGGGGCGCGGGCAGATCGTCAATATCTCCTCGATCTACGGCAATTTCCCGGTGATCGGCGCGGCGGTCTATGGCGCG
TCGAAATCGGCGGTGAACTTCCTGTCGGAATCGCTGCGCGTGGAAAGTCGCGGAAAGATCAAGGTGACGACGATCAAGCC
TACCGGGGTGCCGACCACGGGCCTGTCGGGCACGGTCGTCAACCAGGCGGCCGGGATCGGGATCGTCGCTCACAACATGC
CCGATTTCATGGAAATGGTCGGGCAGATGGCGGAAGGCACCTTCCCGGCAGAGCGGCTCGATCCCGAGGCGATGGACTAT
GCCAGCCTCGCGCCCGAACATATCGCCGATGCGGTCATCCACGCGATCGACCAGCCCTGGGGCGTCTCGATCTCGGAGGT
CACCGTTCGCGCGGCGGGAGATCACTTCGTCCTGTGA

Upstream 100 bases:

>100_bases
GGCCGCGAAGGCGGGCCGGAAGGGCTCTTCCCCTATCTCGAAATGAAGACCATCCTGATTGATGGCATGCCTTCGGCGCT
TTGAAGGTACGGGAGAGAAC

Downstream 100 bases:

>100_bases
GCGGATGCCTGAACGGAAAACCCCCGCCGGTGAGGGCGGGGGCTTCGAGTTCCGGCCGCGGTGCCGATCACCTGATCGGG
CAGTCCGGCGACAGGCGCAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSGHIAGKSIVITGAGGGFGSLVARKAAALGAAVTCGDINLVAAQAVADGIAAEGGRAQAVEVDVTSLPAVKELVARALD
AFGAVDVMVNNAGIMPLAFFSDHEAAYPAWERCIDINIKGVLNGMVAAYDPMIAAGRGQIVNISSIYGNFPVIGAAVYGA
SKSAVNFLSESLRVESRGKIKVTTIKPTGVPTTGLSGTVVNQAAGIGIVAHNMPDFMEMVGQMAEGTFPAERLDPEAMDY
ASLAPEHIADAVIHAIDQPWGVSISEVTVRAAGDHFVL

Sequences:

>Translated_278_residues
MSGHIAGKSIVITGAGGGFGSLVARKAAALGAAVTCGDINLVAAQAVADGIAAEGGRAQAVEVDVTSLPAVKELVARALD
AFGAVDVMVNNAGIMPLAFFSDHEAAYPAWERCIDINIKGVLNGMVAAYDPMIAAGRGQIVNISSIYGNFPVIGAAVYGA
SKSAVNFLSESLRVESRGKIKVTTIKPTGVPTTGLSGTVVNQAAGIGIVAHNMPDFMEMVGQMAEGTFPAERLDPEAMDY
ASLAPEHIADAVIHAIDQPWGVSISEVTVRAAGDHFVL
>Mature_277_residues
SGHIAGKSIVITGAGGGFGSLVARKAAALGAAVTCGDINLVAAQAVADGIAAEGGRAQAVEVDVTSLPAVKELVARALDA
FGAVDVMVNNAGIMPLAFFSDHEAAYPAWERCIDINIKGVLNGMVAAYDPMIAAGRGQIVNISSIYGNFPVIGAAVYGAS
KSAVNFLSESLRVESRGKIKVTTIKPTGVPTTGLSGTVVNQAAGIGIVAHNMPDFMEMVGQMAEGTFPAERLDPEAMDYA
SLAPEHIADAVIHAIDQPWGVSISEVTVRAAGDHFVL

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=198, Percent_Identity=34.3434343434343, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI40807363, Length=201, Percent_Identity=32.8358208955224, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI150247226, Length=262, Percent_Identity=28.2442748091603, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI31542939, Length=168, Percent_Identity=30.952380952381, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI7705925, Length=195, Percent_Identity=31.2820512820513, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI224922801, Length=168, Percent_Identity=30.952380952381, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4504503, Length=201, Percent_Identity=28.3582089552239, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=32.9896907216495, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87082100, Length=238, Percent_Identity=34.453781512605, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=31.8435754189944, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790717, Length=226, Percent_Identity=29.646017699115, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787335, Length=208, Percent_Identity=31.25, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788459, Length=194, Percent_Identity=30.4123711340206, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082160, Length=227, Percent_Identity=27.3127753303965, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787905, Length=205, Percent_Identity=30.7317073170732, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789208, Length=185, Percent_Identity=30.2702702702703, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=30.2564102564103, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=187, Percent_Identity=32.620320855615, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=244, Percent_Identity=32.3770491803279, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=208, Percent_Identity=29.8076923076923, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=27.5132275132275, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=26.6917293233083, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=27.1356783919598, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=203, Percent_Identity=26.6009852216749, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=171, Percent_Identity=30.9941520467836, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=225, Percent_Identity=27.5555555555556, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=202, Percent_Identity=33.1683168316832, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=30.1980198019802, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=32.4742268041237, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281364892, Length=267, Percent_Identity=28.8389513108614, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649181, Length=208, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357041, Length=194, Percent_Identity=32.9896907216495, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639444, Length=199, Percent_Identity=34.6733668341709, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24643142, Length=195, Percent_Identity=31.7948717948718, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28571526, Length=182, Percent_Identity=29.6703296703297, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI23397609, Length=190, Percent_Identity=28.9473684210526, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644339, Length=219, Percent_Identity=28.310502283105, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI18859837, Length=198, Percent_Identity=32.8282828282828, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641388, Length=278, Percent_Identity=27.3381294964029, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17737361, Length=188, Percent_Identity=31.9148936170213, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581726, Length=199, Percent_Identity=29.1457286432161, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=25.8620689655172, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28430; Mature: 28299

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGHIAGKSIVITGAGGGFGSLVARKAAALGAAVTCGDINLVAAQAVADGIAAEGGRAQA
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCCCEE
VEVDVTSLPAVKELVARALDAFGAVDVMVNNAGIMPLAFFSDHEAAYPAWERCIDINIKG
EEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCHHHHEEEEEHHH
VLNGMVAAYDPMIAAGRGQIVNISSIYGNFPVIGAAVYGASKSAVNFLSESLRVESRGKI
HHHHHHHHHCCEEECCCCCEEEEHHHCCCCCEEEHEECCCCHHHHHHHHHHHEECCCCCE
KVTTIKPTGVPTTGLSGTVVNQAAGIGIVAHNMPDFMEMVGQMAEGTFPAERLDPEAMDY
EEEEECCCCCCCCCCCCCCHHHCCCCEEEECCCHHHHHHHHHHHCCCCCHHHCCHHHHHH
ASLAPEHIADAVIHAIDQPWGVSISEVTVRAAGDHFVL
HHCCHHHHHHHHHHHHCCCCCCCHHHEEEEECCCCCCC
>Mature Secondary Structure 
SGHIAGKSIVITGAGGGFGSLVARKAAALGAAVTCGDINLVAAQAVADGIAAEGGRAQA
CCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCCCEE
VEVDVTSLPAVKELVARALDAFGAVDVMVNNAGIMPLAFFSDHEAAYPAWERCIDINIKG
EEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCHHHHEEEEEHHH
VLNGMVAAYDPMIAAGRGQIVNISSIYGNFPVIGAAVYGASKSAVNFLSESLRVESRGKI
HHHHHHHHHCCEEECCCCCEEEEHHHCCCCCEEEHEECCCCHHHHHHHHHHHEECCCCCE
KVTTIKPTGVPTTGLSGTVVNQAAGIGIVAHNMPDFMEMVGQMAEGTFPAERLDPEAMDY
EEEEECCCCCCCCCCCCCCHHHCCCCEEEECCCHHHHHHHHHHHCCCCCHHHCCHHHHHH
ASLAPEHIADAVIHAIDQPWGVSISEVTVRAAGDHFVL
HHCCHHHHHHHHHHHHCCCCCCCHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1905979; 11679669 [H]