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The map label for this gene is blaA [H]

Identifier: 87200672

GI number: 87200672

Start: 2897751

End: 2898548

Strand: Reverse

Name: blaA [H]

Synonym: Saro_2659

Alternate gene names: 87200672

Gene position: 2898548-2897751 (Counterclockwise)

Preceding gene: 87200673

Following gene: 87200671

Centisome position: 81.38

GC content: 68.8

Gene sequence:

>798_bases
ATGAAACGGACGCACCTTCCGCTGAACGGCCTGCGCGTGCTCGATGCCGCGGCGCGCCACCTTTCGTTTACCCGCGCAGC
CGACGAGCTTGCGGTCACGCCGGCGGCTGTCGGCCAGCAGATTCGCGCCCTCGAGGATTTGCTGGGCGTCGTTCTGTTCC
GCCGGACGTCGAAAGGCCTGGAGCTGACCGACGAGGCGAGCGCGGGGCTTGATGCGATCCGCGAAGGCTTCCTGCGCTTC
GAGGAAGGCGTGCAGGCCATGCAGGCCGGCCAGTCGAGCCACGTGTACACCATTGCGTGCCCCCGCGATTTCTTCGCTGC
CTGGCTTTCGCCGAGGCTCGCCGATTTTCGCGCCGGGAACCCGCAGATGCGGTTTTCGCTGGTGGGCGGCGATGCCGACG
TCGACTTTACCGAGGCGAACCTCGACCTGGCGGTGCGTTGGGCCGAGGGGCCGGGGGACCTTGAAGGCGTGTCGCTCGGT
GCAGCAACCATGATCACGGTCGCCGCCCCGGATGCCGCACCGGATAGCCCGTGGATCGGCTGGCCGGGCGACCCGACGCC
GGAAGGTGGCGAGGCGGGCTTTTCGGTCGGTGATGCAGGGACCGCCATCAGTGCCGCCCGTGCAGGGCTTGGCCGGGCGA
ACGTGCCCTTCATGCTCGCCGAAGGCCCTCTTTCGTCGGGGCGCATAGTGGCGCTTGGCGAACCGCAGGTTTCGCGGCGC
GGATACTGGCTGGTCGCGCCTCCTCCGCAGTGGCGCCAGAAGAAGGTCAAGGCGCTCGTCGCCGCGCTGTCCTCCTGA

Upstream 100 bases:

>100_bases
CCATTACACGATGCAGCGTGCCGATGGGGCGCTGTTCGACGTGGCGATTCCGTTCTTTCCTCTGGCGGCACCGGCTCCGG
CAAACTAACGACGTCCTTCG

Downstream 100 bases:

>100_bases
CATATCGGGCCTTGCCCTTACGCCCTGTTAACCCCGTCGGCGTATGGCTCTGCAAATGGCGACGGGTTCACGATTTTTCT
CTACGCTCCAAAGGGGAAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Beta-lactamase regulatory protein BlaA [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKRTHLPLNGLRVLDAAARHLSFTRAADELAVTPAAVGQQIRALEDLLGVVLFRRTSKGLELTDEASAGLDAIREGFLRF
EEGVQAMQAGQSSHVYTIACPRDFFAAWLSPRLADFRAGNPQMRFSLVGGDADVDFTEANLDLAVRWAEGPGDLEGVSLG
AATMITVAAPDAAPDSPWIGWPGDPTPEGGEAGFSVGDAGTAISAARAGLGRANVPFMLAEGPLSSGRIVALGEPQVSRR
GYWLVAPPPQWRQKKVKALVAALSS

Sequences:

>Translated_265_residues
MKRTHLPLNGLRVLDAAARHLSFTRAADELAVTPAAVGQQIRALEDLLGVVLFRRTSKGLELTDEASAGLDAIREGFLRF
EEGVQAMQAGQSSHVYTIACPRDFFAAWLSPRLADFRAGNPQMRFSLVGGDADVDFTEANLDLAVRWAEGPGDLEGVSLG
AATMITVAAPDAAPDSPWIGWPGDPTPEGGEAGFSVGDAGTAISAARAGLGRANVPFMLAEGPLSSGRIVALGEPQVSRR
GYWLVAPPPQWRQKKVKALVAALSS
>Mature_265_residues
MKRTHLPLNGLRVLDAAARHLSFTRAADELAVTPAAVGQQIRALEDLLGVVLFRRTSKGLELTDEASAGLDAIREGFLRF
EEGVQAMQAGQSSHVYTIACPRDFFAAWLSPRLADFRAGNPQMRFSLVGGDADVDFTEANLDLAVRWAEGPGDLEGVSLG
AATMITVAAPDAAPDSPWIGWPGDPTPEGGEAGFSVGDAGTAISAARAGLGRANVPFMLAEGPLSSGRIVALGEPQVSRR
GYWLVAPPPQWRQKKVKALVAALSS

Specific function: Positive regulator of the expression of the gene (blaB) for beta-lactamase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789173, Length=279, Percent_Identity=31.8996415770609, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786448, Length=269, Percent_Identity=29.7397769516729, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788706, Length=291, Percent_Identity=25.7731958762887, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693193, Length=255, Percent_Identity=25.8823529411765, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786401, Length=178, Percent_Identity=29.2134831460674, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 27955; Mature: 27955

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTHLPLNGLRVLDAAARHLSFTRAADELAVTPAAVGQQIRALEDLLGVVLFRRTSKGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
ELTDEASAGLDAIREGFLRFEEGVQAMQAGQSSHVYTIACPRDFFAAWLSPRLADFRAGN
CCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCHHHHHCCCC
PQMRFSLVGGDADVDFTEANLDLAVRWAEGPGDLEGVSLGAATMITVAAPDAAPDSPWIG
CCEEEEEECCCCCCEEEECCCEEEEEECCCCCCCCCEEECCEEEEEEECCCCCCCCCCCC
WPGDPTPEGGEAGFSVGDAGTAISAARAGLGRANVPFMLAEGPLSSGRIVALGEPQVSRR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCCCCCC
GYWLVAPPPQWRQKKVKALVAALSS
CEEEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRTHLPLNGLRVLDAAARHLSFTRAADELAVTPAAVGQQIRALEDLLGVVLFRRTSKGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
ELTDEASAGLDAIREGFLRFEEGVQAMQAGQSSHVYTIACPRDFFAAWLSPRLADFRAGN
CCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCHHHHHCCCC
PQMRFSLVGGDADVDFTEANLDLAVRWAEGPGDLEGVSLGAATMITVAAPDAAPDSPWIG
CCEEEEEECCCCCCEEEECCCEEEEEECCCCCCCCCEEECCEEEEEEECCCCCCCCCCCC
WPGDPTPEGGEAGFSVGDAGTAISAARAGLGRANVPFMLAEGPLSSGRIVALGEPQVSRR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCCCCCC
GYWLVAPPPQWRQKKVKALVAALSS
CEEEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957242 [H]