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The map label for this gene is cynT [H]

Identifier: 87200630

GI number: 87200630

Start: 2831273

End: 2831965

Strand: Reverse

Name: cynT [H]

Synonym: Saro_2617

Alternate gene names: 87200630

Gene position: 2831965-2831273 (Counterclockwise)

Preceding gene: 87200631

Following gene: 87200629

Centisome position: 79.51

GC content: 65.8

Gene sequence:

>693_bases
GTGAACGAACTGATCGGCCGCGTCTTCAGCTTCGAGAAGACCGTATTCCCTGACAGCCGCGAGCTGTTCGGCAAGCTTTC
CACCCAGGGCCAGTCGCCAAAGGCGCTGATGATCTCCTGCGCGGATTCGCGCATCGTGCCTGAACAGATCATGCAGGCCG
AACCCGGCGAACTCTTCGTCTGCCGCAATGCGGGCAACATGGTTCCACCGTTCGCGACCATGAACGGCGGCGTCTCCTCG
ACCGTCGAATATGCGGTCGTGGCGCTCGGCGTGCGCGACATCATCGTCTGCGGCCATTCCGATTGCGGCGCGATGAAGGC
GCTGGCAGCGCCGGAATTGCCGCAAGGCATGCCCAACGTCGTCGCCTGGCTGCGTCACGGCTCAGCTGCGGAGCATGTGG
TGTCGAGCTGTTCTCCGCACCTGCACGGCAACGAGCGCGTGCGCGCGGTCAGCCTCCAGAACATCATCGCCCAGATCGCG
CATCTGCGCACGCATCCCTCCGTCGCCGCAGCCATCGCGCGGGGCGAAATGGCGCTGCACGGCTGGTTCGTCGATATCAG
CGCGGGCATGGTTCTCGGCCTTGATGGCGACACCGGCCAGTTCGTGCCCCTGCGCGAGGATCGTTCGCTTCCTGTCGCCC
TGCCGGCACAGCCGCGCGCCGCGTCCGAACCCCTGGTCGAGGCTGCGGAATGA

Upstream 100 bases:

>100_bases
TGGCGCCCAAGAGAGGCAAAGGCGAAGAGTTACCTTGGTTCACAATCGCGGCATCCCTGTCGCGGTCAACCGCTCCGTTC
TCGGAAAAAGGGTGACTATT

Downstream 100 bases:

>100_bases
GCACCGCCGCCACGGCCGCGCAAGCCGAGGGGAGCGGACCGTTCCGCTTCCTCGCACGCGATTTCACCGCGTCCATCGTC
GTGTTCCTGGTGGCAATGCC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNELIGRVFSFEKTVFPDSRELFGKLSTQGQSPKALMISCADSRIVPEQIMQAEPGELFVCRNAGNMVPPFATMNGGVSS
TVEYAVVALGVRDIIVCGHSDCGAMKALAAPELPQGMPNVVAWLRHGSAAEHVVSSCSPHLHGNERVRAVSLQNIIAQIA
HLRTHPSVAAAIARGEMALHGWFVDISAGMVLGLDGDTGQFVPLREDRSLPVALPAQPRAASEPLVEAAE

Sequences:

>Translated_230_residues
MNELIGRVFSFEKTVFPDSRELFGKLSTQGQSPKALMISCADSRIVPEQIMQAEPGELFVCRNAGNMVPPFATMNGGVSS
TVEYAVVALGVRDIIVCGHSDCGAMKALAAPELPQGMPNVVAWLRHGSAAEHVVSSCSPHLHGNERVRAVSLQNIIAQIA
HLRTHPSVAAAIARGEMALHGWFVDISAGMVLGLDGDTGQFVPLREDRSLPVALPAQPRAASEPLVEAAE
>Mature_230_residues
MNELIGRVFSFEKTVFPDSRELFGKLSTQGQSPKALMISCADSRIVPEQIMQAEPGELFVCRNAGNMVPPFATMNGGVSS
TVEYAVVALGVRDIIVCGHSDCGAMKALAAPELPQGMPNVVAWLRHGSAAEHVVSSCSPHLHGNERVRAVSLQNIIAQIA
HLRTHPSVAAAIARGEMALHGWFVDISAGMVLGLDGDTGQFVPLREDRSLPVALPAQPRAASEPLVEAAE

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=225, Percent_Identity=48, Blast_Score=208, Evalue=2e-55,
Organism=Escherichia coli, GI1786318, Length=197, Percent_Identity=33.502538071066, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25147564, Length=245, Percent_Identity=27.7551020408163, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI115532990, Length=247, Percent_Identity=25.5060728744939, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324292, Length=183, Percent_Identity=28.4153005464481, Blast_Score=86, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24645213, Length=210, Percent_Identity=25.2380952380952, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24425; Mature: 24425

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELIGRVFSFEKTVFPDSRELFGKLSTQGQSPKALMISCADSRIVPEQIMQAEPGELFV
CHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCCCCCEEE
CRNAGNMVPPFATMNGGVSSTVEYAVVALGVRDIIVCGHSDCGAMKALAAPELPQGMPNV
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHEEEEECCCCCCHHHHHCCCCCCCCCHHH
VAWLRHGSAAEHVVSSCSPHLHGNERVRAVSLQNIIAQIAHLRTHPSVAAAIARGEMALH
HHHHHCCCHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEE
GWFVDISAGMVLGLDGDTGQFVPLREDRSLPVALPAQPRAASEPLVEAAE
EEEEEECCCEEEEECCCCCCEEEECCCCCCCEECCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MNELIGRVFSFEKTVFPDSRELFGKLSTQGQSPKALMISCADSRIVPEQIMQAEPGELFV
CHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCCCCCEEE
CRNAGNMVPPFATMNGGVSSTVEYAVVALGVRDIIVCGHSDCGAMKALAAPELPQGMPNV
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHEEEEECCCCCCHHHHHCCCCCCCCCHHH
VAWLRHGSAAEHVVSSCSPHLHGNERVRAVSLQNIIAQIAHLRTHPSVAAAIARGEMALH
HHHHHCCCHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEE
GWFVDISAGMVLGLDGDTGQFVPLREDRSLPVALPAQPRAASEPLVEAAE
EEEEEECCCEEEEECCCCCCEEEECCCCCCCEECCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]