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The map label for this gene is infC

Identifier: 87200551

GI number: 87200551

Start: 2740284

End: 2740805

Strand: Direct

Name: infC

Synonym: Saro_2538

Alternate gene names: 87200551

Gene position: 2740284-2740805 (Clockwise)

Preceding gene: 87200550

Following gene: 87200552

Centisome position: 76.94

GC content: 58.81

Gene sequence:

>522_bases
ATGATGGCGCCCCCCGTAAAGAGCGGGCCTCGCTACAACCAGATGATCAACGTGCCCAAGGTGCGCGTGATCGACGAGAA
CGGCGAGAACCTGGGTGTTATGTACACCCGCGAAGCGATCGAGCAGGCGGCCGATGTCGGACTCGACCTCGTTGAAGTTT
CGCCCAACGCGGACCCGCCGGTCTGCAAGTTCCTCGATGTCGGCAAATTCCGCTACGAAGCGCAGAAGAAGGCCAACCTC
GCCCGCAAGAGCCAGAAGACGCAGGAGATCAAGGAGATCAAGATGCGTCCGAACATCGATGACCACGACTACGAAACCAA
GATGCGTAATGTCGTGAAGTTCATCGGTGAAGGCGACAAGGTGAAGATCACCCTGCGTTTCCGTGGCCGCGAACTTTCGC
ACCAGCAGCTGGGCATGAACCTGCTGCGCAAGGTGCAGGACGATGTGGCGGAAATCGCCAAGGTCGAAGCTTTCCCCCGC
ATGGAAGGTCGCCAGATGCTGATGGTCCTCGCGCCCAAGTAA

Upstream 100 bases:

>100_bases
ATTGCGGACTTTATCTCGGCGCGCATTGTGATAAGAGCGCGCGCATCGTATATTTGGGCAAACTGCAGGAGAAAGCACTA
TAGCTCCCCCACCGCGGCGC

Downstream 100 bases:

>100_bases
GCGCGAAGCCGATCGCTGACGGAAGAAAAGGGCGCGCCGCCGGGTGCGCCCTTTTTCGTTGCAGCAGGTGCTTTCCTGCC
CCGCGCTGCGGGATTTTACG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MMAPPVKSGPRYNQMINVPKVRVIDENGENLGVMYTREAIEQAADVGLDLVEVSPNADPPVCKFLDVGKFRYEAQKKANL
ARKSQKTQEIKEIKMRPNIDDHDYETKMRNVVKFIGEGDKVKITLRFRGRELSHQQLGMNLLRKVQDDVAEIAKVEAFPR
MEGRQMLMVLAPK

Sequences:

>Translated_173_residues
MMAPPVKSGPRYNQMINVPKVRVIDENGENLGVMYTREAIEQAADVGLDLVEVSPNADPPVCKFLDVGKFRYEAQKKANL
ARKSQKTQEIKEIKMRPNIDDHDYETKMRNVVKFIGEGDKVKITLRFRGRELSHQQLGMNLLRKVQDDVAEIAKVEAFPR
MEGRQMLMVLAPK
>Mature_173_residues
MMAPPVKSGPRYNQMINVPKVRVIDENGENLGVMYTREAIEQAADVGLDLVEVSPNADPPVCKFLDVGKFRYEAQKKANL
ARKSQKTQEIKEIKMRPNIDDHDYETKMRNVVKFIGEGDKVKITLRFRGRELSHQQLGMNLLRKVQDDVAEIAKVEAFPR
MEGRQMLMVLAPK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=54.2682926829268, Blast_Score=181, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19768; Mature: 19768

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAPPVKSGPRYNQMINVPKVRVIDENGENLGVMYTREAIEQAADVGLDLVEVSPNADPP
CCCCCCCCCCCCCCEECCCEEEEECCCCCEEEEEEEHHHHHHHHHCCCEEEEECCCCCCC
VCKFLDVGKFRYEAQKKANLARKSQKTQEIKEIKMRPNIDDHDYETKMRNVVKFIGEGDK
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCE
VKITLRFRGRELSHQQLGMNLLRKVQDDVAEIAKVEAFPRMEGRQMLMVLAPK
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
>Mature Secondary Structure
MMAPPVKSGPRYNQMINVPKVRVIDENGENLGVMYTREAIEQAADVGLDLVEVSPNADPP
CCCCCCCCCCCCCCEECCCEEEEECCCCCEEEEEEEHHHHHHHHHCCCEEEEECCCCCCC
VCKFLDVGKFRYEAQKKANLARKSQKTQEIKEIKMRPNIDDHDYETKMRNVVKFIGEGDK
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCE
VKITLRFRGRELSHQQLGMNLLRKVQDDVAEIAKVEAFPRMEGRQMLMVLAPK
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA