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The map label for this gene is tdk

Identifier: 87200500

GI number: 87200500

Start: 2688361

End: 2688939

Strand: Reverse

Name: tdk

Synonym: Saro_2487

Alternate gene names: 87200500

Gene position: 2688939-2688361 (Counterclockwise)

Preceding gene: 87200501

Following gene: 87200499

Centisome position: 75.5

GC content: 65.8

Gene sequence:

>579_bases
GTGGCCAAGCTCTATTTCTACTATGCCAGCATGAACGCCGGCAAATCGACCAACCTGCTCCAGGCGGATTTCAACTACCG
GGAGCGTGGCATGGCGACGATGCTGTGGACCGCCGCGCTGGACGACAGGGGCGGGGAGCGCGCCATCGAAAGCCGCATCG
GGCTGGGCGCGGATGCCCATCGTTTCGATGCCGGGACCGACCTGTGGCAGCGGATTTCGGCGGCGCACGCGGTCCAGCCC
TTGTCCTGCGTGCTGGTCGACGAGGCGCAGTTTCTGCGCCGTGACCAGGTCTGGCAACTGGCGCGAGTGGCTGATGCCGC
AGGAATCCCCGTCCTTTGCTATGGCTTGCGGACCGATTTCCAGGGCGAGCTGTTCGAAGGCTCCGCCGCGCTGCTCGGAA
TTGCCGACTCGCTGATCGAACTCAAGGCCGTCTGCCATTGCGGTCGCAAGGCGACGATGAACCTGCGCGTCGACGATAGC
GGCGCCGCCGTGCGCGCCGGGCGGCAGACCGAGATCGGCGGGAACGACCGCTATGTGGCGCTTTGCCGCCGGCATTTCAG
CGAGGCGATGGGACAATGA

Upstream 100 bases:

>100_bases
AGAGCTTCGACGTCGCCAGCAAGATCGAGACGCTGCTCGCCGATCCGAAGGTCCAGCGCGACCTCAGGGACCAAGAGTCC
GACGGCTGAGGGCGCGCCGG

Downstream 100 bases:

>100_bases
CCGACGAAGCCCTCCATGTGCCTCTGGCCGACGGCGCGCTGCGGCTCGAGATACTGCGCGAAGAGCACCGTGAGGGCCTG
CGCGCGGCTTGCGCCGAGGA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MAKLYFYYASMNAGKSTNLLQADFNYRERGMATMLWTAALDDRGGERAIESRIGLGADAHRFDAGTDLWQRISAAHAVQP
LSCVLVDEAQFLRRDQVWQLARVADAAGIPVLCYGLRTDFQGELFEGSAALLGIADSLIELKAVCHCGRKATMNLRVDDS
GAAVRAGRQTEIGGNDRYVALCRRHFSEAMGQ

Sequences:

>Translated_192_residues
MAKLYFYYASMNAGKSTNLLQADFNYRERGMATMLWTAALDDRGGERAIESRIGLGADAHRFDAGTDLWQRISAAHAVQP
LSCVLVDEAQFLRRDQVWQLARVADAAGIPVLCYGLRTDFQGELFEGSAALLGIADSLIELKAVCHCGRKATMNLRVDDS
GAAVRAGRQTEIGGNDRYVALCRRHFSEAMGQ
>Mature_191_residues
AKLYFYYASMNAGKSTNLLQADFNYRERGMATMLWTAALDDRGGERAIESRIGLGADAHRFDAGTDLWQRISAAHAVQPL
SCVLVDEAQFLRRDQVWQLARVADAAGIPVLCYGLRTDFQGELFEGSAALLGIADSLIELKAVCHCGRKATMNLRVDDSG
AAVRAGRQTEIGGNDRYVALCRRHFSEAMGQ

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family

Homologues:

Organism=Escherichia coli, GI1787490, Length=190, Percent_Identity=56.3157894736842, Blast_Score=233, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KITH_NOVAD (Q2G5F0)

Other databases:

- EMBL:   CP000248
- RefSeq:   YP_497757.1
- ProteinModelPortal:   Q2G5F0
- SMR:   Q2G5F0
- STRING:   Q2G5F0
- GeneID:   3916807
- GenomeReviews:   CP000248_GR
- KEGG:   nar:Saro_2487
- NMPDR:   fig|48935.1.peg.1940
- eggNOG:   COG1435
- HOGENOM:   HBG522108
- OMA:   FRYGAMN
- PhylomeDB:   Q2G5F0
- ProtClustDB:   PRK04296
- BioCyc:   NARO279238:SARO_2487-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00124
- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634
- PANTHER:   PTHR11441
- PIRSF:   PIRSF035805

Pfam domain/function: PF00265 TK

EC number: =2.7.1.21

Molecular weight: Translated: 21079; Mature: 20948

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: ACT_SITE 88-88

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLYFYYASMNAGKSTNLLQADFNYRERGMATMLWTAALDDRGGERAIESRIGLGADAH
CCEEEEEEEECCCCCCCCEEEECCCHHHCCHHHHHEEHHHCCCCCHHHHHHHHCCCCCCH
RFDAGTDLWQRISAAHAVQPLSCVLVDEAQFLRRDQVWQLARVADAAGIPVLCYGLRTDF
HCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
QGELFEGSAALLGIADSLIELKAVCHCGRKATMNLRVDDSGAAVRAGRQTEIGGNDRYVA
CCCEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCCCHHHH
LCRRHFSEAMGQ
HHHHHHHHHHCC
>Mature Secondary Structure 
AKLYFYYASMNAGKSTNLLQADFNYRERGMATMLWTAALDDRGGERAIESRIGLGADAH
CEEEEEEEECCCCCCCCEEEECCCHHHCCHHHHHEEHHHCCCCCHHHHHHHHCCCCCCH
RFDAGTDLWQRISAAHAVQPLSCVLVDEAQFLRRDQVWQLARVADAAGIPVLCYGLRTDF
HCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
QGELFEGSAALLGIADSLIELKAVCHCGRKATMNLRVDDSGAAVRAGRQTEIGGNDRYVA
CCCEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCCCHHHH
LCRRHFSEAMGQ
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA