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The map label for this gene is atsA [H]

Identifier: 87200483

GI number: 87200483

Start: 2667360

End: 2669720

Strand: Direct

Name: atsA [H]

Synonym: Saro_2470

Alternate gene names: 87200483

Gene position: 2667360-2669720 (Clockwise)

Preceding gene: 87200482

Following gene: 87200484

Centisome position: 74.89

GC content: 63.41

Gene sequence:

>2361_bases
ATGCGCGCAATCCGTTCCGCCCTTCGTTTGTCCGCCAGAAAACGCCGGCTCTGCGGAGGTTCCGCCATCGCCGCCTTACT
TGCGCCAACCTTTGTCCTTGCAGAAACCGCCCCTGCCGATCCGCTGGCCGGCAAGGTCGGGCGCACCGTGCAGGTAACAC
ATGCTCCGGCATGGCCTGCCCAACCGCAGGCCCCCAAGGGCGCGCCCAACGTACTGGTCATCCTTACCGACGACGTGGGC
TTTGGCGTGACCAGCGCGTTTGGTGGGCCGGTGCCGACTGCCACTTTCGACGCGCTTGCCCAGACGGGCCTCCGCTACAA
CCGTTTCAACACCACCGCGCTGTGCTCGCCCACGCGCGCCTCGCTCCTGACGGGCCGCCTGCCGCAAAATGTGGACATGG
GCAACGTCACCAACCTGCCGACCGGGTTTGACGGCTACACCACCGTTATCCCGCAGTCCGCAGCCACCGTCGCCGAAGTG
CTGAAGGAAAACGGCTTCAACACCGCGATGTTCGGCAAGAGCCACCTGACGCCCGAATGGCAGACGAGCGCGGCGGGCCC
CTTCGACCAGTGGCCCACGGGCCTGGGGTTCGAATACTTCTACGGCTTCCTTTCGGCAGACACCTCGATGTGGCAGCCGA
GCATTGTCGAGAACACCCTTCCGGTCGAGCCACCTCACGACGATCCAAACTACTTCTTCGAGAAGGACATGGCGGATCAC
GCGATCAAGTGGATGCGCACGCAGCAAGCCGCCGCGCCGGACAAGCCGTTCTTCATGTACTACGCTCCCGGCATTGCCCA
CACTCCGCACCATGCGCCCAAGGAGTGGCTGGAGAAGTTCCGGGGCAAGTTCGATCAGGGCTGGGACAAGCTGCGCGAGG
AGACTTTCGCTCGGCAGAAGCGCATGGGCATCATCCCCGCGAACTCCCGGCTTTCGCCTCGCCCGGCTACGTTGCCCGCC
TGGGATTCATTGAATGCCGACCAGAAGAAGCTCTATTCGCGCCTGATGGAGGCCTACGCAGCGAGCGTCTCGTATTCGGA
TCATCAGACTGGTCGCCTGATCGAAGCGATCCGCGAGACCGGCGAACTGGACAACACGCTGATCATCTACATCCAGGGCG
ACAATGGCAGCAGCGCAGAGGGCGGGCCGGAAGGACTGCTCTACGAACAGTCAACGATCACCGGCCGCAAGGAAACCATG
GCCGAGAAGCTGTCGCACATTGACGATATCGGCGGGCCGAAGCTGTACAACCATTTCCCCGCAGCATGGGCCTGGGCAAC
CAACTCGCCCTTCCCCTGGTGGAAGCAGGTCGCTTCGCAGGCAGGCGGCGTGCGCAACGGCATGGTCGTTTCCTGGCCCA
AGCGCATCACCGAGAGGGGCGTGATCCGCTCGCAATATGCGCACGTCAGCGACATTGCGCCGACCGTGCTCGATGCGGTC
GGGATCAAGTCTCCCGACTTGATCAAGGGCATCAGGCAGAAGCCGGTCGACGGAATCAGCCTAGCCTACACCTTCCAGCA
GGGTTCTGCCCCGTCGGCCAGGCGCATGCAGATCTACGAGATGATGGAGAACTTCGGCATCTACAAGGACGGCTGGATGG
CCGGCACGCTTCCCAAGCGCGCCGCCTGGGAAGCCGGCGCGGCGGGCGACCGCAAGCTCAGCGTCGGGCCCGACGAGCGC
GAATGGTCTCTGTTCAACCTCGATGCCGACTTCACCACGGCCAAGGATCTCGCGAAGCAGAACCCCGCCAAGCTCAAGGA
AATGCAAGATCTGTTCTGGGCGGAAGCCGCAAGAAACAACATTCTGCCGATCCACGACTATAGCCAGGGAACCGAAGGAC
GGCCTTCGCTTGGCGCCTATCGCTCCAGCTTCACCTACCGCCCGGGTACAGCCACGATCGCGGAGGACGCAGCGCCGCAT
ACCATTGGCAAAAGTTTCCGCATCGACGCTGACGTGACTGCAGGCAGCAGCACGAACGGCGTGATGATCGCGCAGGGTGG
TCGCTTCGGCGGCTACAGCTTCTACCTCAAGGACGGGCGTCCGACCTTCCATTACAACGCCGTAGGCGCGGACGCCTTCA
CCGTCGCCGCAGGGAGTGCCCTTGCCGAGGGCAAGCACACGCTTTCCGCAGAGTTCACCGCCGACAAGACCGTGCCGGGA
ACGCCTGGAACGCTGACGCTATATGTCGACGGCAAGGCGGTAGGTTCCAGCAGGCTGGGCCGCACGGTGGCCGGGTGGAT
GTCGCACACCGAAGGCCTCGACGTCGGCCTGGACCGGATAAGCGCGGTCAGTCCCGACTACAGCGTGCAGGATAGTGCCT
TTACCGGCGAGATCGACGAAGTGCGGGTGTCGATCAAATGA

Upstream 100 bases:

>100_bases
CTTCAAGTACTGAGATCCTCCCTTGCCCGGTCGCGCCCTCTTCTTCGGACGGCGGTGCGACCGGGGCTTTTTCAAGATTT
CCGACAAGAGGTTCACCGCG

Downstream 100 bases:

>100_bases
ACCCGAAGCGTGCAAAACGGAGGCGCAGCGCGGTAGCACCACTTGCCTTGTTGCTCGCGATGTCGCTTCCGGTCGTCTCT
TCAGGAGCGGAAATTGCCCG

Product: sulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 786; Mature: 786

Protein sequence:

>786_residues
MRAIRSALRLSARKRRLCGGSAIAALLAPTFVLAETAPADPLAGKVGRTVQVTHAPAWPAQPQAPKGAPNVLVILTDDVG
FGVTSAFGGPVPTATFDALAQTGLRYNRFNTTALCSPTRASLLTGRLPQNVDMGNVTNLPTGFDGYTTVIPQSAATVAEV
LKENGFNTAMFGKSHLTPEWQTSAAGPFDQWPTGLGFEYFYGFLSADTSMWQPSIVENTLPVEPPHDDPNYFFEKDMADH
AIKWMRTQQAAAPDKPFFMYYAPGIAHTPHHAPKEWLEKFRGKFDQGWDKLREETFARQKRMGIIPANSRLSPRPATLPA
WDSLNADQKKLYSRLMEAYAASVSYSDHQTGRLIEAIRETGELDNTLIIYIQGDNGSSAEGGPEGLLYEQSTITGRKETM
AEKLSHIDDIGGPKLYNHFPAAWAWATNSPFPWWKQVASQAGGVRNGMVVSWPKRITERGVIRSQYAHVSDIAPTVLDAV
GIKSPDLIKGIRQKPVDGISLAYTFQQGSAPSARRMQIYEMMENFGIYKDGWMAGTLPKRAAWEAGAAGDRKLSVGPDER
EWSLFNLDADFTTAKDLAKQNPAKLKEMQDLFWAEAARNNILPIHDYSQGTEGRPSLGAYRSSFTYRPGTATIAEDAAPH
TIGKSFRIDADVTAGSSTNGVMIAQGGRFGGYSFYLKDGRPTFHYNAVGADAFTVAAGSALAEGKHTLSAEFTADKTVPG
TPGTLTLYVDGKAVGSSRLGRTVAGWMSHTEGLDVGLDRISAVSPDYSVQDSAFTGEIDEVRVSIK

Sequences:

>Translated_786_residues
MRAIRSALRLSARKRRLCGGSAIAALLAPTFVLAETAPADPLAGKVGRTVQVTHAPAWPAQPQAPKGAPNVLVILTDDVG
FGVTSAFGGPVPTATFDALAQTGLRYNRFNTTALCSPTRASLLTGRLPQNVDMGNVTNLPTGFDGYTTVIPQSAATVAEV
LKENGFNTAMFGKSHLTPEWQTSAAGPFDQWPTGLGFEYFYGFLSADTSMWQPSIVENTLPVEPPHDDPNYFFEKDMADH
AIKWMRTQQAAAPDKPFFMYYAPGIAHTPHHAPKEWLEKFRGKFDQGWDKLREETFARQKRMGIIPANSRLSPRPATLPA
WDSLNADQKKLYSRLMEAYAASVSYSDHQTGRLIEAIRETGELDNTLIIYIQGDNGSSAEGGPEGLLYEQSTITGRKETM
AEKLSHIDDIGGPKLYNHFPAAWAWATNSPFPWWKQVASQAGGVRNGMVVSWPKRITERGVIRSQYAHVSDIAPTVLDAV
GIKSPDLIKGIRQKPVDGISLAYTFQQGSAPSARRMQIYEMMENFGIYKDGWMAGTLPKRAAWEAGAAGDRKLSVGPDER
EWSLFNLDADFTTAKDLAKQNPAKLKEMQDLFWAEAARNNILPIHDYSQGTEGRPSLGAYRSSFTYRPGTATIAEDAAPH
TIGKSFRIDADVTAGSSTNGVMIAQGGRFGGYSFYLKDGRPTFHYNAVGADAFTVAAGSALAEGKHTLSAEFTADKTVPG
TPGTLTLYVDGKAVGSSRLGRTVAGWMSHTEGLDVGLDRISAVSPDYSVQDSAFTGEIDEVRVSIK
>Mature_786_residues
MRAIRSALRLSARKRRLCGGSAIAALLAPTFVLAETAPADPLAGKVGRTVQVTHAPAWPAQPQAPKGAPNVLVILTDDVG
FGVTSAFGGPVPTATFDALAQTGLRYNRFNTTALCSPTRASLLTGRLPQNVDMGNVTNLPTGFDGYTTVIPQSAATVAEV
LKENGFNTAMFGKSHLTPEWQTSAAGPFDQWPTGLGFEYFYGFLSADTSMWQPSIVENTLPVEPPHDDPNYFFEKDMADH
AIKWMRTQQAAAPDKPFFMYYAPGIAHTPHHAPKEWLEKFRGKFDQGWDKLREETFARQKRMGIIPANSRLSPRPATLPA
WDSLNADQKKLYSRLMEAYAASVSYSDHQTGRLIEAIRETGELDNTLIIYIQGDNGSSAEGGPEGLLYEQSTITGRKETM
AEKLSHIDDIGGPKLYNHFPAAWAWATNSPFPWWKQVASQAGGVRNGMVVSWPKRITERGVIRSQYAHVSDIAPTVLDAV
GIKSPDLIKGIRQKPVDGISLAYTFQQGSAPSARRMQIYEMMENFGIYKDGWMAGTLPKRAAWEAGAAGDRKLSVGPDER
EWSLFNLDADFTTAKDLAKQNPAKLKEMQDLFWAEAARNNILPIHDYSQGTEGRPSLGAYRSSFTYRPGTATIAEDAAPH
TIGKSFRIDADVTAGSSTNGVMIAQGGRFGGYSFYLKDGRPTFHYNAVGADAFTVAAGSALAEGKHTLSAEFTADKTVPG
TPGTLTLYVDGKAVGSSRLGRTVAGWMSHTEGLDVGLDRISAVSPDYSVQDSAFTGEIDEVRVSIK

Specific function: Plays an important role in the mineralization of sulfates [H]

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI109389362, Length=366, Percent_Identity=23.7704918032787, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI59797060, Length=366, Percent_Identity=23.224043715847, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI146229331, Length=353, Percent_Identity=28.8951841359773, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI146229329, Length=353, Percent_Identity=28.8951841359773, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI6005990, Length=353, Percent_Identity=28.8951841359773, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI146229324, Length=353, Percent_Identity=28.8951841359773, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4503899, Length=459, Percent_Identity=23.5294117647059, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI157266309, Length=213, Percent_Identity=29.5774647887324, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI58743319, Length=140, Percent_Identity=35, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI53831991, Length=150, Percent_Identity=32, Blast_Score=74, Evalue=8e-13,
Organism=Homo sapiens, GI45430057, Length=235, Percent_Identity=28.936170212766, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI31742482, Length=160, Percent_Identity=33.75, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI71852584, Length=167, Percent_Identity=30.5389221556886, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI71852586, Length=167, Percent_Identity=30.5389221556886, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1790112, Length=316, Percent_Identity=25.3164556962025, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1790233, Length=354, Percent_Identity=25.7062146892655, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559078, Length=245, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281366397, Length=441, Percent_Identity=23.3560090702948, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281366395, Length=441, Percent_Identity=23.3560090702948, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24666163, Length=441, Percent_Identity=23.3560090702948, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24666175, Length=478, Percent_Identity=23.0125523012552, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363223, Length=512, Percent_Identity=22.65625, Blast_Score=90, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24666109, Length=455, Percent_Identity=24.6153846153846, Blast_Score=85, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 85425; Mature: 85425

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIRSALRLSARKRRLCGGSAIAALLAPTFVLAETAPADPLAGKVGRTVQVTHAPAWPA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCCCCHHCCCCEEEEEECCCCCC
QPQAPKGAPNVLVILTDDVGFGVTSAFGGPVPTATFDALAQTGLRYNRFNTTALCSPTRA
CCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHCCCEECCCCCEEECCCHHH
SLLTGRLPQNVDMGNVTNLPTGFDGYTTVIPQSAATVAEVLKENGFNTAMFGKSHLTPEW
HHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCEEECCCCCCCCCC
QTSAAGPFDQWPTGLGFEYFYGFLSADTSMWQPSIVENTLPVEPPHDDPNYFFEKDMADH
CCCCCCCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHH
AIKWMRTQQAAAPDKPFFMYYAPGIAHTPHHAPKEWLEKFRGKFDQGWDKLREETFARQK
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RMGIIPANSRLSPRPATLPAWDSLNADQKKLYSRLMEAYAASVSYSDHQTGRLIEAIRET
HCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GELDNTLIIYIQGDNGSSAEGGPEGLLYEQSTITGRKETMAEKLSHIDDIGGPKLYNHFP
CCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHCCC
AAWAWATNSPFPWWKQVASQAGGVRNGMVVSWPKRITERGVIRSQYAHVSDIAPTVLDAV
CEEEECCCCCCHHHHHHHHHCCCCCCCEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GIKSPDLIKGIRQKPVDGISLAYTFQQGSAPSARRMQIYEMMENFGIYKDGWMAGTLPKR
CCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCH
AAWEAGAAGDRKLSVGPDEREWSLFNLDADFTTAKDLAKQNPAKLKEMQDLFWAEAARNN
HHCCCCCCCCCEECCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
ILPIHDYSQGTEGRPSLGAYRSSFTYRPGTATIAEDAAPHTIGKSFRIDADVTAGSSTNG
CEEECCCCCCCCCCCCHHHHHCCCEECCCCCCHHCCCCCCCCCCCEEEECCEECCCCCCC
VMIAQGGRFGGYSFYLKDGRPTFHYNAVGADAFTVAAGSALAEGKHTLSAEFTADKTVPG
EEEECCCCCCCEEEEEECCCCEEEEECCCCCHHHHHCCCHHHCCCCEEEEEECCCCCCCC
TPGTLTLYVDGKAVGSSRLGRTVAGWMSHTEGLDVGLDRISAVSPDYSVQDSAFTGEIDE
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHH
VRVSIK
EEEEEC
>Mature Secondary Structure
MRAIRSALRLSARKRRLCGGSAIAALLAPTFVLAETAPADPLAGKVGRTVQVTHAPAWPA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCCCCHHCCCCEEEEEECCCCCC
QPQAPKGAPNVLVILTDDVGFGVTSAFGGPVPTATFDALAQTGLRYNRFNTTALCSPTRA
CCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCHHHHHHHHHCCCEECCCCCEEECCCHHH
SLLTGRLPQNVDMGNVTNLPTGFDGYTTVIPQSAATVAEVLKENGFNTAMFGKSHLTPEW
HHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCEEECCCCCCCCCC
QTSAAGPFDQWPTGLGFEYFYGFLSADTSMWQPSIVENTLPVEPPHDDPNYFFEKDMADH
CCCCCCCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHH
AIKWMRTQQAAAPDKPFFMYYAPGIAHTPHHAPKEWLEKFRGKFDQGWDKLREETFARQK
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RMGIIPANSRLSPRPATLPAWDSLNADQKKLYSRLMEAYAASVSYSDHQTGRLIEAIRET
HCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GELDNTLIIYIQGDNGSSAEGGPEGLLYEQSTITGRKETMAEKLSHIDDIGGPKLYNHFP
CCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHCCC
AAWAWATNSPFPWWKQVASQAGGVRNGMVVSWPKRITERGVIRSQYAHVSDIAPTVLDAV
CEEEECCCCCCHHHHHHHHHCCCCCCCEEEECHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GIKSPDLIKGIRQKPVDGISLAYTFQQGSAPSARRMQIYEMMENFGIYKDGWMAGTLPKR
CCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCH
AAWEAGAAGDRKLSVGPDEREWSLFNLDADFTTAKDLAKQNPAKLKEMQDLFWAEAARNN
HHCCCCCCCCCEECCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
ILPIHDYSQGTEGRPSLGAYRSSFTYRPGTATIAEDAAPHTIGKSFRIDADVTAGSSTNG
CEEECCCCCCCCCCCCHHHHHCCCEECCCCCCHHCCCCCCCCCCCEEEECCEECCCCCCC
VMIAQGGRFGGYSFYLKDGRPTFHYNAVGADAFTVAAGSALAEGKHTLSAEFTADKTVPG
EEEECCCCCCCEEEEEECCCCEEEEECCCCCHHHHHCCCHHHCCCCEEEEEECCCCCCCC
TPGTLTLYVDGKAVGSSRLGRTVAGWMSHTEGLDVGLDRISAVSPDYSVQDSAFTGEIDE
CCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHH
VRVSIK
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10336424 [H]