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The map label for this gene is lysA [H]

Identifier: 87200351

GI number: 87200351

Start: 2484413

End: 2485639

Strand: Reverse

Name: lysA [H]

Synonym: Saro_2337

Alternate gene names: 87200351

Gene position: 2485639-2484413 (Counterclockwise)

Preceding gene: 87200352

Following gene: 87200350

Centisome position: 69.79

GC content: 65.61

Gene sequence:

>1227_bases
ATGAAACCGCTCGGCCCGATCCCGCCCGGATACGAAACCATCGACGGCGAACTGGCCGTGGATGGACACAAGGTTACCGA
TCTCGTGATGCAGGCCGGCGGAACGCCGCTCTTCGTCTATTCACGCGCGTTGCTGACCCGGCGGGTTCAGGATCTGCGAG
CTGCCATGCCGGAGCGGCTGGCCATACATTATGCCGTAAAAGCAAATCCTTATATTCCATTATTAAGCCACATGCTGGAG
CTGGTTGATGGGTTCGACATCGCCTCTGGCGGCGAACTTGCCATCGTGCGCGACGCCGGGATCGATCCGGCCATGGTCAG
CTTCGCGGGGCCCGGCAAGCGAGACGCCGAACTCGAGGCGGCGATTGCGGCGGCCGTTACGCTCAACCTTGAATCCGAAG
GCGAGGCGACGCGTGCGCTGGCCATTGCCGGGCGGCTGGGGATCGTCCCCCGTCTCGCGATCAGGGTGAACCCCGATTTC
GATCTCAAGGGATCGGGCATGAAAATGGGCGGCGGGGCGAAGCCGTTCGGCATCGATGCGGAGCGCGTGCCTGCTCTCGC
CCGCAAGCTGATTTCCGCCGGGGCGGAGTGGCGGGGCTTCCACATCTTCGCCGGAAGCCAGGCTCTGTCGGCCGACGCGA
TCATTGAAACGCAGGCGCAGACGATCGGGCTGGCCGCGCGGCTGGCCGAGGAGACGGGCGCGCCCTTGCCGAAGTGCAAT
CTCGGCGGCGGCTTCGGCATTCCATATTTCCCGGGTGACGAGCCGGTCGACGTGGTTGCGGTCGGCGCCGCGCTTGGCGA
CCAGTTCGCGGCGCTGCCCGATGTCCTCCGGGACACGGCATTCTGCATTGAACTAGGCCGCTATCTCGTTGGCGAGGCGG
GGATTTACCTGGCGACCGTGATCGACCGCAAGGAAAGTCACGGCGAGGTCTATCTCGTTACCGACGGCGGCCTGCATCAC
CAGCTCGCCGCCTCGGGCAACTTCGGCACCGTGGTGCGCCGCAACTATCCCAGCGCCATCGCCACGCGCTTCGGCGCGGC
GGTGGAGGAGGAGGCGAGCATCGTTGGCTGCCTGTGCACTCCGCTTGACCGGCTGGCCGACAAGGGCGGCTTTCCCCGGA
CAGATACCGGCGATCTGGTGGTAATCTTCTGTGCCGGTGCCTATGGGGCGAGCGCCAGTCCCGCAGCGTTCCTCGGGCAG
GGTCCGGCCCGGGAAATGCTTGTCTGA

Upstream 100 bases:

>100_bases
TGCCGCGCCAGGTGCATTGGCGCCAGGTCATGCCGGTCAGCCCCAATGGCAAGCTCGACCGCGTTGCGCTGGCCGCCGAA
CTGGCGCAGGACGTGCAGGC

Downstream 100 bases:

>100_bases
CAAAGCGATAGTTCCCGACCGTTAACGCTTGGCGCGGCGTCGGTCCCAGTTCGGGACAGCGACGAATGCGCGCTTGGCGC
AGGCCGGCCGACCAATCAAG

Product: Orn/DAP/Arg decarboxylase 2

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKPLGPIPPGYETIDGELAVDGHKVTDLVMQAGGTPLFVYSRALLTRRVQDLRAAMPERLAIHYAVKANPYIPLLSHMLE
LVDGFDIASGGELAIVRDAGIDPAMVSFAGPGKRDAELEAAIAAAVTLNLESEGEATRALAIAGRLGIVPRLAIRVNPDF
DLKGSGMKMGGGAKPFGIDAERVPALARKLISAGAEWRGFHIFAGSQALSADAIIETQAQTIGLAARLAEETGAPLPKCN
LGGGFGIPYFPGDEPVDVVAVGAALGDQFAALPDVLRDTAFCIELGRYLVGEAGIYLATVIDRKESHGEVYLVTDGGLHH
QLAASGNFGTVVRRNYPSAIATRFGAAVEEEASIVGCLCTPLDRLADKGGFPRTDTGDLVVIFCAGAYGASASPAAFLGQ
GPAREMLV

Sequences:

>Translated_408_residues
MKPLGPIPPGYETIDGELAVDGHKVTDLVMQAGGTPLFVYSRALLTRRVQDLRAAMPERLAIHYAVKANPYIPLLSHMLE
LVDGFDIASGGELAIVRDAGIDPAMVSFAGPGKRDAELEAAIAAAVTLNLESEGEATRALAIAGRLGIVPRLAIRVNPDF
DLKGSGMKMGGGAKPFGIDAERVPALARKLISAGAEWRGFHIFAGSQALSADAIIETQAQTIGLAARLAEETGAPLPKCN
LGGGFGIPYFPGDEPVDVVAVGAALGDQFAALPDVLRDTAFCIELGRYLVGEAGIYLATVIDRKESHGEVYLVTDGGLHH
QLAASGNFGTVVRRNYPSAIATRFGAAVEEEASIVGCLCTPLDRLADKGGFPRTDTGDLVVIFCAGAYGASASPAAFLGQ
GPAREMLV
>Mature_408_residues
MKPLGPIPPGYETIDGELAVDGHKVTDLVMQAGGTPLFVYSRALLTRRVQDLRAAMPERLAIHYAVKANPYIPLLSHMLE
LVDGFDIASGGELAIVRDAGIDPAMVSFAGPGKRDAELEAAIAAAVTLNLESEGEATRALAIAGRLGIVPRLAIRVNPDF
DLKGSGMKMGGGAKPFGIDAERVPALARKLISAGAEWRGFHIFAGSQALSADAIIETQAQTIGLAARLAEETGAPLPKCN
LGGGFGIPYFPGDEPVDVVAVGAALGDQFAALPDVLRDTAFCIELGRYLVGEAGIYLATVIDRKESHGEVYLVTDGGLHH
QLAASGNFGTVVRRNYPSAIATRFGAAVEEEASIVGCLCTPLDRLADKGGFPRTDTGDLVVIFCAGAYGASASPAAFLGQ
GPAREMLV

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Escherichia coli, GI1789203, Length=401, Percent_Identity=26.4339152119701, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 42501; Mature: 42501

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLGPIPPGYETIDGELAVDGHKVTDLVMQAGGTPLFVYSRALLTRRVQDLRAAMPERL
CCCCCCCCCCCEECCCEEEECCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCE
AIHYAVKANPYIPLLSHMLELVDGFDIASGGELAIVRDAGIDPAMVSFAGPGKRDAELEA
EEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHEEEECCCCCCCCHHHH
AIAAAVTLNLESEGEATRALAIAGRLGIVPRLAIRVNPDFDLKGSGMKMGGGAKPFGIDA
EEEEEEEEEECCCCCHHHHEEEHHHHCCCEEEEEEECCCCCCCCCCEECCCCCCCCCCCH
ERVPALARKLISAGAEWRGFHIFAGSQALSADAIIETQAQTIGLAARLAEETGAPLPKCN
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHEEHHHHHHHHHHHHHHHHCCCCCCCC
LGGGFGIPYFPGDEPVDVVAVGAALGDQFAALPDVLRDTAFCIELGRYLVGEAGIYLATV
CCCCCCCCCCCCCCCCEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
IDRKESHGEVYLVTDGGLHHQLAASGNFGTVVRRNYPSAIATRFGAAVEEEASIVGCLCT
ECCCCCCCEEEEEECCCCCEEEECCCCCCEEEECCCCHHHHHHHCCHHHHCCCEEEHHHC
PLDRLADKGGFPRTDTGDLVVIFCAGAYGASASPAAFLGQGPAREMLV
CHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHCCCCHHHCCC
>Mature Secondary Structure
MKPLGPIPPGYETIDGELAVDGHKVTDLVMQAGGTPLFVYSRALLTRRVQDLRAAMPERL
CCCCCCCCCCCEECCCEEEECCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCE
AIHYAVKANPYIPLLSHMLELVDGFDIASGGELAIVRDAGIDPAMVSFAGPGKRDAELEA
EEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHEEEECCCCCCCCHHHH
AIAAAVTLNLESEGEATRALAIAGRLGIVPRLAIRVNPDFDLKGSGMKMGGGAKPFGIDA
EEEEEEEEEECCCCCHHHHEEEHHHHCCCEEEEEEECCCCCCCCCCEECCCCCCCCCCCH
ERVPALARKLISAGAEWRGFHIFAGSQALSADAIIETQAQTIGLAARLAEETGAPLPKCN
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHEEHHHHHHHHHHHHHHHHCCCCCCCC
LGGGFGIPYFPGDEPVDVVAVGAALGDQFAALPDVLRDTAFCIELGRYLVGEAGIYLATV
CCCCCCCCCCCCCCCCEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
IDRKESHGEVYLVTDGGLHHQLAASGNFGTVVRRNYPSAIATRFGAAVEEEASIVGCLCT
ECCCCCCCEEEEEECCCCCEEEECCCCCCEEEECCCCHHHHHHHCCHHHHCCCEEEHHHC
PLDRLADKGGFPRTDTGDLVVIFCAGAYGASASPAAFLGQGPAREMLV
CHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]