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The map label for this gene is ubiE [C]

Identifier: 87200327

GI number: 87200327

Start: 2453627

End: 2454385

Strand: Reverse

Name: ubiE [C]

Synonym: Saro_2313

Alternate gene names: 87200327

Gene position: 2454385-2453627 (Counterclockwise)

Preceding gene: 87200328

Following gene: 87200326

Centisome position: 68.91

GC content: 66.4

Gene sequence:

>759_bases
TTGAGCAGGGCTGCGGCCCTCTCCTCTCTTGCGCTGGTGGCGCTGCTCGCCGCCTGCAAGCCGGCGCCGCAGGACGACCG
GCTCGAAACCGCGCGCGGCTTCCCGCGGGCCGACCGTCCCGTGTCCGGGCCCGGCAGCAACGCCTTCTCCACCGAGAGTG
ACCGCGACAATCGTAACGAAGCCAATACCGTGATGGATCTTGCCGGGGTGAAGCCGGGCATGAGCGTGGCCGACATAGGC
GCGGGCGAGGGGTACTATACGGTGCGCCTTGCCGAGCGCGTCGGCAAGGCGGGTCGCGTCCTGGCGCAGGACATCGACGG
CGACGCCCTGCGCCGGCTGGGTTCGCGCGTCGAGAAGGACCGGCTCGACAACGTGTCGATCAAGCCCGGCGCACCTGACG
ATCCGCGCCTGCCCGAACGCAGCTTCGATCGCGTGTTCATGGTCCACATGTACCACGAGGTGAGCGAGCCCTATGCGTTC
CTGTGGAGGCTATGGCCGGCGCTGAAACCGGGCGGCCGGGTGGTCGTTGTAGATGTCGACAGGTCGACCGACCGGCACGG
GATTCCGCCGGCCCTGCTGATCTGCGAGCTGGAAGCGGTGGGCTTTCGCTTGGACGAATTTCACCGTAAGCCGGAAATAG
CAGGGTACTATGCCCAGTTCGTGGCTGCTTCCAGGCGACCCGAGCCGGAGGGTATAAGGCCTTGTCGACTTAAGGCGGCA
AAGGGTGCGAGCGCCGATGGCGCGTTGAAAGGAAATTGA

Upstream 100 bases:

>100_bases
CCAATCCCACCGAAGTGCTCGACGGCGCGCTCGACCCGTTCATGGCGGCGGCGCTTTCGCAGCGCGTGACCGGCGAGAAG
GTGACGGTGGAGGACGACGA

Downstream 100 bases:

>100_bases
TGTCTGCGTTCAAGGGGTTGAAGCCGATTCTCTATGGTGGCCGTGAAGTCTGGCCACTGGTCGAGGGCGGCAAGGGCGTG
GCGGCGACGAACCACATGAG

Product: generic methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: SAM-Dependent Methyltransferase; Methyltransferase UbiE/COQ5 Family; Ubiquinone/Menaquinone Biosynthesis Methyltransferase; Generic Methyltransferase; Methylase

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSRAAALSSLALVALLAACKPAPQDDRLETARGFPRADRPVSGPGSNAFSTESDRDNRNEANTVMDLAGVKPGMSVADIG
AGEGYYTVRLAERVGKAGRVLAQDIDGDALRRLGSRVEKDRLDNVSIKPGAPDDPRLPERSFDRVFMVHMYHEVSEPYAF
LWRLWPALKPGGRVVVVDVDRSTDRHGIPPALLICELEAVGFRLDEFHRKPEIAGYYAQFVAASRRPEPEGIRPCRLKAA
KGASADGALKGN

Sequences:

>Translated_252_residues
MSRAAALSSLALVALLAACKPAPQDDRLETARGFPRADRPVSGPGSNAFSTESDRDNRNEANTVMDLAGVKPGMSVADIG
AGEGYYTVRLAERVGKAGRVLAQDIDGDALRRLGSRVEKDRLDNVSIKPGAPDDPRLPERSFDRVFMVHMYHEVSEPYAF
LWRLWPALKPGGRVVVVDVDRSTDRHGIPPALLICELEAVGFRLDEFHRKPEIAGYYAQFVAASRRPEPEGIRPCRLKAA
KGASADGALKGN
>Mature_251_residues
SRAAALSSLALVALLAACKPAPQDDRLETARGFPRADRPVSGPGSNAFSTESDRDNRNEANTVMDLAGVKPGMSVADIGA
GEGYYTVRLAERVGKAGRVLAQDIDGDALRRLGSRVEKDRLDNVSIKPGAPDDPRLPERSFDRVFMVHMYHEVSEPYAFL
WRLWPALKPGGRVVVVDVDRSTDRHGIPPALLICELEAVGFRLDEFHRKPEIAGYYAQFVAASRRPEPEGIRPCRLKAAK
GASADGALKGN

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27389; Mature: 27258

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAAALSSLALVALLAACKPAPQDDRLETARGFPRADRPVSGPGSNAFSTESDRDNRNE
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
ANTVMDLAGVKPGMSVADIGAGEGYYTVRLAERVGKAGRVLAQDIDGDALRRLGSRVEKD
HHHHHHHHCCCCCCCEEECCCCCCEEEEEEHHHHCHHHHHHHHCCCHHHHHHHHHHHHHH
RLDNVSIKPGAPDDPRLPERSFDRVFMVHMYHEVSEPYAFLWRLWPALKPGGRVVVVDVD
HCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEECC
RSTDRHGIPPALLICELEAVGFRLDEFHRKPEIAGYYAQFVAASRRPEPEGIRPCRLKAA
CCCCCCCCCHHHEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECC
KGASADGALKGN
CCCCCCCCCCCC
>Mature Secondary Structure 
SRAAALSSLALVALLAACKPAPQDDRLETARGFPRADRPVSGPGSNAFSTESDRDNRNE
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
ANTVMDLAGVKPGMSVADIGAGEGYYTVRLAERVGKAGRVLAQDIDGDALRRLGSRVEKD
HHHHHHHHCCCCCCCEEECCCCCCEEEEEEHHHHCHHHHHHHHCCCHHHHHHHHHHHHHH
RLDNVSIKPGAPDDPRLPERSFDRVFMVHMYHEVSEPYAFLWRLWPALKPGGRVVVVDVD
HCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEECC
RSTDRHGIPPALLICELEAVGFRLDEFHRKPEIAGYYAQFVAASRRPEPEGIRPCRLKAA
CCCCCCCCCHHHEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECC
KGASADGALKGN
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA