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The map label for this gene is serB [H]

Identifier: 87200273

GI number: 87200273

Start: 2398070

End: 2398954

Strand: Reverse

Name: serB [H]

Synonym: Saro_2259

Alternate gene names: 87200273

Gene position: 2398954-2398070 (Counterclockwise)

Preceding gene: 87200280

Following gene: 87200271

Centisome position: 67.36

GC content: 64.07

Gene sequence:

>885_bases
GTGATCATCGCGCGCCTGATAGCAGACCCGGAGACGCTTGGTGACAATCTTGCGCTCGCCATGGAAATGATCGAGGCCCG
TGACTGGGAAGTGGCCGGCGCCGGGATGCTGGAATTCTGTTCGGAAGTGCTCGAACTGGAAGTGGTCGAAGGCAATCCCG
TAGGTATCCGCCAGATACTCGACCAGTGCTTCCCGGAAAGCGACCTGCTGCTTTCCAACGGACTGATCGAAGTGCCCCAC
CTGTTCGTGTCGGACATGGATTCGACCATGATCGGCCAGGAGTGCATCGACGAACTGGCTGATTTCGCCGGTCTCAAGGA
ACGCATCGCCGCGATCACCGAGCGTGCGATGCAGGGCGAACTCGATTTCGAGTCCGCGTTGCGCGAGCGCGTGGGACTGC
TGAAGGATCTGCCCGAAGCCGCCATCGCCCAGTGCCTTGACGAGCGCATCCGGCCCATGCCCGGCGCGCGCACGCTCGTG
TCGACCCTAAAGGCGCGCGGTTGCCATACCGTGCTGGTGACGGGCGGCTTTCATTCCTTCGCCGATCCGGTCGCGGACCT
TCTCGGCTTCGACCGGGTGGTGGGCAACCGGCTCGGCCTTCATGAAGGCGTGCTGACGGGCGGCCTGGTGGGCGGCATCG
TCGACAGCTCGATCAAGAAGAAGGTGCTGCTGGAAGAGGCCGAGCGCCTGGGCGAGGGCTCTTTGAGCCTGGCGACCGGC
GATGGAGCCAACGATATCCCCATGATCGAGGCGGCAAGCTTCGGCATCGCCTATCGCGCAAAGCCCAAGGCCCGCGCGGC
GGCGGATGGCTGGATCGACCGGGGCGACCTGACGTCCATTCTCTCGCTGCTGGGCATTGCCCGCGAGGACTGGGTGTTCG
ACTGA

Upstream 100 bases:

>100_bases
GGCCAAATCGCTCTTGCCGCTGGCCGTCGGCCCTGCGATTAGCGCCAACCTTGGCCGTTCGGCCGCTGCCTTCACGTTAT
CGTCCAAAAAGGAATTCCCG

Downstream 100 bases:

>100_bases
TCAGGCGAGCCCAGCGGCGCGGCGAGGGCGACGGGCAAGTACGCGCAAGCCCAGCGCGGCCAGTGCGAGCAGGGTCATGG
GCACCGCTATGGCCCGCGAT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MIIARLIADPETLGDNLALAMEMIEARDWEVAGAGMLEFCSEVLELEVVEGNPVGIRQILDQCFPESDLLLSNGLIEVPH
LFVSDMDSTMIGQECIDELADFAGLKERIAAITERAMQGELDFESALRERVGLLKDLPEAAIAQCLDERIRPMPGARTLV
STLKARGCHTVLVTGGFHSFADPVADLLGFDRVVGNRLGLHEGVLTGGLVGGIVDSSIKKKVLLEEAERLGEGSLSLATG
DGANDIPMIEAASFGIAYRAKPKARAAADGWIDRGDLTSILSLLGIAREDWVFD

Sequences:

>Translated_294_residues
MIIARLIADPETLGDNLALAMEMIEARDWEVAGAGMLEFCSEVLELEVVEGNPVGIRQILDQCFPESDLLLSNGLIEVPH
LFVSDMDSTMIGQECIDELADFAGLKERIAAITERAMQGELDFESALRERVGLLKDLPEAAIAQCLDERIRPMPGARTLV
STLKARGCHTVLVTGGFHSFADPVADLLGFDRVVGNRLGLHEGVLTGGLVGGIVDSSIKKKVLLEEAERLGEGSLSLATG
DGANDIPMIEAASFGIAYRAKPKARAAADGWIDRGDLTSILSLLGIAREDWVFD
>Mature_294_residues
MIIARLIADPETLGDNLALAMEMIEARDWEVAGAGMLEFCSEVLELEVVEGNPVGIRQILDQCFPESDLLLSNGLIEVPH
LFVSDMDSTMIGQECIDELADFAGLKERIAAITERAMQGELDFESALRERVGLLKDLPEAAIAQCLDERIRPMPGARTLV
STLKARGCHTVLVTGGFHSFADPVADLLGFDRVVGNRLGLHEGVLTGGLVGGIVDSSIKKKVLLEEAERLGEGSLSLATG
DGANDIPMIEAASFGIAYRAKPKARAAADGWIDRGDLTSILSLLGIAREDWVFD

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=180, Percent_Identity=32.7777777777778, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790849, Length=210, Percent_Identity=44.2857142857143, Blast_Score=158, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI115534454, Length=169, Percent_Identity=33.1360946745562, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115534456, Length=169, Percent_Identity=33.1360946745562, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115534458, Length=171, Percent_Identity=32.7485380116959, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321647, Length=231, Percent_Identity=37.6623376623377, Blast_Score=143, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24661601, Length=137, Percent_Identity=31.3868613138686, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31586; Mature: 31586

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIARLIADPETLGDNLALAMEMIEARDWEVAGAGMLEFCSEVLELEVVEGNPVGIRQIL
CCHHHHHCCHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHH
DQCFPESDLLLSNGLIEVPHLFVSDMDSTMIGQECIDELADFAGLKERIAAITERAMQGE
HHHCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LDFESALRERVGLLKDLPEAAIAQCLDERIRPMPGARTLVSTLKARGCHTVLVTGGFHSF
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCHHH
ADPVADLLGFDRVVGNRLGLHEGVLTGGLVGGIVDSSIKKKVLLEEAERLGEGSLSLATG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DGANDIPMIEAASFGIAYRAKPKARAAADGWIDRGDLTSILSLLGIAREDWVFD
CCCCCCCCHHHHCCCEEEECCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIIARLIADPETLGDNLALAMEMIEARDWEVAGAGMLEFCSEVLELEVVEGNPVGIRQIL
CCHHHHHCCHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEEECCCCCCHHHHH
DQCFPESDLLLSNGLIEVPHLFVSDMDSTMIGQECIDELADFAGLKERIAAITERAMQGE
HHHCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LDFESALRERVGLLKDLPEAAIAQCLDERIRPMPGARTLVSTLKARGCHTVLVTGGFHSF
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCHHH
ADPVADLLGFDRVVGNRLGLHEGVLTGGLVGGIVDSSIKKKVLLEEAERLGEGSLSLATG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DGANDIPMIEAASFGIAYRAKPKARAAADGWIDRGDLTSILSLLGIAREDWVFD
CCCCCCCCHHHHCCCEEEECCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]