Click here to switch to the map view.

The map label for this gene is ispA [H]

Identifier: 87200267

GI number: 87200267

Start: 2392634

End: 2393545

Strand: Reverse

Name: ispA [H]

Synonym: Saro_2253

Alternate gene names: 87200267

Gene position: 2393545-2392634 (Counterclockwise)

Preceding gene: 87200268

Following gene: 87200266

Centisome position: 67.2

GC content: 67.43

Gene sequence:

>912_bases
ATGTCGGCTGACACGTCGGAAGGACCGGGCCTCCTCAAGCCAGCCCTTGCGGCTATCGCCGAGGACATCGACCGCAGCTT
CGACCTGCTGCTGCCGGTCCCGGGCGACCCGCGCGACCGGCTGGTCGAAGCCATGCGCTATGCGGCCATTGGTGGCGGCA
AGCGGCTGCGCCCGTTGCTGGTCTGCGCGACCGGCGCCCTGCACGGCGTTTCGCGCGAGGCGGCGGTGCGGGTCGGCACG
GCGATCGAGGCCATCCACGTCTATTCGCTGATCCACGACGACCTGCCCTGCATGGACAATGACGGGCTGCGCCATGGCAA
GCCCACCGTCCACGTGGCGTTCGACGATGCAACCGCGGTGCTGGCCGGCGATGCCCTGCACGACTTCGCTTTCGAAGTGT
TGTCCGATCCCGCGACCAGCGGCGACCCTTTCACGCGGATCGAACTGATCCGCACGCTTGCCACCGCGAGCGGCATGAAC
GGCATGTGCGGCGGGCAGATGATGGACATCGTCGCCGAGACTTCCAGTTTCGACCTGCCCACCGTGACCCGGCTCCAGCA
GCTCAAGACGGGCGCATTGCTGGGCGCATCTGTGGAACTGGGCGCGATCCTTGGGAAGGTGCCGCCCGAAGGGCGCACCC
ATCTGCGTGGCTATGCGCGCGACATCGGCCTTGCCTTCCAGATCGCGGATGACCTGCTCGACGCCGAAGGCGACGAAGCC
GCCGCCGGCAAGGCGCTGCGCAAGGACGCCGCGCAGGGCAAGGAGACCTTCCTGTCGCTGCTGGGCGCCGATCGCGCTCG
TGAACAGGCCCGACTGCTGGTGAACCAGGCGGTCGAACATCTTGCAAGCTATGGTCCCGAAGCGGACCTGCTGCGCGAAC
TTGCGCGCTTCATCGTGGAGAGGAACCACTGA

Upstream 100 bases:

>100_bases
ATGCGGCGCAGGCGCGAATCGAAGCGATCGTGGCCGACCGTGACGGCAAGGCCCAAGGCCTTCGTCCGTTCGACGAAACC
GTCGGTTGAGCGATAACGCC

Downstream 100 bases:

>100_bases
TGGCCGAACGTATCGGCGTATACCCCGGAACTTTCGATCCGATCACGCTCGGGCATCTCGACATCATCCGTCGCGGCGCC
AAGCTGGTCGACAAGCTGAT

Product: farnesyl-diphosphate synthase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSADTSEGPGLLKPALAAIAEDIDRSFDLLLPVPGDPRDRLVEAMRYAAIGGGKRLRPLLVCATGALHGVSREAAVRVGT
AIEAIHVYSLIHDDLPCMDNDGLRHGKPTVHVAFDDATAVLAGDALHDFAFEVLSDPATSGDPFTRIELIRTLATASGMN
GMCGGQMMDIVAETSSFDLPTVTRLQQLKTGALLGASVELGAILGKVPPEGRTHLRGYARDIGLAFQIADDLLDAEGDEA
AAGKALRKDAAQGKETFLSLLGADRAREQARLLVNQAVEHLASYGPEADLLRELARFIVERNH

Sequences:

>Translated_303_residues
MSADTSEGPGLLKPALAAIAEDIDRSFDLLLPVPGDPRDRLVEAMRYAAIGGGKRLRPLLVCATGALHGVSREAAVRVGT
AIEAIHVYSLIHDDLPCMDNDGLRHGKPTVHVAFDDATAVLAGDALHDFAFEVLSDPATSGDPFTRIELIRTLATASGMN
GMCGGQMMDIVAETSSFDLPTVTRLQQLKTGALLGASVELGAILGKVPPEGRTHLRGYARDIGLAFQIADDLLDAEGDEA
AAGKALRKDAAQGKETFLSLLGADRAREQARLLVNQAVEHLASYGPEADLLRELARFIVERNH
>Mature_302_residues
SADTSEGPGLLKPALAAIAEDIDRSFDLLLPVPGDPRDRLVEAMRYAAIGGGKRLRPLLVCATGALHGVSREAAVRVGTA
IEAIHVYSLIHDDLPCMDNDGLRHGKPTVHVAFDDATAVLAGDALHDFAFEVLSDPATSGDPFTRIELIRTLATASGMNG
MCGGQMMDIVAETSSFDLPTVTRLQQLKTGALLGASVELGAILGKVPPEGRTHLRGYARDIGLAFQIADDLLDAEGDEAA
AGKALRKDAAQGKETFLSLLGADRAREQARLLVNQAVEHLASYGPEADLLRELARFIVERNH

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=281, Percent_Identity=46.9750889679715, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789578, Length=216, Percent_Identity=31.4814814814815, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 32161; Mature: 32030

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADTSEGPGLLKPALAAIAEDIDRSFDLLLPVPGDPRDRLVEAMRYAAIGGGKRLRPLL
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHH
VCATGALHGVSREAAVRVGTAIEAIHVYSLIHDDLPCMDNDGLRHGKPTVHVAFDDATAV
EEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHH
LAGDALHDFAFEVLSDPATSGDPFTRIELIRTLATASGMNGMCGGQMMDIVAETSSFDLP
HCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCH
TVTRLQQLKTGALLGASVELGAILGKVPPEGRTHLRGYARDIGLAFQIADDLLDAEGDEA
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
AAGKALRKDAAQGKETFLSLLGADRAREQARLLVNQAVEHLASYGPEADLLRELARFIVE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RNH
CCC
>Mature Secondary Structure 
SADTSEGPGLLKPALAAIAEDIDRSFDLLLPVPGDPRDRLVEAMRYAAIGGGKRLRPLL
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHH
VCATGALHGVSREAAVRVGTAIEAIHVYSLIHDDLPCMDNDGLRHGKPTVHVAFDDATAV
EEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHH
LAGDALHDFAFEVLSDPATSGDPFTRIELIRTLATASGMNGMCGGQMMDIVAETSSFDLP
HCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCH
TVTRLQQLKTGALLGASVELGAILGKVPPEGRTHLRGYARDIGLAFQIADDLLDAEGDEA
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
AAGKALRKDAAQGKETFLSLLGADRAREQARLLVNQAVEHLASYGPEADLLRELARFIVE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RNH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]