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The map label for this gene is yqgN [H]

Identifier: 87199988

GI number: 87199988

Start: 2088711

End: 2089298

Strand: Direct

Name: yqgN [H]

Synonym: Saro_1971

Alternate gene names: 87199988

Gene position: 2088711-2089298 (Clockwise)

Preceding gene: 87199987

Following gene: 87199989

Centisome position: 58.65

GC content: 66.16

Gene sequence:

>588_bases
GTGGAAGGCAAGAATGCGCTGCGCAAGGAATTGAGGGCGCGGCGCAATGCCCACGTGGCGGCGCTCGACCCGCGCGTAAG
GGCGCTGATGTTCATGCGCCCGCCCTCCCCGGTGACCGCACTGGTTCCCCAGGATGCAACCGTTGGCGTCTACCTTGCCG
GGCCCGGCGAGGCCCCTGCCACAGCCTATGCCCGTCATTTCCACGAAGCCGGACACAAGATCGCCCTGCCCTGGTTCGCG
GACCGCGATTCGCCGATGCAGTTTCGCGAGTGGTCCTCACCGTGGGTGGACGAATTGCTTGAGCCGGGCCCATGGCAGAG
CATCGCTCAACCGCAGGCGAGTGCTCCTGTCGCAAAGCCCGAGGTGGTCTTCGTCCCCCTTGTCGGATTTGACGCCGAAG
GCGGACGCCTTGGGCAAGGTGGCGGGCACTACGATCGATGGATCGAGGCTCATCCGGCGGCGGTGCGCATCGGGCTTGCC
TGGGATTGCCAGCTGGTCGACCGCCTTCCCCGCGAAACGCATGACCGGGCGCTTCATGCGGTGGTAACGCCGACGCGAAT
CTACGGACCGTGGGAGCAGGACAAGTGA

Upstream 100 bases:

>100_bases
CGGTCCCCACCTGACGTCGAGGCGTCAGAGGATTTTCCGAGCAAACGACCCATGGTGGGCCCGTCACCCTCCCCTTTTGC
ATGAATTTTCGGAGCACCGC

Downstream 100 bases:

>100_bases
AGCAGGACTATCGACCAACCTGGCGCAAGCCCGTCGGCATTCTCGGCCTGGTGTTGGCCCTGGTGGTCTATGCCTTCGGG
ATTGCCGCCCTGTCGGGGAC

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MEGKNALRKELRARRNAHVAALDPRVRALMFMRPPSPVTALVPQDATVGVYLAGPGEAPATAYARHFHEAGHKIALPWFA
DRDSPMQFREWSSPWVDELLEPGPWQSIAQPQASAPVAKPEVVFVPLVGFDAEGGRLGQGGGHYDRWIEAHPAAVRIGLA
WDCQLVDRLPRETHDRALHAVVTPTRIYGPWEQDK

Sequences:

>Translated_195_residues
MEGKNALRKELRARRNAHVAALDPRVRALMFMRPPSPVTALVPQDATVGVYLAGPGEAPATAYARHFHEAGHKIALPWFA
DRDSPMQFREWSSPWVDELLEPGPWQSIAQPQASAPVAKPEVVFVPLVGFDAEGGRLGQGGGHYDRWIEAHPAAVRIGLA
WDCQLVDRLPRETHDRALHAVVTPTRIYGPWEQDK
>Mature_195_residues
MEGKNALRKELRARRNAHVAALDPRVRALMFMRPPSPVTALVPQDATVGVYLAGPGEAPATAYARHFHEAGHKIALPWFA
DRDSPMQFREWSSPWVDELLEPGPWQSIAQPQASAPVAKPEVVFVPLVGFDAEGGRLGQGGGHYDRWIEAHPAAVRIGLA
WDCQLVDRLPRETHDRALHAVVTPTRIYGPWEQDK

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Escherichia coli, GI1789278, Length=152, Percent_Identity=32.8947368421053, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 21643; Mature: 21643

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGKNALRKELRARRNAHVAALDPRVRALMFMRPPSPVTALVPQDATVGVYLAGPGEAPA
CCCHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCEEEECCCCCEEEEEEECCCCCCH
TAYARHFHEAGHKIALPWFADRDSPMQFREWSSPWVDELLEPGPWQSIAQPQASAPVAKP
HHHHHHHHHCCCEEEECEECCCCCCCHHHHCCCHHHHHHCCCCCCHHHCCCCCCCCCCCC
EVVFVPLVGFDAEGGRLGQGGGHYDRWIEAHPAAVRIGLAWDCQLVDRLPRETHDRALHA
CEEEEEEEEECCCCCEECCCCCCHHHHHHCCCCEEEEEEEECHHHHHHCCHHHHHHHEEE
VVTPTRIYGPWEQDK
EECCCEEECCCCCCC
>Mature Secondary Structure
MEGKNALRKELRARRNAHVAALDPRVRALMFMRPPSPVTALVPQDATVGVYLAGPGEAPA
CCCHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCEEEECCCCCEEEEEEECCCCCCH
TAYARHFHEAGHKIALPWFADRDSPMQFREWSSPWVDELLEPGPWQSIAQPQASAPVAKP
HHHHHHHHHCCCEEEECEECCCCCCCHHHHCCCHHHHHHCCCCCCHHHCCCCCCCCCCCC
EVVFVPLVGFDAEGGRLGQGGGHYDRWIEAHPAAVRIGLAWDCQLVDRLPRETHDRALHA
CEEEEEEEEECCCCCEECCCCCCHHHHHHCCCCEEEEEEEECHHHHHHCCHHHHHHHEEE
VVTPTRIYGPWEQDK
EECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]