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The map label for this gene is ykoH [H]

Identifier: 87199617

GI number: 87199617

Start: 1663284

End: 1664690

Strand: Direct

Name: ykoH [H]

Synonym: Saro_1600

Alternate gene names: 87199617

Gene position: 1663284-1664690 (Clockwise)

Preceding gene: 87199616

Following gene: 87199619

Centisome position: 46.7

GC content: 68.73

Gene sequence:

>1407_bases
ATGCTGCGCGGGATGCTGCGCTCGACGACCGTGCGGTTCGCCGCGCTCGTGTTCCTGCTGCAGGTCGTGGCAGCGGCGTT
CATGCTGGGCGGCCTTGGCGCCGTAATGCGGCAGCAGAGCCGCGCGCAGGCCCTCGATACCGTGGAAACCCTGCGCGACG
ACCTGATGGCGACGACGGCACAGGGCGGCGAGCGGCAATTGGTCGAGGCGATCAGGCTGCGGCTGGCGAACGAGGTCGGC
CGGGGTGTCGTGGTGGCGCTGGTGGACCCGTCCGGACGTCTGGTGGAGGGCAATCTGGCTCGCATGCCCGACGACGGTTT
CGCCGTGCACCTGAACAGGGTCGCCAGCGTCGTCAACGTGCGACGGCGCAATCACGCGGCTGACGAGGCAGCTCTCATCG
TAGCTGCGCGCCTGCCCGGCGGCCAACTACTGCTCGCCGGAACGGTGGTGGAAAGCGACAGGCAATTCCTGGCGCTGCTC
GAACGCGCCAGCATTGCGACGCTGGCGTTGTCCCTTCTTCTGGCGGGGCTGGCGTCCTTTCTGGCGACGCGGCAGATCGT
CCAGCGGTTGCGCGGTACGGTCGCGACGCTCGAGGCCGTCGGGGCAGGCGATCTGGCCCGCCGGGTGCCGCCCGACGGGT
CCGGAGACGCGTTTTCGCGGCTGGGCGAGGAGGTCAACCGCGCGCTGGCCCGGGCCGAGGCGCTGAACGGGGAACTGAAA
ATTGCGACCGACGTCCTCGCCCACGATCTCAAGTCACCTTTGACGCGATTGCTGTCGGCGCTGGATCGCGCTTCGGCCCG
CGCCGAGGATGCCGAGGCGCTTGCCGCCGTTGAGCAAGCCGAGGCGGAGGCACGGCGGGTGCTTTCGATCATCGACACGG
CGCTTGGCATCTCGAAGGCCGAGGCGGGGTTCGGCCGCGAGAGTTTCACGCCTGTCGATCTCGGCGCAATGCTCGAGACG
ATCGCCGAAATCTACGCGCCGGTGGTGGAAGAGGAGGGGCGTCGCATGGAAGTGCAGGCACCGCCGGGACTGGTGGTGCC
GATCCATCGCCAGCTCATGGATCAGGCCATCGGCAACCTGCTGGACAACACGATCCGTTATGGCGCCGGGGCGATAAGCC
TTGCTGTGGAGCCGCGCGACGGCGCGATGGCGATTTCGGTTGCTGACGAAGGGCCCGGCATTCCGCAACACCAGCACGAA
GAAGCGCTGCGCAGGTTCGGAAGGCTCGACGAGGCGCGTGGCGGTTGGGGCGCAGGGCTCGGGCTCGCTCTGGTCGAAGC
GGTCGCGCACTTGCACGGAGGGCGGGTCGAACTGGCCGAAAACCGGCAATCGCGGTCCGGCCAGCCGGGTTTGAAGGTGA
CGCTGGTGCTCGGGCAACGCGCTCCGGGCGGCGGCGATAGCGGTTGA

Upstream 100 bases:

>100_bases
TCCACATCAGTCGCCTGCGCAAGAAGATCGACGAGGGCGAGGTCGTCGCCTTGCTTCACACCGTGCGGGGCGCCGGTTAC
CGCATCGGCACAGGTGCGTG

Downstream 100 bases:

>100_bases
TGCACCGCTTCGCCGCCGCCCGCATGGGTTCAGAACGCGAGGCCCAGCAGGAGACCGCCGGCTGCCGCGACGGCCAGTAC
GCGGATGATGTTCCACTTCA

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MLRGMLRSTTVRFAALVFLLQVVAAAFMLGGLGAVMRQQSRAQALDTVETLRDDLMATTAQGGERQLVEAIRLRLANEVG
RGVVVALVDPSGRLVEGNLARMPDDGFAVHLNRVASVVNVRRRNHAADEAALIVAARLPGGQLLLAGTVVESDRQFLALL
ERASIATLALSLLLAGLASFLATRQIVQRLRGTVATLEAVGAGDLARRVPPDGSGDAFSRLGEEVNRALARAEALNGELK
IATDVLAHDLKSPLTRLLSALDRASARAEDAEALAAVEQAEAEARRVLSIIDTALGISKAEAGFGRESFTPVDLGAMLET
IAEIYAPVVEEEGRRMEVQAPPGLVVPIHRQLMDQAIGNLLDNTIRYGAGAISLAVEPRDGAMAISVADEGPGIPQHQHE
EALRRFGRLDEARGGWGAGLGLALVEAVAHLHGGRVELAENRQSRSGQPGLKVTLVLGQRAPGGGDSG

Sequences:

>Translated_468_residues
MLRGMLRSTTVRFAALVFLLQVVAAAFMLGGLGAVMRQQSRAQALDTVETLRDDLMATTAQGGERQLVEAIRLRLANEVG
RGVVVALVDPSGRLVEGNLARMPDDGFAVHLNRVASVVNVRRRNHAADEAALIVAARLPGGQLLLAGTVVESDRQFLALL
ERASIATLALSLLLAGLASFLATRQIVQRLRGTVATLEAVGAGDLARRVPPDGSGDAFSRLGEEVNRALARAEALNGELK
IATDVLAHDLKSPLTRLLSALDRASARAEDAEALAAVEQAEAEARRVLSIIDTALGISKAEAGFGRESFTPVDLGAMLET
IAEIYAPVVEEEGRRMEVQAPPGLVVPIHRQLMDQAIGNLLDNTIRYGAGAISLAVEPRDGAMAISVADEGPGIPQHQHE
EALRRFGRLDEARGGWGAGLGLALVEAVAHLHGGRVELAENRQSRSGQPGLKVTLVLGQRAPGGGDSG
>Mature_468_residues
MLRGMLRSTTVRFAALVFLLQVVAAAFMLGGLGAVMRQQSRAQALDTVETLRDDLMATTAQGGERQLVEAIRLRLANEVG
RGVVVALVDPSGRLVEGNLARMPDDGFAVHLNRVASVVNVRRRNHAADEAALIVAARLPGGQLLLAGTVVESDRQFLALL
ERASIATLALSLLLAGLASFLATRQIVQRLRGTVATLEAVGAGDLARRVPPDGSGDAFSRLGEEVNRALARAEALNGELK
IATDVLAHDLKSPLTRLLSALDRASARAEDAEALAAVEQAEAEARRVLSIIDTALGISKAEAGFGRESFTPVDLGAMLET
IAEIYAPVVEEEGRRMEVQAPPGLVVPIHRQLMDQAIGNLLDNTIRYGAGAISLAVEPRDGAMAISVADEGPGIPQHQHE
EALRRFGRLDEARGGWGAGLGLALVEAVAHLHGGRVELAENRQSRSGQPGLKVTLVLGQRAPGGGDSG

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=26.6129032258064, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787894, Length=284, Percent_Identity=28.8732394366197, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790346, Length=207, Percent_Identity=29.951690821256, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790861, Length=238, Percent_Identity=28.1512605042017, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788279, Length=294, Percent_Identity=23.8095238095238, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49309; Mature: 49309

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRGMLRSTTVRFAALVFLLQVVAAAFMLGGLGAVMRQQSRAQALDTVETLRDDLMATTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QGGERQLVEAIRLRLANEVGRGVVVALVDPSGRLVEGNLARMPDDGFAVHLNRVASVVNV
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCHHCCCCCCHHHHHHHHHHHHHH
RRRNHAADEAALIVAARLPGGQLLLAGTVVESDRQFLALLERASIATLALSLLLAGLASF
HHHCCCCCHHEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATRQIVQRLRGTVATLEAVGAGDLARRVPPDGSGDAFSRLGEEVNRALARAEALNGELK
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
IATDVLAHDLKSPLTRLLSALDRASARAEDAEALAAVEQAEAEARRVLSIIDTALGISKA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EAGFGRESFTPVDLGAMLETIAEIYAPVVEEEGRRMEVQAPPGLVVPIHRQLMDQAIGNL
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHHHHHH
LDNTIRYGAGAISLAVEPRDGAMAISVADEGPGIPQHQHEEALRRFGRLDEARGGWGAGL
HHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCHHCCCCCCHHH
GLALVEAVAHLHGGRVELAENRQSRSGQPGLKVTLVLGQRAPGGGDSG
HHHHHHHHHHHCCCCEEEHHCCCCCCCCCCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MLRGMLRSTTVRFAALVFLLQVVAAAFMLGGLGAVMRQQSRAQALDTVETLRDDLMATTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QGGERQLVEAIRLRLANEVGRGVVVALVDPSGRLVEGNLARMPDDGFAVHLNRVASVVNV
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCHHCCCCCCHHHHHHHHHHHHHH
RRRNHAADEAALIVAARLPGGQLLLAGTVVESDRQFLALLERASIATLALSLLLAGLASF
HHHCCCCCHHEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATRQIVQRLRGTVATLEAVGAGDLARRVPPDGSGDAFSRLGEEVNRALARAEALNGELK
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
IATDVLAHDLKSPLTRLLSALDRASARAEDAEALAAVEQAEAEARRVLSIIDTALGISKA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EAGFGRESFTPVDLGAMLETIAEIYAPVVEEEGRRMEVQAPPGLVVPIHRQLMDQAIGNL
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHHHHHH
LDNTIRYGAGAISLAVEPRDGAMAISVADEGPGIPQHQHEEALRRFGRLDEARGGWGAGL
HHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCHHCCCCCCHHH
GLALVEAVAHLHGGRVELAENRQSRSGQPGLKVTLVLGQRAPGGGDSG
HHHHHHHHHHHCCCCEEEHHCCCCCCCCCCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]