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The map label for this gene is kdpE [H]

Identifier: 87199528

GI number: 87199528

Start: 1553514

End: 1554188

Strand: Reverse

Name: kdpE [H]

Synonym: Saro_1510

Alternate gene names: 87199528

Gene position: 1554188-1553514 (Counterclockwise)

Preceding gene: 87199529

Following gene: 87199527

Centisome position: 43.64

GC content: 60.59

Gene sequence:

>675_bases
ATGAGCACGGTCCTGTGCATCGACGATGAACCAGCCATTCTGCGCTTGCTGTCAGTCGTGCTCGCAGCCGATGGACATGA
AGTTATGACGGCTACCGCTGGTCGCGAAGCCCTCACGATCATCGGTCGTGGCGCCGTTGATGCGGTGTTGCTCGACCTCG
GCTTGGCCGACCGCGACGGGCTGGAACTGATTCCAGCAATCCGCGCCATAACGGCAGTACCAATCCTGGTCATCTCGGCC
CGGGGCGAAGTGGCCGAGAAAGTTACTGCGCTCGACCTCGGCGCCGCAGACTATATCACCAAGCCCTTCGACGGAGACGA
AGTACGTGCCAGACTCCGCGTCGCCCTCCGGCAGGGCGCAAAGTCGCTGACGCCTGACGGGGTCATCTGCCATGGCCCGA
TCCGCATGAATCCAGAACGACACGAGGCCGAGGTATCCGGCCGACCATTATCGCTGACGCCCAAGGAATATGCACTCCTC
AAAGCCCTCATCGAGGCCAATGGACGAGTGCTTACCCACGCCGCTCTGCTCGAACGCGTCTGGGGCAAAGCGCATCGGCA
AGACGTCGAATACCTGCGTGTTACAATCCGAGCATTGCGGCTGAAGATTGAAGAAGATCCGGCGCGCCCCATCGTAATTC
GAAACGAACCCGGGGTTGGCTATCGCTTGGGATAG

Upstream 100 bases:

>100_bases
GGTTTGGCGATGTCATGGGCATGGCCGTCACGGTTACTTCCGCGCCTTCTGGTGGGGCGCTCTTCACCGTTGCCATGCCG
CGCGCCGGGCGAGCCGGAAC

Downstream 100 bases:

>100_bases
TGTCGCCAGAAGCTGGTCATTGTCGTCGCGTGCCGCTCGGACACCAAGTTTCGCGATTCCGAATTGAGGGGGTAAGATGG
CGGGCATGAGACGCAGGCTC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MSTVLCIDDEPAILRLLSVVLAADGHEVMTATAGREALTIIGRGAVDAVLLDLGLADRDGLELIPAIRAITAVPILVISA
RGEVAEKVTALDLGAADYITKPFDGDEVRARLRVALRQGAKSLTPDGVICHGPIRMNPERHEAEVSGRPLSLTPKEYALL
KALIEANGRVLTHAALLERVWGKAHRQDVEYLRVTIRALRLKIEEDPARPIVIRNEPGVGYRLG

Sequences:

>Translated_224_residues
MSTVLCIDDEPAILRLLSVVLAADGHEVMTATAGREALTIIGRGAVDAVLLDLGLADRDGLELIPAIRAITAVPILVISA
RGEVAEKVTALDLGAADYITKPFDGDEVRARLRVALRQGAKSLTPDGVICHGPIRMNPERHEAEVSGRPLSLTPKEYALL
KALIEANGRVLTHAALLERVWGKAHRQDVEYLRVTIRALRLKIEEDPARPIVIRNEPGVGYRLG
>Mature_223_residues
STVLCIDDEPAILRLLSVVLAADGHEVMTATAGREALTIIGRGAVDAVLLDLGLADRDGLELIPAIRAITAVPILVISAR
GEVAEKVTALDLGAADYITKPFDGDEVRARLRVALRQGAKSLTPDGVICHGPIRMNPERHEAEVSGRPLSLTPKEYALLK
ALIEANGRVLTHAALLERVWGKAHRQDVEYLRVTIRALRLKIEEDPARPIVIRNEPGVGYRLG

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=40.3587443946188, Blast_Score=160, Evalue=5e-41,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=31.25, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788394, Length=219, Percent_Identity=31.9634703196347, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=32.8767123287671, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=32.579185520362, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=30.7692307692308, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.0748898678414, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=27.7272727272727, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=28.125, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI2367329, Length=189, Percent_Identity=30.6878306878307, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=27.1551724137931, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=35.5932203389831, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=35.9649122807018, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=25.7510729613734, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788905, Length=118, Percent_Identity=33.8983050847458, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=30.5343511450382, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24218; Mature: 24086

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVLCIDDEPAILRLLSVVLAADGHEVMTATAGREALTIIGRGAVDAVLLDLGLADRDG
CCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCHHHHHHHHCCCCCCCC
LELIPAIRAITAVPILVISARGEVAEKVTALDLGAADYITKPFDGDEVRARLRVALRQGA
HHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHCC
KSLTPDGVICHGPIRMNPERHEAEVSGRPLSLTPKEYALLKALIEANGRVLTHAALLERV
CCCCCCCEEEECCEECCCCHHHHHCCCCCEEECHHHHHHHHHHHHCCCCEEHHHHHHHHH
WGKAHRQDVEYLRVTIRALRLKIEEDPARPIVIRNEPGVGYRLG
HHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCEECC
>Mature Secondary Structure 
STVLCIDDEPAILRLLSVVLAADGHEVMTATAGREALTIIGRGAVDAVLLDLGLADRDG
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCHHHHHHHHCCCCCCCC
LELIPAIRAITAVPILVISARGEVAEKVTALDLGAADYITKPFDGDEVRARLRVALRQGA
HHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHCC
KSLTPDGVICHGPIRMNPERHEAEVSGRPLSLTPKEYALLKALIEANGRVLTHAALLERV
CCCCCCCEEEECCEECCCCHHHHHCCCCCEEECHHHHHHHHHHHHCCCCEEHHHHHHHHH
WGKAHRQDVEYLRVTIRALRLKIEEDPARPIVIRNEPGVGYRLG
HHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]