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The map label for this gene is tas [H]

Identifier: 87199375

GI number: 87199375

Start: 1399440

End: 1400456

Strand: Direct

Name: tas [H]

Synonym: Saro_1354

Alternate gene names: 87199375

Gene position: 1399440-1400456 (Clockwise)

Preceding gene: 87199374

Following gene: 87199376

Centisome position: 39.29

GC content: 63.13

Gene sequence:

>1017_bases
ATGCAGTATCGTCGCCTCGGCCGCTCGGCCATCGTCGTCTCGGACATCTGCATGGGGACGATGACCTTCGGCAGCCAGGT
AAGCGAAGCGGAGGCGCTCAGGGTTCTCGACCGGTCCTACGATGCCGGCATCAACTTCTACGATACTGCTGAAGGCTACC
CGGTTCCGCCCGATGTCAAATGGGTTGGCAGGACCGAGGAAATCGTTGGCAAGTGGCTCAAGACCAAGCCGCGCGATGCC
ATTGTGCTTGCGACCAAGGTTTCCGGTCCCAGCCATGTCTGGTTCCGTTCGCCATGCCGCGAAGGGATGACCGCGCTTGA
CCGCCACAACATCGTGCGTGCGATCGAAGGCAGCCTGCTTCGGCTGGGTACCGACTACATCGACCTCTACCAGACGCATT
GGCCGGATCACGACACGTCCTACGACGAGACGATGGAAGTGCTGGACGAGCTGGTCCGGGCGGGCAAGGTCCGCATCACC
GGCTGCTCGAACGAGACGAGCTGGGGCCTGATGAAGTCTTTGGCCGCCGCCGAGCGGCTTGGCACGGCACGCTACCAGAC
CATCCAGAACAACTTCAGTCTGAACAACCGCCGCTTCGAGGACGAGCTGGCTCAGGTCTGCCGGAAGGAAGGCGTCAGCC
TCATCCCCTATTCGCCAATTGCCGGCGGGGTTCTTTCAGGCAAGTACCTGAACGGCCAGCGGCCCGATGGAGCGCGCTTC
TCGCGCTACCTGGCGATGGAGGGCCGTCAGGCGGAAATGGGCAAGCGCTTCGTCAACGACCGCACCCTTGCCGCGACCGA
GCGCTTCATGGGCATTGCCGCGGAAGCCGGCCTCGACCCGGTGACAATGGCAGTCGCCTGGTCCAAGCAGCACGATTTCG
TCGCCTCGACGATCGTTGGCGTTGGCGCGGAAGACCAGCTCGCCCCGATCCTGGCTGCCGCCGACCTCGAGCTGTCGCAA
GAGGTTCTGCGGGCAATCGACAAGGTTTCCCGCGAAATCCGTTACCCGATGGGGTGA

Upstream 100 bases:

>100_bases
TTCCCGGCAAGTGCGGCGAAGGCGGCAATGACGGAAGCGGCCGAGTTCGCCGTCGCCCGGAGATTCTGAAGCCCCCCTCG
AACAGATAGGTTGGACCCTG

Downstream 100 bases:

>100_bases
GGGCGGGCGCGGCTACTTGCGGCGACCGAAGCGGCGCCACAGCCAGTAGCAGCTTCCCGCCGAGAACGCGCAGGCTCCCA
GGATCGCGGCGCCGATCACG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MQYRRLGRSAIVVSDICMGTMTFGSQVSEAEALRVLDRSYDAGINFYDTAEGYPVPPDVKWVGRTEEIVGKWLKTKPRDA
IVLATKVSGPSHVWFRSPCREGMTALDRHNIVRAIEGSLLRLGTDYIDLYQTHWPDHDTSYDETMEVLDELVRAGKVRIT
GCSNETSWGLMKSLAAAERLGTARYQTIQNNFSLNNRRFEDELAQVCRKEGVSLIPYSPIAGGVLSGKYLNGQRPDGARF
SRYLAMEGRQAEMGKRFVNDRTLAATERFMGIAAEAGLDPVTMAVAWSKQHDFVASTIVGVGAEDQLAPILAAADLELSQ
EVLRAIDKVSREIRYPMG

Sequences:

>Translated_338_residues
MQYRRLGRSAIVVSDICMGTMTFGSQVSEAEALRVLDRSYDAGINFYDTAEGYPVPPDVKWVGRTEEIVGKWLKTKPRDA
IVLATKVSGPSHVWFRSPCREGMTALDRHNIVRAIEGSLLRLGTDYIDLYQTHWPDHDTSYDETMEVLDELVRAGKVRIT
GCSNETSWGLMKSLAAAERLGTARYQTIQNNFSLNNRRFEDELAQVCRKEGVSLIPYSPIAGGVLSGKYLNGQRPDGARF
SRYLAMEGRQAEMGKRFVNDRTLAATERFMGIAAEAGLDPVTMAVAWSKQHDFVASTIVGVGAEDQLAPILAAADLELSQ
EVLRAIDKVSREIRYPMG
>Mature_338_residues
MQYRRLGRSAIVVSDICMGTMTFGSQVSEAEALRVLDRSYDAGINFYDTAEGYPVPPDVKWVGRTEEIVGKWLKTKPRDA
IVLATKVSGPSHVWFRSPCREGMTALDRHNIVRAIEGSLLRLGTDYIDLYQTHWPDHDTSYDETMEVLDELVRAGKVRIT
GCSNETSWGLMKSLAAAERLGTARYQTIQNNFSLNNRRFEDELAQVCRKEGVSLIPYSPIAGGVLSGKYLNGQRPDGARF
SRYLAMEGRQAEMGKRFVNDRTLAATERFMGIAAEAGLDPVTMAVAWSKQHDFVASTIVGVGAEDQLAPILAAADLELSQ
EVLRAIDKVSREIRYPMG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=337, Percent_Identity=28.7833827893175, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI27436964, Length=350, Percent_Identity=28.2857142857143, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI4504825, Length=335, Percent_Identity=28.6567164179104, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI27436962, Length=350, Percent_Identity=28.2857142857143, Blast_Score=128, Evalue=6e-30,
Organism=Homo sapiens, GI27436966, Length=350, Percent_Identity=28, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI27436971, Length=336, Percent_Identity=28.5714285714286, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI41327764, Length=214, Percent_Identity=29.4392523364486, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI41152114, Length=211, Percent_Identity=28.436018957346, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI223718702, Length=211, Percent_Identity=28.436018957346, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1789199, Length=360, Percent_Identity=42.7777777777778, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI87081735, Length=336, Percent_Identity=33.6309523809524, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1788070, Length=335, Percent_Identity=28.955223880597, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789375, Length=337, Percent_Identity=27.299703264095, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788081, Length=205, Percent_Identity=30.2439024390244, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=347, Percent_Identity=25.6484149855908, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=315, Percent_Identity=26.3492063492064, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=356, Percent_Identity=27.8089887640449, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6323998, Length=337, Percent_Identity=25.2225519287834, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=256, Percent_Identity=24.609375, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321052, Length=172, Percent_Identity=33.7209302325581, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24646159, Length=221, Percent_Identity=29.8642533936652, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24640980, Length=360, Percent_Identity=22.7777777777778, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI45549126, Length=360, Percent_Identity=22.7777777777778, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646155, Length=171, Percent_Identity=30.9941520467836, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 37562; Mature: 37562

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYRRLGRSAIVVSDICMGTMTFGSQVSEAEALRVLDRSYDAGINFYDTAEGYPVPPDVK
CCHHHHCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCE
WVGRTEEIVGKWLKTKPRDAIVLATKVSGPSHVWFRSPCREGMTALDRHNIVRAIEGSLL
ECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHCHHH
RLGTDYIDLYQTHWPDHDTSYDETMEVLDELVRAGKVRITGCSNETSWGLMKSLAAAERL
HHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
GTARYQTIQNNFSLNNRRFEDELAQVCRKEGVSLIPYSPIAGGVLSGKYLNGQRPDGARF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCHHHH
SRYLAMEGRQAEMGKRFVNDRTLAATERFMGIAAEAGLDPVTMAVAWSKQHDFVASTIVG
HHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHC
VGAEDQLAPILAAADLELSQEVLRAIDKVSREIRYPMG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQYRRLGRSAIVVSDICMGTMTFGSQVSEAEALRVLDRSYDAGINFYDTAEGYPVPPDVK
CCHHHHCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCE
WVGRTEEIVGKWLKTKPRDAIVLATKVSGPSHVWFRSPCREGMTALDRHNIVRAIEGSLL
ECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHCHHH
RLGTDYIDLYQTHWPDHDTSYDETMEVLDELVRAGKVRITGCSNETSWGLMKSLAAAERL
HHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
GTARYQTIQNNFSLNNRRFEDELAQVCRKEGVSLIPYSPIAGGVLSGKYLNGQRPDGARF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCHHHH
SRYLAMEGRQAEMGKRFVNDRTLAATERFMGIAAEAGLDPVTMAVAWSKQHDFVASTIVG
HHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHC
VGAEDQLAPILAAADLELSQEVLRAIDKVSREIRYPMG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]