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The map label for this gene is iorA [H]

Identifier: 87199367

GI number: 87199367

Start: 1389434

End: 1389961

Strand: Direct

Name: iorA [H]

Synonym: Saro_1346

Alternate gene names: 87199367

Gene position: 1389434-1389961 (Clockwise)

Preceding gene: 87199365

Following gene: 87199368

Centisome position: 39.01

GC content: 67.8

Gene sequence:

>528_bases
ATGACGAAGCTCAGGGTCAACGGTGCGGAGCGAGAGGTCAAGTCGGGTTCCGATACGCCGCTGCTCTACGTCCTGCGCAA
CGAGCTGGGCGTGATGACCCCGAAGTTCGGGTGCGGCATGGCGCAGTGCGGGGCCTGCTCGGTGCTGGTCGACGGCGAGG
AGACGCGGGCCTGCGTGACCCCGGTTGCCGCCATCGAGGGCAAGGAAGTGACTACGGTCGATGGCCTCCCCGCACGCTGG
GCCGCACAGCGCGGGCTTTCGGCGGAGCAGGCGGCCGGCAAGCTCCATCCGGTGCAGGAAGCCTGGATCGCGGAGCAGGT
GCCGCAGTGCGGGATCTGCCAGTTCGGCATGATGATCAAGATTACCGAACTGCTCGAGGCCAACCCCAAGCCCACCGATG
GCGATATCAAGGAGGCGCTGACCACTTCCGGCCCTTCGCCCCACCTGTGCCGCTGCGGCAGCTACGCCGCGATCCTGGAA
GGCGCCCATCGCGCCGCGCGGCTCATGGCCGAAGGAGGTGCGAAGTGA

Upstream 100 bases:

>100_bases
AACTGCCTGCAATCATTGGTGGTCTCAGGCCTGGAGCGGCGCTATCTGGCGTCTGGAATAGGGTGCGGGCAGATTGTCGG
CGCACGCCGGGGAGACGGAC

Downstream 100 bases:

>100_bases
GCGGAGCCCTTTCCATCCACGGCGCGACGCTCAGCCGCCGGGCCTTTGTCGGTGCCGGGGGCGCGTTGGTCGTCGCGCTC
GGCCTGCCGGCCAGCGGCGC

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTKLRVNGAEREVKSGSDTPLLYVLRNELGVMTPKFGCGMAQCGACSVLVDGEETRACVTPVAAIEGKEVTTVDGLPARW
AAQRGLSAEQAAGKLHPVQEAWIAEQVPQCGICQFGMMIKITELLEANPKPTDGDIKEALTTSGPSPHLCRCGSYAAILE
GAHRAARLMAEGGAK

Sequences:

>Translated_175_residues
MTKLRVNGAEREVKSGSDTPLLYVLRNELGVMTPKFGCGMAQCGACSVLVDGEETRACVTPVAAIEGKEVTTVDGLPARW
AAQRGLSAEQAAGKLHPVQEAWIAEQVPQCGICQFGMMIKITELLEANPKPTDGDIKEALTTSGPSPHLCRCGSYAAILE
GAHRAARLMAEGGAK
>Mature_174_residues
TKLRVNGAEREVKSGSDTPLLYVLRNELGVMTPKFGCGMAQCGACSVLVDGEETRACVTPVAAIEGKEVTTVDGLPARWA
AQRGLSAEQAAGKLHPVQEAWIAEQVPQCGICQFGMMIKITELLEANPKPTDGDIKEALTTSGPSPHLCRCGSYAAILEG
AHRAARLMAEGGAK

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=173, Percent_Identity=32.3699421965318, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1786480, Length=178, Percent_Identity=33.7078651685393, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1789232, Length=155, Percent_Identity=34.8387096774194, Blast_Score=80, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17540638, Length=170, Percent_Identity=34.1176470588235, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17539860, Length=169, Percent_Identity=29.585798816568, Blast_Score=76, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI32566215, Length=169, Percent_Identity=28.9940828402367, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17737937, Length=167, Percent_Identity=33.5329341317365, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 18436; Mature: 18305

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLRVNGAEREVKSGSDTPLLYVLRNELGVMTPKFGCGMAQCGACSVLVDGEETRACVT
CCEEECCCCHHHHCCCCCCCEEEEEECHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHC
PVAAIEGKEVTTVDGLPARWAAQRGLSAEQAAGKLHPVQEAWIAEQVPQCGICQFGMMIK
HHHHCCCCEEEEECCCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
ITELLEANPKPTDGDIKEALTTSGPSPHLCRCGSYAAILEGAHRAARLMAEGGAK
HHHHHHCCCCCCCCHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKLRVNGAEREVKSGSDTPLLYVLRNELGVMTPKFGCGMAQCGACSVLVDGEETRACVT
CEEECCCCHHHHCCCCCCCEEEEEECHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHC
PVAAIEGKEVTTVDGLPARWAAQRGLSAEQAAGKLHPVQEAWIAEQVPQCGICQFGMMIK
HHHHCCCCEEEEECCCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
ITELLEANPKPTDGDIKEALTTSGPSPHLCRCGSYAAILEGAHRAARLMAEGGAK
HHHHHHCCCCCCCCHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]