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The map label for this gene is sucD [H]

Identifier: 87199203

GI number: 87199203

Start: 1222937

End: 1223827

Strand: Reverse

Name: sucD [H]

Synonym: Saro_1181

Alternate gene names: 87199203

Gene position: 1223827-1222937 (Counterclockwise)

Preceding gene: 87199204

Following gene: 87199202

Centisome position: 34.36

GC content: 64.53

Gene sequence:

>891_bases
ATGAGCATTCTCGTCGACAAGAATACCAAGGTCATCACCCAGGGGATGACGGGTGCCACCGGCACCTTCCACACCGAACA
GGCGCTGGCATACGGCACCCAGATGGTCGGCGGCGTGACGCCGGGCAAGGGCGGCACGACCCACATCGGCCTGCCCAACT
TCAACACCGTTGCCGAAGCCAAGGCCGCGACCGGCGCGACTGCTTCGTGCATCTACGTTCCGCCGCCGTTCGCTGCCGAT
TCGATCCTCGAGGCGATCGACGCCGAGATGGAACTGATCGTCTGCATCACCGAAGGCATCCCGGTCCTCGACATGGTCAA
GGTGAAGCGCGCCCTTTCCGGTTCGAAGAGCCGCCTGATCGGTCCCAACTGCCCCGGCGTCCTGACCCCGAACGAATGCA
AGATCGGCATCATGCCGGGCTCGATCTTCAAGAAGGGTTCGGTCGGCGTCGTCTCGCGTTCGGGCACCCTCACCTATGAA
GCGGTGTTCCAGACCTCGAACATCGGCCTGGGCCAGACCACCGCTGTCGGCATCGGCGGCGACCCGGTCAACGGCACCAA
CTTCATCGACGTGCTGGAACTGTTCCTGGCCGACGACGAAACCAAGTCGATCATCATGATCGGCGAAATCGGCGGTTCGG
CCGAAGAAGAAGCGGCACAGTTCCTCAAGGACGAAGCCAAGCGCGGTCGCAAGAAGCCGATGGTCGGTTTCATCGCCGGT
CGCACGGCGCCTCCGGGCCGCCGCATGGGCCACGCCGGCGCGATCGTCTCGGGCGGCCAGGGCGGCGCCGAAGACAAGAT
CGCGGCGATGGAAGAGGCCGGCATCCGTGTCAGCCCCTCGCCTTCGCTGCTCGGCGAAACGCTTGCCGAAGTGCTGAAGG
AACGCGTCTGA

Upstream 100 bases:

>100_bases
TTTGACAGTTGCGCCCCATCCTCCCCTGGGGCCACCTGACTGCCGAGCCGCCCGTCCCGCAATCCAGACGCGACGGGTGG
CAGAACCGGAAAGGAACGAC

Downstream 100 bases:

>100_bases
TCGCGTGAATGCCATCGCCCGGTAGGCCACCTTACGTAGGGGGCCGCCGGGCGGTTGCTTCAAGATTTTCCGGTAGGCGA
CCGAAACGGATGCGGCCTGC

Product: succinyl-CoA synthetase (ADP-forming) subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSILVDKNTKVITQGMTGATGTFHTEQALAYGTQMVGGVTPGKGGTTHIGLPNFNTVAEAKAATGATASCIYVPPPFAAD
SILEAIDAEMELIVCITEGIPVLDMVKVKRALSGSKSRLIGPNCPGVLTPNECKIGIMPGSIFKKGSVGVVSRSGTLTYE
AVFQTSNIGLGQTTAVGIGGDPVNGTNFIDVLELFLADDETKSIIMIGEIGGSAEEEAAQFLKDEAKRGRKKPMVGFIAG
RTAPPGRRMGHAGAIVSGGQGGAEDKIAAMEEAGIRVSPSPSLLGETLAEVLKERV

Sequences:

>Translated_296_residues
MSILVDKNTKVITQGMTGATGTFHTEQALAYGTQMVGGVTPGKGGTTHIGLPNFNTVAEAKAATGATASCIYVPPPFAAD
SILEAIDAEMELIVCITEGIPVLDMVKVKRALSGSKSRLIGPNCPGVLTPNECKIGIMPGSIFKKGSVGVVSRSGTLTYE
AVFQTSNIGLGQTTAVGIGGDPVNGTNFIDVLELFLADDETKSIIMIGEIGGSAEEEAAQFLKDEAKRGRKKPMVGFIAG
RTAPPGRRMGHAGAIVSGGQGGAEDKIAAMEEAGIRVSPSPSLLGETLAEVLKERV
>Mature_295_residues
SILVDKNTKVITQGMTGATGTFHTEQALAYGTQMVGGVTPGKGGTTHIGLPNFNTVAEAKAATGATASCIYVPPPFAADS
ILEAIDAEMELIVCITEGIPVLDMVKVKRALSGSKSRLIGPNCPGVLTPNECKIGIMPGSIFKKGSVGVVSRSGTLTYEA
VFQTSNIGLGQTTAVGIGGDPVNGTNFIDVLELFLADDETKSIIMIGEIGGSAEEEAAQFLKDEAKRGRKKPMVGFIAGR
TAPPGRRMGHAGAIVSGGQGGAEDKIAAMEEAGIRVSPSPSLLGETLAEVLKERV

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=294, Percent_Identity=66.6666666666667, Blast_Score=342, Evalue=3e-94,
Organism=Homo sapiens, GI38569423, Length=266, Percent_Identity=30.4511278195489, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI38569421, Length=266, Percent_Identity=30.4511278195489, Blast_Score=81, Evalue=9e-16,
Organism=Escherichia coli, GI1786949, Length=293, Percent_Identity=67.2354948805461, Blast_Score=394, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17550194, Length=289, Percent_Identity=62.2837370242215, Blast_Score=349, Evalue=8e-97,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=61.986301369863, Blast_Score=346, Evalue=7e-96,
Organism=Caenorhabditis elegans, GI17557344, Length=263, Percent_Identity=28.5171102661597, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=269, Percent_Identity=28.996282527881, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324716, Length=294, Percent_Identity=52.3809523809524, Blast_Score=289, Evalue=5e-79,
Organism=Drosophila melanogaster, GI21356559, Length=290, Percent_Identity=60.3448275862069, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI28574296, Length=294, Percent_Identity=63.6054421768708, Blast_Score=343, Evalue=7e-95,
Organism=Drosophila melanogaster, GI281363477, Length=234, Percent_Identity=32.0512820512821, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281363475, Length=234, Percent_Identity=32.0512820512821, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281363473, Length=234, Percent_Identity=32.0512820512821, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30459; Mature: 30328

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVDKNTKVITQGMTGATGTFHTEQALAYGTQMVGGVTPGKGGTTHIGLPNFNTVAEA
CEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHH
KAATGATASCIYVPPPFAADSILEAIDAEMELIVCITEGIPVLDMVKVKRALSGSKSRLI
HHCCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGVLTPNECKIGIMPGSIFKKGSVGVVSRSGTLTYEAVFQTSNIGLGQTTAVGIGG
CCCCCCCCCCCCCEEEEECCHHCCCCCCEEEECCCCEEEEEEEEECCCCCCCEEEEECCC
DPVNGTNFIDVLELFLADDETKSIIMIGEIGGSAEEEAAQFLKDEAKRGRKKPMVGFIAG
CCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
RTAPPGRRMGHAGAIVSGGQGGAEDKIAAMEEAGIRVSPSPSLLGETLAEVLKERV
CCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILVDKNTKVITQGMTGATGTFHTEQALAYGTQMVGGVTPGKGGTTHIGLPNFNTVAEA
EEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHH
KAATGATASCIYVPPPFAADSILEAIDAEMELIVCITEGIPVLDMVKVKRALSGSKSRLI
HHCCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGVLTPNECKIGIMPGSIFKKGSVGVVSRSGTLTYEAVFQTSNIGLGQTTAVGIGG
CCCCCCCCCCCCCEEEEECCHHCCCCCCEEEECCCCEEEEEEEEECCCCCCCEEEEECCC
DPVNGTNFIDVLELFLADDETKSIIMIGEIGGSAEEEAAQFLKDEAKRGRKKPMVGFIAG
CCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
RTAPPGRRMGHAGAIVSGGQGGAEDKIAAMEEAGIRVSPSPSLLGETLAEVLKERV
CCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]