Click here to switch to the map view.

The map label for this gene is map [H]

Identifier: 87199132

GI number: 87199132

Start: 1157759

End: 1158610

Strand: Reverse

Name: map [H]

Synonym: Saro_1110

Alternate gene names: 87199132

Gene position: 1158610-1157759 (Counterclockwise)

Preceding gene: 87199133

Following gene: 87199131

Centisome position: 32.53

GC content: 65.85

Gene sequence:

>852_bases
ATGGATCGCTACATGGCGCCCATGACCGAATACGTTACAGTCGAAGACCACAGCGTCCTGCCGCGCGACGGGACCATCAA
GCTCCATGGCCCCGCCGGCTTCGAGGGCATGCGCAAGGCGGGCCGGCTGGCCGCCGAGATTCTCGACGCCCTGGCCCCGC
TGGTCCAGCCCGGCGTGCGCACGGACTACCTCGACGATGTCGTGCGCCAGATGACGCTCGATGCCGGAGCGGTACCCGCG
ACGATGGGTTACCGCGGCTACGCGCACTCCTCGTGCATTTCGATAAACCACGTCGTCTGCCACGGCATTCCGTCGGACAA
GACGCTCAAGGACGGAGACATCGTCAATATCGACGTGACCCCGCTGCTCGATGGTTGGCACGGCGATTCCAGCCGCATGT
ACCTCGTCGGCGACGTGCCGCTGAAAGCGCGCCGCCTTGTCGACGTGACCTATGAATGCCTGATGATCGGCATCGAGCAG
GCCAAGCCCGGCGCCCGCCTCGGCGACATTGGCGCGGCCATCCAGGCCCATGCCGAAAAGCAGCGCTATGGCGTCGTGCG
CGAGTTCTGCGGCCACGGCCTCGGACGCCTGTTCCACGATGCGCCGGAAGTGGTCCACGCCGCCCGCGCCGGAACCGGAC
CGGAACTTCGTCCTGGCATGTTCTTCACGATCGAGCCCATGATCAATCTCGGCAAGCCCGGAGTGAAGATCCTCGAGGAT
GGCTGGACAGCGGTCACGCGCGACCGCTCGCTCTCGGCGCAGTTCGAGCACTCGATCGGGATCACCGAGGACGGCTGCGA
AATCTTCACCGCCAGCCCCAAGGGCCTCGACAAGCCGCCCTACGCGGTCTGA

Upstream 100 bases:

>100_bases
CCGGTCTCCGCCAAGGTCCTCGCGGCCGTGAAGCCCGAATTCAAGGGCACCTTCGTCGCACGATGAAACACGCCCGCGCG
AATGGCTCGCATTTTGGGCG

Downstream 100 bases:

>100_bases
TCGGGTGGCTGGCGCTCCCTGCCTAAAAATAAGGCAGACGTTGCGTAAAATTTGTGCACGATTTGAACAATCGCGCGCAA
TGATACGAATGCAGCACCAA

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MDRYMAPMTEYVTVEDHSVLPRDGTIKLHGPAGFEGMRKAGRLAAEILDALAPLVQPGVRTDYLDDVVRQMTLDAGAVPA
TMGYRGYAHSSCISINHVVCHGIPSDKTLKDGDIVNIDVTPLLDGWHGDSSRMYLVGDVPLKARRLVDVTYECLMIGIEQ
AKPGARLGDIGAAIQAHAEKQRYGVVREFCGHGLGRLFHDAPEVVHAARAGTGPELRPGMFFTIEPMINLGKPGVKILED
GWTAVTRDRSLSAQFEHSIGITEDGCEIFTASPKGLDKPPYAV

Sequences:

>Translated_283_residues
MDRYMAPMTEYVTVEDHSVLPRDGTIKLHGPAGFEGMRKAGRLAAEILDALAPLVQPGVRTDYLDDVVRQMTLDAGAVPA
TMGYRGYAHSSCISINHVVCHGIPSDKTLKDGDIVNIDVTPLLDGWHGDSSRMYLVGDVPLKARRLVDVTYECLMIGIEQ
AKPGARLGDIGAAIQAHAEKQRYGVVREFCGHGLGRLFHDAPEVVHAARAGTGPELRPGMFFTIEPMINLGKPGVKILED
GWTAVTRDRSLSAQFEHSIGITEDGCEIFTASPKGLDKPPYAV
>Mature_283_residues
MDRYMAPMTEYVTVEDHSVLPRDGTIKLHGPAGFEGMRKAGRLAAEILDALAPLVQPGVRTDYLDDVVRQMTLDAGAVPA
TMGYRGYAHSSCISINHVVCHGIPSDKTLKDGDIVNIDVTPLLDGWHGDSSRMYLVGDVPLKARRLVDVTYECLMIGIEQ
AKPGARLGDIGAAIQAHAEKQRYGVVREFCGHGLGRLFHDAPEVVHAARAGTGPELRPGMFFTIEPMINLGKPGVKILED
GWTAVTRDRSLSAQFEHSIGITEDGCEIFTASPKGLDKPPYAV

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=256, Percent_Identity=44.53125, Blast_Score=232, Evalue=3e-61,
Organism=Homo sapiens, GI40385867, Length=265, Percent_Identity=38.1132075471698, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI1786364, Length=247, Percent_Identity=52.6315789473684, Blast_Score=267, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI71996291, Length=237, Percent_Identity=44.3037974683544, Blast_Score=209, Evalue=9e-55,
Organism=Saccharomyces cerevisiae, GI6323273, Length=254, Percent_Identity=41.3385826771654, Blast_Score=217, Evalue=2e-57,
Organism=Drosophila melanogaster, GI21355531, Length=260, Percent_Identity=42.3076923076923, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24583427, Length=247, Percent_Identity=41.7004048582996, Blast_Score=205, Evalue=3e-53,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30673; Mature: 30673

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRYMAPMTEYVTVEDHSVLPRDGTIKLHGPAGFEGMRKAGRLAAEILDALAPLVQPGVR
CCCCCCCHHHEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
TDYLDDVVRQMTLDAGAVPATMGYRGYAHSSCISINHVVCHGIPSDKTLKDGDIVNIDVT
HHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEECEEEEECCCCCCCCCCCCEEEEEEE
PLLDGWHGDSSRMYLVGDVPLKARRLVDVTYECLMIGIEQAKPGARLGDIGAAIQAHAEK
EEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QRYGVVREFCGHGLGRLFHDAPEVVHAARAGTGPELRPGMFFTIEPMINLGKPGVKILED
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHCCCCCCCEEEEC
GWTAVTRDRSLSAQFEHSIGITEDGCEIFTASPKGLDKPPYAV
CCEEEECCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MDRYMAPMTEYVTVEDHSVLPRDGTIKLHGPAGFEGMRKAGRLAAEILDALAPLVQPGVR
CCCCCCCHHHEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
TDYLDDVVRQMTLDAGAVPATMGYRGYAHSSCISINHVVCHGIPSDKTLKDGDIVNIDVT
HHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEECEEEEECCCCCCCCCCCCEEEEEEE
PLLDGWHGDSSRMYLVGDVPLKARRLVDVTYECLMIGIEQAKPGARLGDIGAAIQAHAEK
EEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QRYGVVREFCGHGLGRLFHDAPEVVHAARAGTGPELRPGMFFTIEPMINLGKPGVKILED
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHCCCCCCCEEEEC
GWTAVTRDRSLSAQFEHSIGITEDGCEIFTASPKGLDKPPYAV
CCEEEECCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]