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The map label for this gene is ispH [H]

Identifier: 87199109

GI number: 87199109

Start: 1129961

End: 1130929

Strand: Reverse

Name: ispH [H]

Synonym: Saro_1087

Alternate gene names: 87199109

Gene position: 1130929-1129961 (Counterclockwise)

Preceding gene: 87199119

Following gene: 87199108

Centisome position: 31.75

GC content: 68.42

Gene sequence:

>969_bases
ATGAACGCCAGCTTGCCAGACGCCGCGCCCCAGGGCGCCCCGCTCCGCCTCCTGATTGCCGCCCCGCGCGGGTTCTGCGC
GGGGGTCGACCGCGCGATCGAAATCGTCGAGCGCTCGCTCGAACGCTTTGGTGCACCGGTCTACGTCCGGCACGAAATCG
TCCACAACCGCTATGTCGTCGACGGGCTCAAGGCCAAGGGCGCGGTCTTCGTCGAGGAACTGGACCAGGTGCCCGATGGC
GCGCCAGTCGTCTTTTCGGCCCACGGCGTGCCCAAGGTCGTGCCCCAGACCGCGACCGAGCGCGGGCTCGACTGGCTCGA
CGCCACCTGCCCGCTGGTCAGCAAGGTCCACCGCCAGGCCGAGCGGCAGGTAGAGGCCGGGCGCCATATCCTGTTCGTCG
GCCACAAGGGGCACCCCGAAGTGATCGGTACGATGGGCCAGGTCCCCGAGGGCACGATCTCACTGGTCGAGACGGTCGAG
GACGTCGCAGGCCTCGACTTTCCCGAGGGCACGCCGCTCGCCTTCCTGACGCAGACCACGCTTTCGGTGGACGACACGGC
AGAGATCGTCGCCGCGCTCCACACCCGCTTCCCGCAAATCGTCGGGCCCAAGGCAGAGGACATCTGCTATGCCACGTCCA
ACCGCCAGGCCGCGGTCAAGGCAATCGCGGGCGAGTGCGACCTGCTGCTGGTGATCGGCGCCCCGAACAGCTCCAACTCG
CTGCGGCTGGTCGAAGTGGCTGAACGGCTCGGCACCCGCTCGCGCCTGATCCAGCGGGCGAGCGAGATCGAACCTGAATG
GCTCGATGGCGTCGAAACGCTCGGTCTCACCGCCGGCGCCTCGGCACCCGAAGTGCTGGTGCGCGAAGTCGTCGCCCGGA
TCGCCTCGCTCCGGCCGGTCACCGAGGAAACGGTGACCACGGCCGAAGAGAAGATGGTGTTCAAGCTGCCGCGCCAACTG
GTCGACTGA

Upstream 100 bases:

>100_bases
CTTGTGTCGCGGCGATCTGGCCGAGATTTGCGCCACCTCTACCCACCACAGCCGCTTTCGGCAATGGCAGGCGGGCGCGC
TTGCTGCTAAGGGGCGCGCG

Downstream 100 bases:

>100_bases
CGATGGCGGTCTATACCCAGATCGGCGCCGAGGACATGGCCGCGCTCGTCGCCGAGTTCGACGTGGGCGAACTCGTTTCG
GCCAAGGGCATCGCCGAGGG

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNASLPDAAPQGAPLRLLIAAPRGFCAGVDRAIEIVERSLERFGAPVYVRHEIVHNRYVVDGLKAKGAVFVEELDQVPDG
APVVFSAHGVPKVVPQTATERGLDWLDATCPLVSKVHRQAERQVEAGRHILFVGHKGHPEVIGTMGQVPEGTISLVETVE
DVAGLDFPEGTPLAFLTQTTLSVDDTAEIVAALHTRFPQIVGPKAEDICYATSNRQAAVKAIAGECDLLLVIGAPNSSNS
LRLVEVAERLGTRSRLIQRASEIEPEWLDGVETLGLTAGASAPEVLVREVVARIASLRPVTEETVTTAEEKMVFKLPRQL
VD

Sequences:

>Translated_322_residues
MNASLPDAAPQGAPLRLLIAAPRGFCAGVDRAIEIVERSLERFGAPVYVRHEIVHNRYVVDGLKAKGAVFVEELDQVPDG
APVVFSAHGVPKVVPQTATERGLDWLDATCPLVSKVHRQAERQVEAGRHILFVGHKGHPEVIGTMGQVPEGTISLVETVE
DVAGLDFPEGTPLAFLTQTTLSVDDTAEIVAALHTRFPQIVGPKAEDICYATSNRQAAVKAIAGECDLLLVIGAPNSSNS
LRLVEVAERLGTRSRLIQRASEIEPEWLDGVETLGLTAGASAPEVLVREVVARIASLRPVTEETVTTAEEKMVFKLPRQL
VD
>Mature_322_residues
MNASLPDAAPQGAPLRLLIAAPRGFCAGVDRAIEIVERSLERFGAPVYVRHEIVHNRYVVDGLKAKGAVFVEELDQVPDG
APVVFSAHGVPKVVPQTATERGLDWLDATCPLVSKVHRQAERQVEAGRHILFVGHKGHPEVIGTMGQVPEGTISLVETVE
DVAGLDFPEGTPLAFLTQTTLSVDDTAEIVAALHTRFPQIVGPKAEDICYATSNRQAAVKAIAGECDLLLVIGAPNSSNS
LRLVEVAERLGTRSRLIQRASEIEPEWLDGVETLGLTAGASAPEVLVREVVARIASLRPVTEETVTTAEEKMVFKLPRQL
VD

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=308, Percent_Identity=53.2467532467532, Blast_Score=343, Evalue=1e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 34599; Mature: 34599

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASLPDAAPQGAPLRLLIAAPRGFCAGVDRAIEIVERSLERFGAPVYVRHEIVHNRYVV
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCHHHE
DGLKAKGAVFVEELDQVPDGAPVVFSAHGVPKVVPQTATERGLDWLDATCPLVSKVHRQA
ECCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
ERQVEAGRHILFVGHKGHPEVIGTMGQVPEGTISLVETVEDVAGLDFPEGTPLAFLTQTT
HHHHHCCCEEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEE
LSVDDTAEIVAALHTRFPQIVGPKAEDICYATSNRQAAVKAIAGECDLLLVIGAPNSSNS
CCCCHHHHHHHHHHHHCHHHCCCCCHHEEEECCCCHHHHHHHCCCCCEEEEEECCCCCCC
LRLVEVAERLGTRSRLIQRASEIEPEWLDGVETLGLTAGASAPEVLVREVVARIASLRPV
CHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
TEETVTTAEEKMVFKLPRQLVD
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNASLPDAAPQGAPLRLLIAAPRGFCAGVDRAIEIVERSLERFGAPVYVRHEIVHNRYVV
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCHHHE
DGLKAKGAVFVEELDQVPDGAPVVFSAHGVPKVVPQTATERGLDWLDATCPLVSKVHRQA
ECCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
ERQVEAGRHILFVGHKGHPEVIGTMGQVPEGTISLVETVEDVAGLDFPEGTPLAFLTQTT
HHHHHCCCEEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEE
LSVDDTAEIVAALHTRFPQIVGPKAEDICYATSNRQAAVKAIAGECDLLLVIGAPNSSNS
CCCCHHHHHHHHHHHHCHHHCCCCCHHEEEECCCCHHHHHHHCCCCCEEEEEECCCCCCC
LRLVEVAERLGTRSRLIQRASEIEPEWLDGVETLGLTAGASAPEVLVREVVARIASLRPV
CHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
TEETVTTAEEKMVFKLPRQLVD
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA