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The map label for this gene is lepB [H]

Identifier: 87198931

GI number: 87198931

Start: 963464

End: 964369

Strand: Reverse

Name: lepB [H]

Synonym: Saro_0909

Alternate gene names: 87198931

Gene position: 964369-963464 (Counterclockwise)

Preceding gene: 87198932

Following gene: 87198930

Centisome position: 27.08

GC content: 67.33

Gene sequence:

>906_bases
TTGAACAACCAGATTTCCCGGCCGCCGGAACCCCTTTCCCCGCCCCCTCCACCGCCACACAGCGTCGACTGGTGGTCGGA
AATTCGCGGCCTCGTCGCCATGCTGCTGGCCGTGGTGCTGTTCCACAGCCTCGTCGCCAAGCCGTTCTACATTCCGTCGA
TCTCGATGATGCCGAACCTCCTCGTGGGGGACAGGCTGGTCGTGTCGAAGTATCCCTACGGCTGGTCGTGGGTCTCGGCA
TCGTTCCACGTCCTGCCGCGCGGCGAGCGGCGGATTCTGCCACAGACGCCCGAATACGGCGACGTCGTGATCGCCGTCCC
GCCCGACCGCGACGAGGACTACATCAAGCGCGTCGTTGCCCTGCCGGGCGACCGCATCACCGTGATCCACGGCCAGATCA
TCCTCAACGGCAAGCTCGTGCCCCAGCAGGCCGTGCCGCCCGTGCGGATCCCCGCCGATCCGAACCTCTCGTGCGACGGC
GCTCCGTGCTACGACATGTTCGAGCGCTATCGCACCCGCCTCGCAGACGGCCGCGAGATCTACGAGCTTCCCGCCTTCCG
CGAGACCCTGCCCAACGGCGCGAGCTACCTGATCATCGACCACATGGACCAGATGCTCGACAACTATCCCGAAACGGTGG
TTCCGCCGGGGCACGTCTTCCTGATGGGCGACAACCGCGATCATTCGGCCGACAGCCGTGCCCCGATCGAGGAAAAGGGC
CTGGGCGGGCCGGTGCCGCTCGCCAATGTCGGCGGCCGCGCGGAATTCGTGACCTTCTCGCTCGACGGCAGCGAAACGCT
CAACCCGCTGACGTGGCTCTCCGCCTTGCGCGACGGCCGCGCCTGGACCAGACTGCGCCCCGAAATCCGCCGCCAGCCCT
TGCCGGCGGGTGAAGGGGAGCCCTGA

Upstream 100 bases:

>100_bases
GCCACGAGGCCGTGGTCCACCTGACGCTCACCGACGATCACCCCTGGGCGCAGGCTTTCGTCGTGATCGAGGCCCGCCCG
CTTCCCGGAAGCACCCCAGC

Downstream 100 bases:

>100_bases
TCCGCATGGATGACATTGCCCCGGCGCGTCCCGCCGGCCCTACCGACATCAGCGACGACCTGGTCCGCCGCGAAGCCAAG
AAGGCGGCGGTGTGGCTTGG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNNQISRPPEPLSPPPPPPHSVDWWSEIRGLVAMLLAVVLFHSLVAKPFYIPSISMMPNLLVGDRLVVSKYPYGWSWVSA
SFHVLPRGERRILPQTPEYGDVVIAVPPDRDEDYIKRVVALPGDRITVIHGQIILNGKLVPQQAVPPVRIPADPNLSCDG
APCYDMFERYRTRLADGREIYELPAFRETLPNGASYLIIDHMDQMLDNYPETVVPPGHVFLMGDNRDHSADSRAPIEEKG
LGGPVPLANVGGRAEFVTFSLDGSETLNPLTWLSALRDGRAWTRLRPEIRRQPLPAGEGEP

Sequences:

>Translated_301_residues
MNNQISRPPEPLSPPPPPPHSVDWWSEIRGLVAMLLAVVLFHSLVAKPFYIPSISMMPNLLVGDRLVVSKYPYGWSWVSA
SFHVLPRGERRILPQTPEYGDVVIAVPPDRDEDYIKRVVALPGDRITVIHGQIILNGKLVPQQAVPPVRIPADPNLSCDG
APCYDMFERYRTRLADGREIYELPAFRETLPNGASYLIIDHMDQMLDNYPETVVPPGHVFLMGDNRDHSADSRAPIEEKG
LGGPVPLANVGGRAEFVTFSLDGSETLNPLTWLSALRDGRAWTRLRPEIRRQPLPAGEGEP
>Mature_301_residues
MNNQISRPPEPLSPPPPPPHSVDWWSEIRGLVAMLLAVVLFHSLVAKPFYIPSISMMPNLLVGDRLVVSKYPYGWSWVSA
SFHVLPRGERRILPQTPEYGDVVIAVPPDRDEDYIKRVVALPGDRITVIHGQIILNGKLVPQQAVPPVRIPADPNLSCDG
APCYDMFERYRTRLADGREIYELPAFRETLPNGASYLIIDHMDQMLDNYPETVVPPGHVFLMGDNRDHSADSRAPIEEKG
LGGPVPLANVGGRAEFVTFSLDGSETLNPLTWLSALRDGRAWTRLRPEIRRQPLPAGEGEP

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=280, Percent_Identity=32.1428571428571, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 33540; Mature: 33540

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQISRPPEPLSPPPPPPHSVDWWSEIRGLVAMLLAVVLFHSLVAKPFYIPSISMMPNL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCH
LVGDRLVVSKYPYGWSWVSASFHVLPRGERRILPQTPEYGDVVIAVPPDRDEDYIKRVVA
HHCCEEEEECCCCCEEEECCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
LPGDRITVIHGQIILNGKLVPQQAVPPVRIPADPNLSCDGAPCYDMFERYRTRLADGREI
CCCCEEEEEEEEEEECCEECCHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
YELPAFRETLPNGASYLIIDHMDQMLDNYPETVVPPGHVFLMGDNRDHSADSRAPIEEKG
HHCCHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHCC
LGGPVPLANVGGRAEFVTFSLDGSETLNPLTWLSALRDGRAWTRLRPEIRRQPLPAGEGE
CCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCHHHHCCHHHHCCCCCCCCCC
P
C
>Mature Secondary Structure
MNNQISRPPEPLSPPPPPPHSVDWWSEIRGLVAMLLAVVLFHSLVAKPFYIPSISMMPNL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCH
LVGDRLVVSKYPYGWSWVSASFHVLPRGERRILPQTPEYGDVVIAVPPDRDEDYIKRVVA
HHCCEEEEECCCCCEEEECCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
LPGDRITVIHGQIILNGKLVPQQAVPPVRIPADPNLSCDGAPCYDMFERYRTRLADGREI
CCCCEEEEEEEEEEECCEECCHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHH
YELPAFRETLPNGASYLIIDHMDQMLDNYPETVVPPGHVFLMGDNRDHSADSRAPIEEKG
HHCCHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHCC
LGGPVPLANVGGRAEFVTFSLDGSETLNPLTWLSALRDGRAWTRLRPEIRRQPLPAGEGE
CCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCHHHHCCHHHHCCCCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA