BacMap

Definition	Novosphingobium aromaticivorans DSM 12444 chromosome, complete genome.
Accession	NC_007794
Length	3,561,584

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The map label for this gene is ligD [H]

Identifier: 87198816

GI number: 87198816

Start: 843248

End: 844180

Strand: Reverse

Name: ligD [H]

Synonym: Saro_0794

Alternate gene names: 87198816

Gene position: 844180-843248 (Counterclockwise)

Preceding gene: 87198823

Following gene: 87198815

Centisome position: 23.7

GC content: 65.06

Gene sequence:

>933_bases
ATGCAGAATCTGCCGGGCAAGACGGCTTTCGTGACGGGCGGCGCCAGCGGCATCGGCCTGGGCATCGCCAAGGCGCTGCT
TGGCGCCGGGATGAACGTGACCATCGCGGACATCCGCCAGGACCACCTCGATTCGGCCGTGGCAGAGCTGGGCGGCGGCG
AGCGGGTGCTCGCGGTGAAGCTCGACGTGACCAATCGCGACCAGTTCGCCAAGGCAGCCGACGCCACCGAGGCGAAGTTC
GGCAAGATTCACCTGCTGGTGAACAATGCGGGCGTTGCCGTGGTCGGCCCGACCGAGCTGGCGACTTTTGCCGACTGGGA
CTGGGTCATGGGCGTGAACGTGAATGGCACGATCAACGGCATCGTCACCATCCTGCCCCGCATCCTCGCCCACGGCGAAG
GCGGCCATATCGTCTGCACCGCTTCGATGTCGGCGCTTGTGCCGGTTGCGGGAACGACGATCTATTCGGCCGGCAAGGCT
GCCGTGACCGCGATGATGGAATGCATGAGGCCCGAGCTTGAAGGCAGGGGCGTGATCTGCTCGGCATTCTGCCCCGGCGC
GGTCCAGTCGAACATTGCCGATGCCGCCAAGACCCGTCCGGCCGAGTTGGCTGACACCGGCTATGCCGAAGCCGACAAGC
GCCGCGCGGCCGGCGGCAACTTCATGCACTTGTACCAGACCAAGGAACAAGTCGGCGAGCGCGTGCTGGAAGGCATCCTC
AACGACGAACTCTATATCCTGACCCACGCAGAGTTCCTGACCGGGGTGGAAGAGCGCGGCCTTGCCACGACGGCGGCAGT
GCAGACCCACTTGCCCGAGAACCCGGAATACAAGGAGACCTTCGCAGCCCTGTTCCGCAATCCGGCGATCACCGACGAAA
TCGCCCGGCAGAACAAGCTGAAGGAAACCCGCAAGGCCGGGGTCGAGGCATGA

Upstream 100 bases:

>100_bases
TTAGTCTTGCATACAATTCCTCGCTGGTGAATACAAAAGGCGAAAAATGATTCCCGGCGCCGGTCGATGGCTGCCGGCAA
GGCACCAAAGGAGAGGATCG

Downstream 100 bases:

>100_bases
AGGACTTCGCGGGCCGTACCGCCTTCGTCACGGGCGGCGCCAATGGCGTCGGCATCGGCCTTGTCCGCCAGCTCCTCAAC
CAGGGGTGCAAGGTCGCCAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MQNLPGKTAFVTGGASGIGLGIAKALLGAGMNVTIADIRQDHLDSAVAELGGGERVLAVKLDVTNRDQFAKAADATEAKF
GKIHLLVNNAGVAVVGPTELATFADWDWVMGVNVNGTINGIVTILPRILAHGEGGHIVCTASMSALVPVAGTTIYSAGKA
AVTAMMECMRPELEGRGVICSAFCPGAVQSNIADAAKTRPAELADTGYAEADKRRAAGGNFMHLYQTKEQVGERVLEGIL
NDELYILTHAEFLTGVEERGLATTAAVQTHLPENPEYKETFAALFRNPAITDEIARQNKLKETRKAGVEA

Sequences:

>Translated_310_residues
MQNLPGKTAFVTGGASGIGLGIAKALLGAGMNVTIADIRQDHLDSAVAELGGGERVLAVKLDVTNRDQFAKAADATEAKF
GKIHLLVNNAGVAVVGPTELATFADWDWVMGVNVNGTINGIVTILPRILAHGEGGHIVCTASMSALVPVAGTTIYSAGKA
AVTAMMECMRPELEGRGVICSAFCPGAVQSNIADAAKTRPAELADTGYAEADKRRAAGGNFMHLYQTKEQVGERVLEGIL
NDELYILTHAEFLTGVEERGLATTAAVQTHLPENPEYKETFAALFRNPAITDEIARQNKLKETRKAGVEA
>Mature_310_residues
MQNLPGKTAFVTGGASGIGLGIAKALLGAGMNVTIADIRQDHLDSAVAELGGGERVLAVKLDVTNRDQFAKAADATEAKF
GKIHLLVNNAGVAVVGPTELATFADWDWVMGVNVNGTINGIVTILPRILAHGEGGHIVCTASMSALVPVAGTTIYSAGKA
AVTAMMECMRPELEGRGVICSAFCPGAVQSNIADAAKTRPAELADTGYAEADKRRAAGGNFMHLYQTKEQVGERVLEGIL
NDELYILTHAEFLTGVEERGLATTAAVQTHLPENPEYKETFAALFRNPAITDEIARQNKLKETRKAGVEA

Specific function: Catalyzes the C alpha dehydrogenation of arylglycerol- beta-aryl ether (C alpha alcohol type) (compound IV) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=31.3432835820896, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI19923817, Length=197, Percent_Identity=29.9492385786802, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI4503817, Length=206, Percent_Identity=28.6407766990291, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI40548397, Length=226, Percent_Identity=27.4336283185841, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI214010158, Length=226, Percent_Identity=27.4336283185841, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI214010156, Length=226, Percent_Identity=27.4336283185841, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI22758144, Length=226, Percent_Identity=27.4336283185841, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=29.2079207920792, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI224922801, Length=182, Percent_Identity=30.2197802197802, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI7705855, Length=198, Percent_Identity=28.2828282828283, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4758504, Length=196, Percent_Identity=29.0816326530612, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI22507405, Length=253, Percent_Identity=29.6442687747036, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI66933014, Length=190, Percent_Identity=30.5263157894737, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI83715985, Length=175, Percent_Identity=30.2857142857143, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI5031737, Length=195, Percent_Identity=29.2307692307692, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI32483357, Length=192, Percent_Identity=27.6041666666667, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI109715829, Length=222, Percent_Identity=27.9279279279279, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=28.643216080402, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI150247226, Length=245, Percent_Identity=26.9387755102041, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4504503, Length=193, Percent_Identity=29.5336787564767, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI10190704, Length=190, Percent_Identity=30.5263157894737, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082100, Length=195, Percent_Identity=32.3076923076923, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=30.5555555555556, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786812, Length=191, Percent_Identity=30.3664921465969, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789208, Length=208, Percent_Identity=29.3269230769231, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786701, Length=189, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788459, Length=198, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082160, Length=198, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790717, Length=195, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787905, Length=198, Percent_Identity=30.8080808080808, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=194, Percent_Identity=30.4123711340206, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=211, Percent_Identity=29.3838862559242, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=192, Percent_Identity=31.25, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=218, Percent_Identity=29.3577981651376, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=193, Percent_Identity=28.4974093264249, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=233, Percent_Identity=27.8969957081545, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=233, Percent_Identity=27.8969957081545, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=183, Percent_Identity=28.9617486338798, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=202, Percent_Identity=27.2277227722772, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=212, Percent_Identity=25.9433962264151, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=206, Percent_Identity=26.6990291262136, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=196, Percent_Identity=30.6122448979592, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24665243, Length=195, Percent_Identity=32.8205128205128, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21356301, Length=208, Percent_Identity=32.6923076923077, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221331218, Length=195, Percent_Identity=32.8205128205128, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24665247, Length=196, Percent_Identity=32.6530612244898, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=30.5263157894737, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221331216, Length=196, Percent_Identity=32.6530612244898, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21358495, Length=247, Percent_Identity=25.9109311740891, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571526, Length=196, Percent_Identity=31.1224489795918, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355631, Length=216, Percent_Identity=28.2407407407407, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=29.4605809128631, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17737361, Length=198, Percent_Identity=32.8282828282828, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281364494, Length=230, Percent_Identity=28.695652173913, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24663911, Length=205, Percent_Identity=31.7073170731707, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355319, Length=198, Percent_Identity=30.3030303030303, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI23397609, Length=194, Percent_Identity=32.4742268041237, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281364892, Length=176, Percent_Identity=30.1136363636364, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24648944, Length=204, Percent_Identity=28.4313725490196, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24641232, Length=203, Percent_Identity=32.0197044334975, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32598; Mature: 32598

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLPGKTAFVTGGASGIGLGIAKALLGAGMNVTIADIRQDHLDSAVAELGGGERVLAVK
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEEE
LDVTNRDQFAKAADATEAKFGKIHLLVNNAGVAVVGPTELATFADWDWVMGVNVNGTING
EECCCCHHHHHHHCCCCCCCCEEEEEEECCCEEEECCHHHHHCCCCCEEEEEECCCHHHH
IVTILPRILAHGEGGHIVCTASMSALVPVAGTTIYSAGKAAVTAMMECMRPELEGRGVIC
HHHHHHHHHHCCCCCEEEEEECCHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCCCEEE
SAFCPGAVQSNIADAAKTRPAELADTGYAEADKRRAAGGNFMHLYQTKEQVGERVLEGIL
ECCCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHH
NDELYILTHAEFLTGVEERGLATTAAVQTHLPENPEYKETFAALFRNPAITDEIARQNKL
CCCEEEEEEHHHHHCHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
KETRKAGVEA
HHHHHCCCCC
>Mature Secondary Structure
MQNLPGKTAFVTGGASGIGLGIAKALLGAGMNVTIADIRQDHLDSAVAELGGGERVLAVK
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEEE
LDVTNRDQFAKAADATEAKFGKIHLLVNNAGVAVVGPTELATFADWDWVMGVNVNGTING
EECCCCHHHHHHHCCCCCCCCEEEEEEECCCEEEECCHHHHHCCCCCEEEEEECCCHHHH
IVTILPRILAHGEGGHIVCTASMSALVPVAGTTIYSAGKAAVTAMMECMRPELEGRGVIC
HHHHHHHHHHCCCCCEEEEEECCHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCCCEEE
SAFCPGAVQSNIADAAKTRPAELADTGYAEADKRRAAGGNFMHLYQTKEQVGERVLEGIL
ECCCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHH
NDELYILTHAEFLTGVEERGLATTAAVQTHLPENPEYKETFAALFRNPAITDEIARQNKL
CCCEEEEEEHHHHHCHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHH
KETRKAGVEA
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1744051; 8495726; 7764263 [H]