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The map label for this gene is aprE [H]

Identifier: 87198270

GI number: 87198270

Start: 253632

End: 254972

Strand: Direct

Name: aprE [H]

Synonym: Saro_0245

Alternate gene names: 87198270

Gene position: 253632-254972 (Clockwise)

Preceding gene: 87198269

Following gene: 87198271

Centisome position: 7.12

GC content: 67.19

Gene sequence:

>1341_bases
ATGAGCTTGCCAGCAGTCATGGGCGGAACGAACCTGCCGGTCCCTTGGGACACCGACGCTCCCGCGCCCGAGTCCGCCAC
CAACCTGCGCCGCCTCGCCGCGATCGTGGGCGGGCTGTTCGTTGTCCTGTTCGCGATGGCGCTGGTCGTGCCGATCGGCG
GCGCGGTGATCGGGAACGGCCAGGTCGGCGTCCAGTCGCGGGTCAAGCGGATTGCCCATCCTACCGGCGGCGTGATTGCC
GAAATCGCCGTGACCAACGGCGAACACGTGAAGCAAGGCCAGTTGCTGATGCGGCTGGACGACCGTGTCACCGGTGCGGA
TGCAACGTATTCGAGCCTGACCGTCGAGCAGTTGCTGGCCCAGCGCGCGCGCCTTGAGGCAGAGCGTCTCGGCCTCGGCT
CGGTCACATTCCCGCCCGAGCTGCTCAATGCCGGAACGCCCAGCGCGGCGAAGGCCATGGCCGACGAAGCGCACCTGTTC
CGCATGCGCAGTGTCGAAACGGCGCAGGTCCGAGCACAACTCGGCGCGCGCGTGAACCAGTACCAGCAGGAGATCCGCGG
CATCGAGGCGCAGATCGCGTCGCTGCGCAAGCAGCGCACCCTGATCGAGCCCGAGCGCCAGAGCGTAAAGGACCTGTGGG
ACAAGCAGCTCGTCACGATCAACCGGTTGAACCAGCTCGAACGCTCCGCCGTCGATCTCGACGGGTCGGTCGGCGCGCTC
AATGCGCAGATTGCGCAGGCCCGCGCGCGCATCACCGAGGCGCAGGAACAGTCGATCCAGGTAAGCCAGCAGCGCCGCGT
AGATGCCGGCGTGGAACTGGCCCAGGTCAACACCGCGCTCAACCAGCAGCGCCTTCGCAGCGTCGCGGCCAACGACCAGC
AGGACCGCAGCGAGATCCGCGCGCCCTATTCCGGCACGGTCGAGAAGATCGCCTTCGCCGCGATCGGCGACGTGGTCCGT
CCGGCCGAGCCGATCATGGAAATAGTGCCCGATCGCGACGTGATGGTGGTCGAGGCGGCCATCGGCCCGGCGGACATCGA
CCAGGTGGCGAAGGGGCAGGTGGCGCGCGTGCGCTTTTCCGCCTTCAACCGCGCGGCCACGCCGGAAATCGCCGGCAAGG
TGCTCTACGTCGCAACCGACCGGACAGAGAATCCCGAATCCCGCGCATCGTTCTACATGGTCCGGATCGCGGTGGACCAG
GCTGCCATCGCCCGCGAGAAGCTGGACTTGCGCAGCGGGATGCCCGCCGAAGTCTATATCGAGACCGGCAGTCGGTCGCT
CCTTTCCTATTTCACCAAGCCGCTGCGCGACCAGTTCTCGCGCGCGTTCCGGGACAATTGA

Upstream 100 bases:

>100_bases
CCAACCCCGGCGAGCCGAAGGACGGCCAGACCGTTGCCGCCCGGACAGGCCCGGCCAAGGTCGGTGCCAGCAAGACCGGT
TCCGAAGGGGAGGTTGCGCA

Downstream 100 bases:

>100_bases
GCATGAGGCCAAAGGCGAACGGCGGCGTGGCATGGCTGGCTCTGCTTCTGGCGGAAACAGCCACAGGCACCGTCGTATCC
ACAGTCGCACCCACCGTCGC

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSLPAVMGGTNLPVPWDTDAPAPESATNLRRLAAIVGGLFVVLFAMALVVPIGGAVIGNGQVGVQSRVKRIAHPTGGVIA
EIAVTNGEHVKQGQLLMRLDDRVTGADATYSSLTVEQLLAQRARLEAERLGLGSVTFPPELLNAGTPSAAKAMADEAHLF
RMRSVETAQVRAQLGARVNQYQQEIRGIEAQIASLRKQRTLIEPERQSVKDLWDKQLVTINRLNQLERSAVDLDGSVGAL
NAQIAQARARITEAQEQSIQVSQQRRVDAGVELAQVNTALNQQRLRSVAANDQQDRSEIRAPYSGTVEKIAFAAIGDVVR
PAEPIMEIVPDRDVMVVEAAIGPADIDQVAKGQVARVRFSAFNRAATPEIAGKVLYVATDRTENPESRASFYMVRIAVDQ
AAIAREKLDLRSGMPAEVYIETGSRSLLSYFTKPLRDQFSRAFRDN

Sequences:

>Translated_446_residues
MSLPAVMGGTNLPVPWDTDAPAPESATNLRRLAAIVGGLFVVLFAMALVVPIGGAVIGNGQVGVQSRVKRIAHPTGGVIA
EIAVTNGEHVKQGQLLMRLDDRVTGADATYSSLTVEQLLAQRARLEAERLGLGSVTFPPELLNAGTPSAAKAMADEAHLF
RMRSVETAQVRAQLGARVNQYQQEIRGIEAQIASLRKQRTLIEPERQSVKDLWDKQLVTINRLNQLERSAVDLDGSVGAL
NAQIAQARARITEAQEQSIQVSQQRRVDAGVELAQVNTALNQQRLRSVAANDQQDRSEIRAPYSGTVEKIAFAAIGDVVR
PAEPIMEIVPDRDVMVVEAAIGPADIDQVAKGQVARVRFSAFNRAATPEIAGKVLYVATDRTENPESRASFYMVRIAVDQ
AAIAREKLDLRSGMPAEVYIETGSRSLLSYFTKPLRDQFSRAFRDN
>Mature_445_residues
SLPAVMGGTNLPVPWDTDAPAPESATNLRRLAAIVGGLFVVLFAMALVVPIGGAVIGNGQVGVQSRVKRIAHPTGGVIAE
IAVTNGEHVKQGQLLMRLDDRVTGADATYSSLTVEQLLAQRARLEAERLGLGSVTFPPELLNAGTPSAAKAMADEAHLFR
MRSVETAQVRAQLGARVNQYQQEIRGIEAQIASLRKQRTLIEPERQSVKDLWDKQLVTINRLNQLERSAVDLDGSVGALN
AQIAQARARITEAQEQSIQVSQQRRVDAGVELAQVNTALNQQRLRSVAANDQQDRSEIRAPYSGTVEKIAFAAIGDVVRP
AEPIMEIVPDRDVMVVEAAIGPADIDQVAKGQVARVRFSAFNRAATPEIAGKVLYVATDRTENPESRASFYMVRIAVDQA
AIAREKLDLRSGMPAEVYIETGSRSLLSYFTKPLRDQFSRAFRDN

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 48445; Mature: 48314

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPAVMGGTNLPVPWDTDAPAPESATNLRRLAAIVGGLFVVLFAMALVVPIGGAVIGNG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
QVGVQSRVKRIAHPTGGVIAEIAVTNGEHVKQGQLLMRLDDRVTGADATYSSLTVEQLLA
CCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHEEECCCCCCCCCHHHHHHHHHHHH
QRARLEAERLGLGSVTFPPELLNAGTPSAAKAMADEAHLFRMRSVETAQVRAQLGARVNQ
HHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
YQQEIRGIEAQIASLRKQRTLIEPERQSVKDLWDKQLVTINRLNQLERSAVDLDGSVGAL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
NAQIAQARARITEAQEQSIQVSQQRRVDAGVELAQVNTALNQQRLRSVAANDQQDRSEIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
APYSGTVEKIAFAAIGDVVRPAEPIMEIVPDRDVMVVEAAIGPADIDQVAKGQVARVRFS
CCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHCCHHHHHHHH
AFNRAATPEIAGKVLYVATDRTENPESRASFYMVRIAVDQAAIAREKLDLRSGMPAEVYI
HHCCCCCHHHCCEEEEEEECCCCCCCHHHHEEEEEEEHHHHHHHHHHHHHHCCCCCEEEE
ETGSRSLLSYFTKPLRDQFSRAFRDN
ECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLPAVMGGTNLPVPWDTDAPAPESATNLRRLAAIVGGLFVVLFAMALVVPIGGAVIGNG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
QVGVQSRVKRIAHPTGGVIAEIAVTNGEHVKQGQLLMRLDDRVTGADATYSSLTVEQLLA
CCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHEEECCCCCCCCCHHHHHHHHHHHH
QRARLEAERLGLGSVTFPPELLNAGTPSAAKAMADEAHLFRMRSVETAQVRAQLGARVNQ
HHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
YQQEIRGIEAQIASLRKQRTLIEPERQSVKDLWDKQLVTINRLNQLERSAVDLDGSVGAL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
NAQIAQARARITEAQEQSIQVSQQRRVDAGVELAQVNTALNQQRLRSVAANDQQDRSEIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
APYSGTVEKIAFAAIGDVVRPAEPIMEIVPDRDVMVVEAAIGPADIDQVAKGQVARVRFS
CCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHCCHHHHHHHH
AFNRAATPEIAGKVLYVATDRTENPESRASFYMVRIAVDQAAIAREKLDLRSGMPAEVYI
HHCCCCCHHHCCEEEEEEECCCCCCCHHHHEEEEEEEHHHHHHHHHHHHHHCCCCCEEEE
ETGSRSLLSYFTKPLRDQFSRAFRDN
ECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]