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The map label for this gene is pnuC [H]

Identifier: 87198038

GI number: 87198038

Start: 9493

End: 10056

Strand: Direct

Name: pnuC [H]

Synonym: Saro_0012

Alternate gene names: 87198038

Gene position: 9493-10056 (Clockwise)

Preceding gene: 87198037

Following gene: 87198039

Centisome position: 0.27

GC content: 64.72

Gene sequence:

>564_bases
GTGAACCCGGTCGAACTTGCGGCGAGCTTGCTCGGCCTTGCCAACATCGCGCTGCTGGTGCGGCGTTCGGTATGGAACTT
CCCTTTCGCGCTGGGCTCAGTCTCCTGCACCGGCGTGGTGCTGTGGGAAGCTCGGCTCTATGCCGAAACCGGCCTGCAAG
CGTTCTTCTTCGCGACCAACCTGTGGGGCTGGTGGCTCTGGGCCCAGGCACGCGGTGCAGAGGAAAGCGCGGTGCCAGTC
CGATGGATGAGCATGCCGGAGCGGATGACCTGGTCAGGAGCGACAACAGTGCTGAGTCTTTCGCTCGGCTGGCTGCTCCA
CCGTTTCACCAACGCCGCGCTGCCTTTTGCCGACTCCGCCGTGACCGGCGCCAGCATTGCCGCGCAGATTCTGCTCTCGC
TGCGCAGGGTGGAGAACTGGGTCCTTTGGGTGGCGATCGACGTGGTCGGCATCGGGCTCTACCTGGCTCGTGGACTTCCG
CTCCTCGCGACACTGTACGCGGTGTTCCTCGTGCTGTCGGTGCTGGGCTTGCGCCAATGGACCAAGGCCGCACGATCATG
CTGA

Upstream 100 bases:

>100_bases
GCCGAGCATGCCTCGGTCATCAAGCGTCCGGTCGTCGAGCATCCGGGCGGGCTCCTTGTCGGCTTCAAGGAAGCGGAGTG
GGCGGCGGCGCTCGCCTGAC

Downstream 100 bases:

>100_bases
GAGTGTGTTTCCACGGGGCCGAAAGTACCGGAAAATCGGTGCTGGCTGCACGGCTGCACCACCGCTTCGGCTGGCCATGG
GTTCCCGAATACGGCCGCGA

Product: nicotinamide mononucleotide transporter

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNPVELAASLLGLANIALLVRRSVWNFPFALGSVSCTGVVLWEARLYAETGLQAFFFATNLWGWWLWAQARGAEESAVPV
RWMSMPERMTWSGATTVLSLSLGWLLHRFTNAALPFADSAVTGASIAAQILLSLRRVENWVLWVAIDVVGIGLYLARGLP
LLATLYAVFLVLSVLGLRQWTKAARSC

Sequences:

>Translated_187_residues
MNPVELAASLLGLANIALLVRRSVWNFPFALGSVSCTGVVLWEARLYAETGLQAFFFATNLWGWWLWAQARGAEESAVPV
RWMSMPERMTWSGATTVLSLSLGWLLHRFTNAALPFADSAVTGASIAAQILLSLRRVENWVLWVAIDVVGIGLYLARGLP
LLATLYAVFLVLSVLGLRQWTKAARSC
>Mature_187_residues
MNPVELAASLLGLANIALLVRRSVWNFPFALGSVSCTGVVLWEARLYAETGLQAFFFATNLWGWWLWAQARGAEESAVPV
RWMSMPERMTWSGATTVLSLSLGWLLHRFTNAALPFADSAVTGASIAAQILLSLRRVENWVLWVAIDVVGIGLYLARGLP
LLATLYAVFLVLSVLGLRQWTKAARSC

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=207, Percent_Identity=28.5024154589372, Blast_Score=93, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 20566; Mature: 20566

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVELAASLLGLANIALLVRRSVWNFPFALGSVSCTGVVLWEARLYAETGLQAFFFATN
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEHHHHHHHHHCHHHHHHHHH
LWGWWLWAQARGAEESAVPVRWMSMPERMTWSGATTVLSLSLGWLLHRFTNAALPFADSA
HHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
VTGASIAAQILLSLRRVENWVLWVAIDVVGIGLYLARGLPLLATLYAVFLVLSVLGLRQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TKAARSC
HHHHHCC
>Mature Secondary Structure
MNPVELAASLLGLANIALLVRRSVWNFPFALGSVSCTGVVLWEARLYAETGLQAFFFATN
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEHHHHHHHHHCHHHHHHHHH
LWGWWLWAQARGAEESAVPVRWMSMPERMTWSGATTVLSLSLGWLLHRFTNAALPFADSA
HHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
VTGASIAAQILLSLRRVENWVLWVAIDVVGIGLYLARGLPLLATLYAVFLVLSVLGLRQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TKAARSC
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 2841129; 2198247 [H]