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The map label for this gene is dnaA

Identifier: 87198027

GI number: 87198027

Start: 24

End: 1520

Strand: Direct

Name: dnaA

Synonym: Saro_0001

Alternate gene names: 87198027

Gene position: 24-1520 (Clockwise)

Preceding gene: NA

Following gene: 87198028

Centisome position: 0.0

GC content: 65.93

Gene sequence:

>1497_bases
ATGGAAGAATTCGCAGGGGGAGCCTTGGCCCGTGGCGTGAACAGCGCTGCCAATTCAGGCGGCGAGCGCGCACAGGCAGG
CAAGAAGGGACGTGAAAGCAACATGATCGAAGACCAGGAAGCGCTGGATCTGGCTGCCGACTGGGCCGACATCAGCCAGG
GCCTCAAGAAGGACCTGGGGCCGCAACTCCACGCCCAGTGGATCAAGCCGATCCAGCTCGGCTCGTTCTGCAAGGAAACC
GGCACGCTCGACCTGTTCCTGCCGACCGAATTCTCCGCCAACTGGGTTGCAGATCGCTTTGCCGATCGCCTCAGCCTGGC
GTGGAAGATTGCCCGCTCGGAAGTGCGGCAGGTGCGCATCACCGTTCACCCACGCCGTCGTTCGATGCCGGAACTGCGCG
TCGGCGCGGCGCCGACCGCCCCGAGCCGCGCCGCGACGCTCGCCGCCACGTCGCCCGTGATGGTCGATTCGGCGCTTTCG
GGCCTCGACCCCTCGCTGACCTTCGCGGAATTCGTCTCGGGTTCGGCCAACGTGCTGGCGGTCAACGCCGCGCAGCGCAT
GGCAGCCATCGAGGCGCCGCAGTTCTCGCCGCTCTACCTCAAGGGCTCGACCGGCCAGGGCAAGACCCACCTGCTTCACG
CCATCGGCCACGCCTTTGCCGCCAACAAGCCGGGCGCCCGGATCTTCTACTGCTCGGCCGAACGGTTCATGATCGAATTC
GTCCAGGCCATGCGCTCGAACGAGATGATCGAGTTCAAGTCTCGGCTGCGCGGATTCGACATGCTGCTGGTCGACGACAT
CCAGTTCATCATCGGCAAGGCTTCGACGCAGGAGGAATTCCTCCACACGATCGACGCGCTGATGAGCGCGGGCAAGCGAC
TCGTCGTTGCCGCCGACCGTGCGCCCCAGGCGCTCGACGGGGTCGAACAGCGCCTGCTCTCGCGCCTGTCGATGGGCCTC
GTTGCCGATATCCAGCCAGCCGACATCGAACTGCGCCGCAAAATCCTCGAACACCGCCTCGCCCGCTTCGGCAACACGCA
GGTGCCTTCGGACGTGGTCGAGTTCCTCGCCCGCACGATCAACCGCAACGTGCGCGAACTGGTGGGCGGGCTCAACAAGC
TGATCGCCTATGCCCAGCTCACCGGCCAGCCGGTCTCGCTGCAACTGGCGGAAGAACAGTTGACCGATATCCTCTCGGCC
AACCGCCGCCGCATCACCATCGACGAGATCCAGCGCACGGTCTGCCAGTTCTACCGCGTCGACCGCACCGAAATGGCCAG
CAAGCGCCGCGCCCGCGCGGTCGTTCGTCCGCGCCAGGTGGCGATGTACCTTGCCAAGGTGCTGACGCCGCGCTCTTATC
CGGAGATCGGCCGCAAGTTCGGCGGTCGCGACCACTCCACCGTGATCCACGCGGTCCGTCTGATCGAGGAACTGCGCGCC
CGCGATGCCGACATGGACGGCGACGTGCGCACGCTCCTGCGCCAGCTTGAGGACTGA

Upstream 100 bases:

>100_bases
ATTTGGTCTGCCGTGCAATCCGCGCGGCCGGGCGGGGTAAACTTGTGTCTTGTCGCCGGGGGGCGCACAGGCACGATAGT
CGGGGCATCGACGTGTGAAG

Downstream 100 bases:

>100_bases
ACAGGCTTTCCCTGGCCGGTCCATCGGTTTTCCCGGGGTTTTGCACAGACATGGCCCGGAGGCGCGCAATGCTCGCCTTC
GGGCCGTTTTGCATCTAGAT

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MEEFAGGALARGVNSAANSGGERAQAGKKGRESNMIEDQEALDLAADWADISQGLKKDLGPQLHAQWIKPIQLGSFCKET
GTLDLFLPTEFSANWVADRFADRLSLAWKIARSEVRQVRITVHPRRRSMPELRVGAAPTAPSRAATLAATSPVMVDSALS
GLDPSLTFAEFVSGSANVLAVNAAQRMAAIEAPQFSPLYLKGSTGQGKTHLLHAIGHAFAANKPGARIFYCSAERFMIEF
VQAMRSNEMIEFKSRLRGFDMLLVDDIQFIIGKASTQEEFLHTIDALMSAGKRLVVAADRAPQALDGVEQRLLSRLSMGL
VADIQPADIELRRKILEHRLARFGNTQVPSDVVEFLARTINRNVRELVGGLNKLIAYAQLTGQPVSLQLAEEQLTDILSA
NRRRITIDEIQRTVCQFYRVDRTEMASKRRARAVVRPRQVAMYLAKVLTPRSYPEIGRKFGGRDHSTVIHAVRLIEELRA
RDADMDGDVRTLLRQLED

Sequences:

>Translated_498_residues
MEEFAGGALARGVNSAANSGGERAQAGKKGRESNMIEDQEALDLAADWADISQGLKKDLGPQLHAQWIKPIQLGSFCKET
GTLDLFLPTEFSANWVADRFADRLSLAWKIARSEVRQVRITVHPRRRSMPELRVGAAPTAPSRAATLAATSPVMVDSALS
GLDPSLTFAEFVSGSANVLAVNAAQRMAAIEAPQFSPLYLKGSTGQGKTHLLHAIGHAFAANKPGARIFYCSAERFMIEF
VQAMRSNEMIEFKSRLRGFDMLLVDDIQFIIGKASTQEEFLHTIDALMSAGKRLVVAADRAPQALDGVEQRLLSRLSMGL
VADIQPADIELRRKILEHRLARFGNTQVPSDVVEFLARTINRNVRELVGGLNKLIAYAQLTGQPVSLQLAEEQLTDILSA
NRRRITIDEIQRTVCQFYRVDRTEMASKRRARAVVRPRQVAMYLAKVLTPRSYPEIGRKFGGRDHSTVIHAVRLIEELRA
RDADMDGDVRTLLRQLED
>Mature_498_residues
MEEFAGGALARGVNSAANSGGERAQAGKKGRESNMIEDQEALDLAADWADISQGLKKDLGPQLHAQWIKPIQLGSFCKET
GTLDLFLPTEFSANWVADRFADRLSLAWKIARSEVRQVRITVHPRRRSMPELRVGAAPTAPSRAATLAATSPVMVDSALS
GLDPSLTFAEFVSGSANVLAVNAAQRMAAIEAPQFSPLYLKGSTGQGKTHLLHAIGHAFAANKPGARIFYCSAERFMIEF
VQAMRSNEMIEFKSRLRGFDMLLVDDIQFIIGKASTQEEFLHTIDALMSAGKRLVVAADRAPQALDGVEQRLLSRLSMGL
VADIQPADIELRRKILEHRLARFGNTQVPSDVVEFLARTINRNVRELVGGLNKLIAYAQLTGQPVSLQLAEEQLTDILSA
NRRRITIDEIQRTVCQFYRVDRTEMASKRRARAVVRPRQVAMYLAKVLTPRSYPEIGRKFGGRDHSTVIHAVRLIEELRA
RDADMDGDVRTLLRQLED

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=467, Percent_Identity=38.5438972162741, Blast_Score=318, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 55123; Mature: 55123

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEFAGGALARGVNSAANSGGERAQAGKKGRESNMIEDQEALDLAADWADISQGLKKDLG
CCCCCCCHHHHCCCHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PQLHAQWIKPIQLGSFCKETGTLDLFLPTEFSANWVADRFADRLSLAWKIARSEVRQVRI
HHHHHHHHCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEE
TVHPRRRSMPELRVGAAPTAPSRAATLAATSPVMVDSALSGLDPSLTFAEFVSGSANVLA
EECCCCCCCCCCCCCCCCCCCCCCEEHHCCCCHHHHHHHHCCCCCHHHHHHHCCCCCEEE
VNAAQRMAAIEAPQFSPLYLKGSTGQGKTHLLHAIGHAFAANKPGARIFYCSAERFMIEF
EEHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHH
VQAMRSNEMIEFKSRLRGFDMLLVDDIQFIIGKASTQEEFLHTIDALMSAGKRLVVAADR
HHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEECC
APQALDGVEQRLLSRLSMGLVADIQPADIELRRKILEHRLARFGNTQVPSDVVEFLARTI
CCHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
NRNVRELVGGLNKLIAYAQLTGQPVSLQLAEEQLTDILSANRRRITIDEIQRTVCQFYRV
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHC
DRTEMASKRRARAVVRPRQVAMYLAKVLTPRSYPEIGRKFGGRDHSTVIHAVRLIEELRA
CHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHH
RDADMDGDVRTLLRQLED
CCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MEEFAGGALARGVNSAANSGGERAQAGKKGRESNMIEDQEALDLAADWADISQGLKKDLG
CCCCCCCHHHHCCCHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PQLHAQWIKPIQLGSFCKETGTLDLFLPTEFSANWVADRFADRLSLAWKIARSEVRQVRI
HHHHHHHHCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEE
TVHPRRRSMPELRVGAAPTAPSRAATLAATSPVMVDSALSGLDPSLTFAEFVSGSANVLA
EECCCCCCCCCCCCCCCCCCCCCCEEHHCCCCHHHHHHHHCCCCCHHHHHHHCCCCCEEE
VNAAQRMAAIEAPQFSPLYLKGSTGQGKTHLLHAIGHAFAANKPGARIFYCSAERFMIEF
EEHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHH
VQAMRSNEMIEFKSRLRGFDMLLVDDIQFIIGKASTQEEFLHTIDALMSAGKRLVVAADR
HHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEECC
APQALDGVEQRLLSRLSMGLVADIQPADIELRRKILEHRLARFGNTQVPSDVVEFLARTI
CCHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
NRNVRELVGGLNKLIAYAQLTGQPVSLQLAEEQLTDILSANRRRITIDEIQRTVCQFYRV
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHC
DRTEMASKRRARAVVRPRQVAMYLAKVLTPRSYPEIGRKFGGRDHSTVIHAVRLIEELRA
CHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHH
RDADMDGDVRTLLRQLED
CCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA