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The map label for this gene is kdpA [H]

Identifier: 86751743

GI number: 86751743

Start: 5251050

End: 5252753

Strand: Direct

Name: kdpA [H]

Synonym: RPB_4645

Alternate gene names: 86751743

Gene position: 5251050-5252753 (Clockwise)

Preceding gene: 86751742

Following gene: 86751744

Centisome position: 98.49

GC content: 65.96

Gene sequence:

>1704_bases
ATGACACTGATTGGATGGACCCAGATCGCGCTGTTCTGCGCGATCATCGTCGCGCTGACGCCGTTGCTCGGCGCCTATCT
CACCCACGTTTTCGACGGCCAGACCACGCCGCTGTCGTTCGTGCTCAGGCCGGTCGAAACCGGTCTGTACCGCCTCGCCG
GCGTCGACCCGCAGCGCGAGCAGCACTGGCTGACCTATACGTTGGCGATGCTGCTGTTTCACGCCGCCGGCTTCGTGCTG
CTGTATTTGCTGCTGCGGCTGCAGGCGGTGCTGCCACTGAACCCGGCGGAGCAAGGCGCGGTGGCACCGGATCTCGCGCT
CAACACGGCGGTCTCGTTCCTCACCAACACCAACTGGCAGAACTACGGCGGCGAGAGCACGCTGTCGTATCTCACCCAGA
TGTTCGGGCTGACGGTGCAGAACTTCCTGTCCGCCGCCACCGGCATCGTGCTGGCGGTGGCGCTGATCCGCGGCTTCGCC
CGCGCCTCGGCGAAGACCATCGGCAATTTCTGGGTCGACGTCACCCGCTGCACGCTCTACGTGCTGCTGCCGATCTGCAT
CGTCTTCACCCTCTTTCTGGTCTGGCAGGGTGTGCCGCAGACGCTGGGGCCGTCTATCGACGCGACCACGCTCGAAGGCG
GCAGGCAGACGATCGCGCTCGGGCCGGTGGGCTCCCAGGTCGCGATCAAGATGCTCGGCACCAATGGCGGCGGCTTCTTC
AACGCCAACGCCGCGCATCCGCTCGAGAACCCGACCGCGCTGTCGAACTTCCTGCAGATGCTGTCGATCTTCGCGCTCGG
CGCGGCACTCACCAATGTGTTCGGCCGGATGGTCGGCGATCAGCGCCAGGGCTGGGCGATCCTGGCCGCGATGGGCGTTC
TGTTCATCGCCGGCGTCGCGGTCTGCTACTGGGCCGAAGCCAACGGCACGCAGATCCTGCAGGCGGCCGGTCTTGCCGGT
GGAAACATGGAAGGCAAGGAGGTCCGCTTCGGCATCGCCGCCTCGGCGCTGTTCGCGGCGATCACCACCGCGGCCTCGTG
CGGCGCCGTCAACGCGATGCACGACAGCTTCACCGCGCTCGGCGGCATGATCCCGATCATCAACATGGAGCTCGGCGAAA
TCGTGATCGGCGGCGTCGGCGCCGGACTCTACGGCATGCTGCTGTTCGTGATCATCACGATCTTTCTTGCCGGACTGATG
GTCGGCCGCACGCCGGAATATGTCGGCAAGAAGATCGAGGCGCGCGAGGTCAAGATGGCGATGCTCGCGATCCTGATCCT
GCCGCTGTTGATGCTCGGCTTCACCGCGATCGCCGTGGTGTATCCGCCGGCGGTGGCGTCGATGGCCAATGCCGGGCCGC
ACGGCTTCTCGGAAGTGCTCTACGCCTTCACCTCGCAGGCCGCCAACAACGGCTCGGCGTTCGGCGGCCTGACCGGCAAC
ACGCCGTTCTACAATCTCGCCGGCTCGATCGCGATGTTCCTCGGGCGGTTCTGGATGATCATCCCGGCGATGGCCATCGC
CGGCTCGCTGGCGGGCAAGAAATCGGTCGCCGCCACGGCAGGCACCTTCCCGACCAGCGGCCCGTTGTTCGTCGGGCTAC
TCGTCGGCGTCATTCTGATCGTCGGTGGCCTCACCTTCTTTCCGGCGCTCGCCGTCGGCCCCATCGTCGAGCATCTCGCG
ATGCTGAACGGCACCGCCTACTAA

Upstream 100 bases:

>100_bases
GATGTCGTTCGACTATGTTCTCGCCGCATCGGTCAGCGCCGCGCTGCTGATCTATCTCGTCACCGCGCTGTTGCGCCCCG
AACGCTTCTAGGGGGCTGCG

Downstream 100 bases:

>100_bases
TCCGGAGACACATCCATGCAAGCGAAACTCCGCAAACGGACCGCCGCCTCGGCCATGCTCGATCCGGCGATCCTGCTCCC
CGCGATCGGTCACGCCTTCG

Product: potassium-transporting ATPase subunit A

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MTLIGWTQIALFCAIIVALTPLLGAYLTHVFDGQTTPLSFVLRPVETGLYRLAGVDPQREQHWLTYTLAMLLFHAAGFVL
LYLLLRLQAVLPLNPAEQGAVAPDLALNTAVSFLTNTNWQNYGGESTLSYLTQMFGLTVQNFLSAATGIVLAVALIRGFA
RASAKTIGNFWVDVTRCTLYVLLPICIVFTLFLVWQGVPQTLGPSIDATTLEGGRQTIALGPVGSQVAIKMLGTNGGGFF
NANAAHPLENPTALSNFLQMLSIFALGAALTNVFGRMVGDQRQGWAILAAMGVLFIAGVAVCYWAEANGTQILQAAGLAG
GNMEGKEVRFGIAASALFAAITTAASCGAVNAMHDSFTALGGMIPIINMELGEIVIGGVGAGLYGMLLFVIITIFLAGLM
VGRTPEYVGKKIEAREVKMAMLAILILPLLMLGFTAIAVVYPPAVASMANAGPHGFSEVLYAFTSQAANNGSAFGGLTGN
TPFYNLAGSIAMFLGRFWMIIPAMAIAGSLAGKKSVAATAGTFPTSGPLFVGLLVGVILIVGGLTFFPALAVGPIVEHLA
MLNGTAY

Sequences:

>Translated_567_residues
MTLIGWTQIALFCAIIVALTPLLGAYLTHVFDGQTTPLSFVLRPVETGLYRLAGVDPQREQHWLTYTLAMLLFHAAGFVL
LYLLLRLQAVLPLNPAEQGAVAPDLALNTAVSFLTNTNWQNYGGESTLSYLTQMFGLTVQNFLSAATGIVLAVALIRGFA
RASAKTIGNFWVDVTRCTLYVLLPICIVFTLFLVWQGVPQTLGPSIDATTLEGGRQTIALGPVGSQVAIKMLGTNGGGFF
NANAAHPLENPTALSNFLQMLSIFALGAALTNVFGRMVGDQRQGWAILAAMGVLFIAGVAVCYWAEANGTQILQAAGLAG
GNMEGKEVRFGIAASALFAAITTAASCGAVNAMHDSFTALGGMIPIINMELGEIVIGGVGAGLYGMLLFVIITIFLAGLM
VGRTPEYVGKKIEAREVKMAMLAILILPLLMLGFTAIAVVYPPAVASMANAGPHGFSEVLYAFTSQAANNGSAFGGLTGN
TPFYNLAGSIAMFLGRFWMIIPAMAIAGSLAGKKSVAATAGTFPTSGPLFVGLLVGVILIVGGLTFFPALAVGPIVEHLA
MLNGTAY
>Mature_566_residues
TLIGWTQIALFCAIIVALTPLLGAYLTHVFDGQTTPLSFVLRPVETGLYRLAGVDPQREQHWLTYTLAMLLFHAAGFVLL
YLLLRLQAVLPLNPAEQGAVAPDLALNTAVSFLTNTNWQNYGGESTLSYLTQMFGLTVQNFLSAATGIVLAVALIRGFAR
ASAKTIGNFWVDVTRCTLYVLLPICIVFTLFLVWQGVPQTLGPSIDATTLEGGRQTIALGPVGSQVAIKMLGTNGGGFFN
ANAAHPLENPTALSNFLQMLSIFALGAALTNVFGRMVGDQRQGWAILAAMGVLFIAGVAVCYWAEANGTQILQAAGLAGG
NMEGKEVRFGIAASALFAAITTAASCGAVNAMHDSFTALGGMIPIINMELGEIVIGGVGAGLYGMLLFVIITIFLAGLMV
GRTPEYVGKKIEAREVKMAMLAILILPLLMLGFTAIAVVYPPAVASMANAGPHGFSEVLYAFTSQAANNGSAFGGLTGNT
PFYNLAGSIAMFLGRFWMIIPAMAIAGSLAGKKSVAATAGTFPTSGPLFVGLLVGVILIVGGLTFFPALAVGPIVEHLAM
LNGTAY

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions [H]

COG id: COG2060

COG function: function code P; K+-transporting ATPase, A chain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdpA family [H]

Homologues:

Organism=Escherichia coli, GI1786915, Length=557, Percent_Identity=55.2962298025135, Blast_Score=587, Evalue=1e-169,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004623 [H]

Pfam domain/function: PF03814 KdpA [H]

EC number: =3.6.3.12 [H]

Molecular weight: Translated: 59316; Mature: 59185

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLIGWTQIALFCAIIVALTPLLGAYLTHVFDGQTTPLSFVLRPVETGLYRLAGVDPQRE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
QHWLTYTLAMLLFHAAGFVLLYLLLRLQAVLPLNPAEQGAVAPDLALNTAVSFLTNTNWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
NYGGESTLSYLTQMFGLTVQNFLSAATGIVLAVALIRGFARASAKTIGNFWVDVTRCTLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLPICIVFTLFLVWQGVPQTLGPSIDATTLEGGRQTIALGPVGSQVAIKMLGTNGGGFF
HHHHHHHHHHHHHHHCCCCHHHCCCCCCEECCCCCEEEEECCCCCCEEEEEEECCCCCEE
NANAAHPLENPTALSNFLQMLSIFALGAALTNVFGRMVGDQRQGWAILAAMGVLFIAGVA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VCYWAEANGTQILQAAGLAGGNMEGKEVRFGIAASALFAAITTAASCGAVNAMHDSFTAL
HHHEECCCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GGMIPIINMELGEIVIGGVGAGLYGMLLFVIITIFLAGLMVGRTPEYVGKKIEAREVKMA
CCCHHEEECCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
MLAILILPLLMLGFTAIAVVYPPAVASMANAGPHGFSEVLYAFTSQAANNGSAFGGLTGN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
TPFYNLAGSIAMFLGRFWMIIPAMAIAGSLAGKKSVAATAGTFPTSGPLFVGLLVGVILI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHH
VGGLTFFPALAVGPIVEHLAMLNGTAY
HHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLIGWTQIALFCAIIVALTPLLGAYLTHVFDGQTTPLSFVLRPVETGLYRLAGVDPQRE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
QHWLTYTLAMLLFHAAGFVLLYLLLRLQAVLPLNPAEQGAVAPDLALNTAVSFLTNTNWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
NYGGESTLSYLTQMFGLTVQNFLSAATGIVLAVALIRGFARASAKTIGNFWVDVTRCTLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLPICIVFTLFLVWQGVPQTLGPSIDATTLEGGRQTIALGPVGSQVAIKMLGTNGGGFF
HHHHHHHHHHHHHHHCCCCHHHCCCCCCEECCCCCEEEEECCCCCCEEEEEEECCCCCEE
NANAAHPLENPTALSNFLQMLSIFALGAALTNVFGRMVGDQRQGWAILAAMGVLFIAGVA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VCYWAEANGTQILQAAGLAGGNMEGKEVRFGIAASALFAAITTAASCGAVNAMHDSFTAL
HHHEECCCCHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GGMIPIINMELGEIVIGGVGAGLYGMLLFVIITIFLAGLMVGRTPEYVGKKIEAREVKMA
CCCHHEEECCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
MLAILILPLLMLGFTAIAVVYPPAVASMANAGPHGFSEVLYAFTSQAANNGSAFGGLTGN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
TPFYNLAGSIAMFLGRFWMIIPAMAIAGSLAGKKSVAATAGTFPTSGPLFVGLLVGVILI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHH
VGGLTFFPALAVGPIVEHLAMLNGTAY
HHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]