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The map label for this gene is degU [H]

Identifier: 86751540

GI number: 86751540

Start: 5029307

End: 5029825

Strand: Direct

Name: degU [H]

Synonym: RPB_4442

Alternate gene names: 86751540

Gene position: 5029307-5029825 (Clockwise)

Preceding gene: 86751539

Following gene: 86751547

Centisome position: 94.33

GC content: 64.93

Gene sequence:

>519_bases
ATGGATGGTCGAACAACACCCCGCCTGCGCGTCTTCCTGGCCGACGACCACCCGCTCGTGCTCCGCGGCATGAAGATGCT
GATCGGGAACGACGCCGGCCTGGAACTCGTCGGCGACGCCTCCGACGGACCGAGCGCACTCCAGCGCGCGATCGAATTGA
AGCCGGATGTCGCGGTCCTCGACCTGTGGATGCCGGGTCTCAGAGGGCTGGATGTCGCCCGCCAGTTTCTGTCGATCTGC
CCGACATCCCGCGTGCTGGTGCTGACGGTCCACGAAGACGCGGCCTATCTGCGCAAGGTCCTGCAATGTGGCGTGACCGG
CTACATTCTCAAACGCTCGGCGACCGACGAGCTCGCTCGCGGCATCCACGCGGTGGCGGCCGGAGGTCTTTATCTGGATC
CGCACTTCCTGGCCGACAGGACCGACGGGGAGTTGATTCTCCGGCAGTCGGCCCGGCGGGTGGGACTCAACCTCTTCATC
GAGACCGTCGACAATCTGAAGCGGAACAGCATCCACTAG

Upstream 100 bases:

>100_bases
CCTCATCCAGTGATTGGACTACGGCGATGCCGCTAGGCGCATCCTTCGTAGCCGTGCAAATCTATCTTGCCATTTCTTCG
CTCCGTCGGGACCATGAACC

Downstream 100 bases:

>100_bases
CGCGAGTCGCGGCGTGGTCGGCACATCGCCCTTCGGCAGGCCCGGCGAGCCGCTGTCCTGTCATTGTGGAAGCGTTCGCA
TGGCGACGCTAACGGCCTTC

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MDGRTTPRLRVFLADDHPLVLRGMKMLIGNDAGLELVGDASDGPSALQRAIELKPDVAVLDLWMPGLRGLDVARQFLSIC
PTSRVLVLTVHEDAAYLRKVLQCGVTGYILKRSATDELARGIHAVAAGGLYLDPHFLADRTDGELILRQSARRVGLNLFI
ETVDNLKRNSIH

Sequences:

>Translated_172_residues
MDGRTTPRLRVFLADDHPLVLRGMKMLIGNDAGLELVGDASDGPSALQRAIELKPDVAVLDLWMPGLRGLDVARQFLSIC
PTSRVLVLTVHEDAAYLRKVLQCGVTGYILKRSATDELARGIHAVAAGGLYLDPHFLADRTDGELILRQSARRVGLNLFI
ETVDNLKRNSIH
>Mature_172_residues
MDGRTTPRLRVFLADDHPLVLRGMKMLIGNDAGLELVGDASDGPSALQRAIELKPDVAVLDLWMPGLRGLDVARQFLSIC
PTSRVLVLTVHEDAAYLRKVLQCGVTGYILKRSATDELARGIHAVAAGGLYLDPHFLADRTDGELILRQSARRVGLNLFI
ETVDNLKRNSIH

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=124, Percent_Identity=33.0645161290323, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788521, Length=126, Percent_Identity=37.3015873015873, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI1790102, Length=126, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=1e-13,
Organism=Escherichia coli, GI1788712, Length=130, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=3e-13,
Organism=Escherichia coli, GI1787473, Length=122, Percent_Identity=33.6065573770492, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788546, Length=127, Percent_Identity=27.5590551181102, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 18862; Mature: 18862

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGRTTPRLRVFLADDHPLVLRGMKMLIGNDAGLELVGDASDGPSALQRAIELKPDVAVL
CCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEE
DLWMPGLRGLDVARQFLSICPTSRVLVLTVHEDAAYLRKVLQCGVTGYILKRSATDELAR
EECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCHHEEEECCCHHHHHH
GIHAVAAGGLYLDPHFLADRTDGELILRQSARRVGLNLFIETVDNLKRNSIH
HHHHHHCCCEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDGRTTPRLRVFLADDHPLVLRGMKMLIGNDAGLELVGDASDGPSALQRAIELKPDVAVL
CCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEE
DLWMPGLRGLDVARQFLSICPTSRVLVLTVHEDAAYLRKVLQCGVTGYILKRSATDELAR
EECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCHHEEEECCCHHHHHH
GIHAVAAGGLYLDPHFLADRTDGELILRQSARRVGLNLFIETVDNLKRNSIH
HHHHHHCCCEEECCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]