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The map label for this gene is cutS [H]

Identifier: 86751514

GI number: 86751514

Start: 4999997

End: 5000464

Strand: Reverse

Name: cutS [H]

Synonym: RPB_4413

Alternate gene names: 86751514

Gene position: 5000464-4999997 (Counterclockwise)

Preceding gene: 86751515

Following gene: 86751513

Centisome position: 93.79

GC content: 64.53

Gene sequence:

>468_bases
ATGGCCGATATCGCTTCGCTCGACATTTCCTTCACGCTCAACGGCGCGCCGCAGACTCGGTCGGTGGCGCCGTTCGAACT
GCTGATCGACTTCCTGCGCGACGATCTTGGACTGAAAGGCACCAAGCGCTCCTGCGACGTGCAGGTGTGCGGCGCCTGCA
CCGTGCTGGTCGACGGTCTCCCGGTGAGTAGCTGCACGTCGCTCGCCGCCGACATCGACGGCAGATCGGTGGTGACGATC
GAAGGGCTGGCGCAGCGCGGCGAACTCAGCCCGGTGCAGCAGGCGTTCGTCGACCACGCAGCGATGCAGTGCGGATTCTG
CACGCCCGGCATGGTGCTGGCGACCACGGCTTTGCTGGAGCACCATCCGCATCCGACCGAGCAGGAGATCCGGCATTATC
TGCGCGGCAACATCTGCCGCTGCACCGGCTACATCAAGATCCTCGAAGCGGTGAAGAGCCTTGTCTGA

Upstream 100 bases:

>100_bases
GACGACATCTACGGCAGCGCCGACTACAAGCGGCATCTCGCCGCCGTGTTCATCGGACGCGCAGTGCTGGACAGCGCCGG
CGTGGCAGGAGGGCGCTGAC

Downstream 100 bases:

>100_bases
ACTCTCGATCTCCAGCGACGGCAGAGACGAACCGGCCGTGTTTCGCGACAAGGTCGCGGCCGGCGAAGCCGGTGGCGCCG
ACACGATCTGGATCGCCAAC

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MADIASLDISFTLNGAPQTRSVAPFELLIDFLRDDLGLKGTKRSCDVQVCGACTVLVDGLPVSSCTSLAADIDGRSVVTI
EGLAQRGELSPVQQAFVDHAAMQCGFCTPGMVLATTALLEHHPHPTEQEIRHYLRGNICRCTGYIKILEAVKSLV

Sequences:

>Translated_155_residues
MADIASLDISFTLNGAPQTRSVAPFELLIDFLRDDLGLKGTKRSCDVQVCGACTVLVDGLPVSSCTSLAADIDGRSVVTI
EGLAQRGELSPVQQAFVDHAAMQCGFCTPGMVLATTALLEHHPHPTEQEIRHYLRGNICRCTGYIKILEAVKSLV
>Mature_154_residues
ADIASLDISFTLNGAPQTRSVAPFELLIDFLRDDLGLKGTKRSCDVQVCGACTVLVDGLPVSSCTSLAADIDGRSVVTIE
GLAQRGELSPVQQAFVDHAAMQCGFCTPGMVLATTALLEHHPHPTEQEIRHYLRGNICRCTGYIKILEAVKSLV

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=156, Percent_Identity=35.8974358974359, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI71773480, Length=159, Percent_Identity=36.4779874213836, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1789232, Length=156, Percent_Identity=46.7948717948718, Blast_Score=129, Evalue=7e-32,
Organism=Escherichia coli, GI1786480, Length=161, Percent_Identity=37.888198757764, Blast_Score=115, Evalue=1e-27,
Organism=Escherichia coli, GI1789246, Length=145, Percent_Identity=33.1034482758621, Blast_Score=75, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17539860, Length=157, Percent_Identity=40.1273885350318, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=157, Percent_Identity=38.2165605095541, Blast_Score=117, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=168, Percent_Identity=38.0952380952381, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17737937, Length=156, Percent_Identity=38.4615384615385, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24647199, Length=157, Percent_Identity=36.9426751592357, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647201, Length=157, Percent_Identity=36.9426751592357, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24647195, Length=163, Percent_Identity=34.3558282208589, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24647197, Length=163, Percent_Identity=34.3558282208589, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24647193, Length=158, Percent_Identity=34.8101265822785, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 16613; Mature: 16482

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIASLDISFTLNGAPQTRSVAPFELLIDFLRDDLGLKGTKRSCDVQVCGACTVLVDGL
CCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEHHHEEEHCCCC
PVSSCTSLAADIDGRSVVTIEGLAQRGELSPVQQAFVDHAAMQCGFCTPGMVLATTALLE
CHHHHHHHHHCCCCCEEEEEECHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
HHPHPTEQEIRHYLRGNICRCTGYIKILEAVKSLV
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADIASLDISFTLNGAPQTRSVAPFELLIDFLRDDLGLKGTKRSCDVQVCGACTVLVDGL
CCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEHHHEEEHCCCC
PVSSCTSLAADIDGRSVVTIEGLAQRGELSPVQQAFVDHAAMQCGFCTPGMVLATTALLE
CHHHHHHHHHCCCCCEEEEEECHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
HHPHPTEQEIRHYLRGNICRCTGYIKILEAVKSLV
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]