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The map label for this gene is ccdA [H]

Identifier: 86751478

GI number: 86751478

Start: 4959149

End: 4959892

Strand: Reverse

Name: ccdA [H]

Synonym: RPB_4376

Alternate gene names: 86751478

Gene position: 4959892-4959149 (Counterclockwise)

Preceding gene: 86751482

Following gene: 86751477

Centisome position: 93.03

GC content: 67.47

Gene sequence:

>744_bases
GTGGCTTCTAGTATCTCTCTCATCGGCGCGTTCGGGGCGGGGGTGCTGTCGTTCCTGTCGCCCTGCGTGCTGCCATTGGT
GCCGCCGTATCTGTGCTTTCTGGCCGGCGTCAGCCTAGACCAGCTCTCCCGCGGTTCCGATCAGCCGGCGAAGGCGGTCG
ATTGGCGCGTGGTCGGGTCGGCGGTGGCCTTCGTGCTGGGATTTTCGACCGTGTTCGTCGCGCTCGGCGCGTCGGCCTCG
GTGGTCGGCAAGGTCGTCACCGAGTATTTCGAGACGCTGGCGATCGTCGCCGGGGTGGTCATCGTCATCCTCGGATTGCA
TTTTCTCGGCGTATTCCGGATCGGGCTGCTGTTTCGCGAGGCGCGCTTCCATAATGTCCGCCGCGGTGCCGGTTTTCTCG
GCGCCTATGTGGTCGGGCTCGCCTTCGCGTTCGGCTGGACGCCCTGTGTCGGCCCGGTGCTGGCGACGATCCTGCTGGTC
GCCGGCGTCGAGGGCGCGGCGGCGCGCGGCGCGGCGCTGCTCGGCGCCTATTCGCTGGGGATCGGGCTGCCGTTCCTGCT
GGCGGCGCTGTTCTCCGGCGGCTTCATCCGGCTGATGGCGCGGATGCGCGCCCATATGGCGACGATCGAGAAGCTGATGG
GCGCGGCGCTGGTCCTGACCGGGGTGCTGTTTCTGACCGGCGCGATGCCGAAAATTGCCGGATGGCTGCTGGAGACGTTT
CCGGCGTTCGGAACGATCGGATAG

Upstream 100 bases:

>100_bases
CGCCAGCATTGCGCAGAGCAGCATCGATTTCAGAAGCATTCGGGCCATGATATGATACATATAGACGAATTCGCATGTTT
ATTCCAGCGTCGAGAACGCC

Downstream 100 bases:

>100_bases
CGCGCGCCAAACAAGGAGGGCAGTGATGATCGACCGTCCAATGTCTCGCCGCCATGCGCTGGCCGCGCTCGGCGCCGGCG
CTCTCGGTTTGCGGATGATG

Product: cytochrome c biogenesis protein, transmembrane region

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MASSISLIGAFGAGVLSFLSPCVLPLVPPYLCFLAGVSLDQLSRGSDQPAKAVDWRVVGSAVAFVLGFSTVFVALGASAS
VVGKVVTEYFETLAIVAGVVIVILGLHFLGVFRIGLLFREARFHNVRRGAGFLGAYVVGLAFAFGWTPCVGPVLATILLV
AGVEGAAARGAALLGAYSLGIGLPFLLAALFSGGFIRLMARMRAHMATIEKLMGAALVLTGVLFLTGAMPKIAGWLLETF
PAFGTIG

Sequences:

>Translated_247_residues
MASSISLIGAFGAGVLSFLSPCVLPLVPPYLCFLAGVSLDQLSRGSDQPAKAVDWRVVGSAVAFVLGFSTVFVALGASAS
VVGKVVTEYFETLAIVAGVVIVILGLHFLGVFRIGLLFREARFHNVRRGAGFLGAYVVGLAFAFGWTPCVGPVLATILLV
AGVEGAAARGAALLGAYSLGIGLPFLLAALFSGGFIRLMARMRAHMATIEKLMGAALVLTGVLFLTGAMPKIAGWLLETF
PAFGTIG
>Mature_246_residues
ASSISLIGAFGAGVLSFLSPCVLPLVPPYLCFLAGVSLDQLSRGSDQPAKAVDWRVVGSAVAFVLGFSTVFVALGASASV
VGKVVTEYFETLAIVAGVVIVILGLHFLGVFRIGLLFREARFHNVRRGAGFLGAYVVGLAFAFGWTPCVGPVLATILLVA
GVEGAAARGAALLGAYSLGIGLPFLLAALFSGGFIRLMARMRAHMATIEKLMGAALVLTGVLFLTGAMPKIAGWLLETFP
AFGTIG

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 25465; Mature: 25334

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCC
>Mature Secondary Structure 
ASSISLIGAFGAGVLSFLSPCVLPLVPPYLCFLAGVSLDQLSRGSDQPAKAVDWRVVGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHH
AVAFVLGFSTVFVALGASASVVGKVVTEYFETLAIVAGVVIVILGLHFLGVFRIGLLFRE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARFHNVRRGAGFLGAYVVGLAFAFGWTPCVGPVLATILLVAGVEGAAARGAALLGAYSLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IGLPFLLAALFSGGFIRLMARMRAHMATIEKLMGAALVLTGVLFLTGAMPKIAGWLLETF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
PAFGTIG
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]