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The map label for this gene is hlyU [H]

Identifier: 86751404

GI number: 86751404

Start: 4889907

End: 4890227

Strand: Reverse

Name: hlyU [H]

Synonym: RPB_4302

Alternate gene names: 86751404

Gene position: 4890227-4889907 (Counterclockwise)

Preceding gene: 86751406

Following gene: 86751403

Centisome position: 91.72

GC content: 67.29

Gene sequence:

>321_bases
ATGGAAGCCGCTGCCGATCAGGCCAGCGACTTGTTGAAGGCGCTGGCGAACCGGCATCGGCTGTTGATCGTCTGCCAGCT
CATCGGCGGCGAACGCTCGGTCGGCGATCTCGCGGAGGTCCTGAGCCTGCGCGATTCGACCGTCTCCCAGCACCTCGCGC
TGTTGCGCAAGGACGGGCTGGTGGCGGCCCGCCGCGACGCCCAGACGATCTACTACTCGATCGCGAGCGAGCCGGCTCGC
GAACTCCTGACCACGCTGTACCGGCTGTACTGTCCGGCGCCGCCCGCGCGGAAGACGGCAAGCAAACCTGAGAAGGCATG
A

Upstream 100 bases:

>100_bases
TTCTGGGCGCGCGGGCCAAAATCCGTTCCGCCTGAATTCGTGATTGACGTTATATTCGAATAATCGTATATACGCAACTA
TGAAAATACAGGTCGAGCTC

Downstream 100 bases:

>100_bases
CGATGCGGATTCGCGACATGATCACGGCCGGTGCCTGCGCCGCCCTCCTGCTCGGCGCGGCGGCGACGCCCGCGGCGGCG
GCGACGCTCACGGTGGCGGA

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MEAAADQASDLLKALANRHRLLIVCQLIGGERSVGDLAEVLSLRDSTVSQHLALLRKDGLVAARRDAQTIYYSIASEPAR
ELLTTLYRLYCPAPPARKTASKPEKA

Sequences:

>Translated_106_residues
MEAAADQASDLLKALANRHRLLIVCQLIGGERSVGDLAEVLSLRDSTVSQHLALLRKDGLVAARRDAQTIYYSIASEPAR
ELLTTLYRLYCPAPPARKTASKPEKA
>Mature_106_residues
MEAAADQASDLLKALANRHRLLIVCQLIGGERSVGDLAEVLSLRDSTVSQHLALLRKDGLVAARRDAQTIYYSIASEPAR
ELLTTLYRLYCPAPPARKTASKPEKA

Specific function: Up-regulates the expression of the hemolysin gene, hlyA, and may promote expression of other virulence determinants in vivo. It may have both positive and negative regulator activities [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789021, Length=93, Percent_Identity=45.1612903225806, Blast_Score=82, Evalue=8e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11573; Mature: 11573

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAAADQASDLLKALANRHRLLIVCQLIGGERSVGDLAEVLSLRDSTVSQHLALLRKDGL
CCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
VAARRDAQTIYYSIASEPARELLTTLYRLYCPAPPARKTASKPEKA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEAAADQASDLLKALANRHRLLIVCQLIGGERSVGDLAEVLSLRDSTVSQHLALLRKDGL
CCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
VAARRDAQTIYYSIASEPARELLTTLYRLYCPAPPARKTASKPEKA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]