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The map label for this gene is nhaA2 [H]

Identifier: 86751401

GI number: 86751401

Start: 4884964

End: 4885632

Strand: Reverse

Name: nhaA2 [H]

Synonym: RPB_4299

Alternate gene names: 86751401

Gene position: 4885632-4884964 (Counterclockwise)

Preceding gene: 86751402

Following gene: 86751400

Centisome position: 91.63

GC content: 67.41

Gene sequence:

>669_bases
ATGGAATTGGAACCGATGATGATCACCCGACGATCGGCGCTGATGACCGCCCTGTCGCTCGCGCCGGCGCTGGCCGCGTC
GAAGGCGTGGGCCGCACCGGCCGCGCCGGCGTCGGACGACAACGTGCTGTCGACCGAGGCGGTGCTGCGCGATCCCGACA
TTCCGGTCGCCGGCAATCCCGACGGCGACATCACCATCGTCGAGTGGTCGGACTATCGCTGTCCCTACTGCAAGAAGGTT
GCGCCCGATCTCAGGCAGGTCGTGAAGGACGACGGCAAGGTTCGTCTGGTGCTGAAGGACTGGCCGATCTTCGGCGGCAT
CTCGGTCGATGCGGCCAAGATGGTGCTGGCGTCGAAATATCAGGGCAAGTTCTTCGAGGCGCACGACGCGCTGATCGGCA
GCACCGCGAAACTGACGTCGGCCGGCCTCACCGAATTGCTCGGCGCCGGCGGCGTCGACGTCGCGCGCGCGACCAGGGAC
CTCGACACCAACGGCGCCGCGATCGAGGCGATCCTGGCGCGGAACGATGCGCAGGCGAAGGCGTTCGGCTTCCAGGGCAC
GCCGGCCTTCATCGTCGGCCGGTTCCGGGTGCCGGGCGTGCTCGACGTCGCAATGTTCAAGCAGGCGATCAAGGACGCCC
GCGCGGCGGCGGCGCAGCAGAAGAAATAA

Upstream 100 bases:

>100_bases
ATCGTGCTGCGCGACAAATCGCCGACTCCGCCCGCCGGTCCGGTGGCAAAGGGATAGCATCGCCGGCCGATCCGGGGCAC
AAAGGTCCGATCCCGCCACG

Downstream 100 bases:

>100_bases
TCGTCGCCCGAGCGCGGAGCGAACAGGGGCGGCACCGCTGGTCGCGGCTCCGTTGGTTGATCTGAATCATCAAAGCGACG
CAGCCGTGCGCTAGGCTGCG

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MELEPMMITRRSALMTALSLAPALAASKAWAAPAAPASDDNVLSTEAVLRDPDIPVAGNPDGDITIVEWSDYRCPYCKKV
APDLRQVVKDDGKVRLVLKDWPIFGGISVDAAKMVLASKYQGKFFEAHDALIGSTAKLTSAGLTELLGAGGVDVARATRD
LDTNGAAIEAILARNDAQAKAFGFQGTPAFIVGRFRVPGVLDVAMFKQAIKDARAAAAQQKK

Sequences:

>Translated_222_residues
MELEPMMITRRSALMTALSLAPALAASKAWAAPAAPASDDNVLSTEAVLRDPDIPVAGNPDGDITIVEWSDYRCPYCKKV
APDLRQVVKDDGKVRLVLKDWPIFGGISVDAAKMVLASKYQGKFFEAHDALIGSTAKLTSAGLTELLGAGGVDVARATRD
LDTNGAAIEAILARNDAQAKAFGFQGTPAFIVGRFRVPGVLDVAMFKQAIKDARAAAAQQKK
>Mature_222_residues
MELEPMMITRRSALMTALSLAPALAASKAWAAPAAPASDDNVLSTEAVLRDPDIPVAGNPDGDITIVEWSDYRCPYCKKV
APDLRQVVKDDGKVRLVLKDWPIFGGISVDAAKMVLASKYQGKFFEAHDALIGSTAKLTSAGLTELLGAGGVDVARATRD
LDTNGAAIEAILARNDAQAKAFGFQGTPAFIVGRFRVPGVLDVAMFKQAIKDARAAAAQQKK

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 23498; Mature: 23498

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELEPMMITRRSALMTALSLAPALAASKAWAAPAAPASDDNVLSTEAVLRDPDIPVAGNP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHCCCCCCCCCCC
DGDITIVEWSDYRCPYCKKVAPDLRQVVKDDGKVRLVLKDWPIFGGISVDAAKMVLASKY
CCCEEEEEECCCCCCHHHHCCHHHHHHHHCCCCEEEEEECCCEECCCCHHHHHHHHHHHC
QGKFFEAHDALIGSTAKLTSAGLTELLGAGGVDVARATRDLDTNGAAIEAILARNDAQAK
CCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCHH
AFGFQGTPAFIVGRFRVPGVLDVAMFKQAIKDARAAAAQQKK
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELEPMMITRRSALMTALSLAPALAASKAWAAPAAPASDDNVLSTEAVLRDPDIPVAGNP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHCCCCCCCCCCC
DGDITIVEWSDYRCPYCKKVAPDLRQVVKDDGKVRLVLKDWPIFGGISVDAAKMVLASKY
CCCEEEEEECCCCCCHHHHCCHHHHHHHHCCCCEEEEEECCCEECCCCHHHHHHHHHHHC
QGKFFEAHDALIGSTAKLTSAGLTELLGAGGVDVARATRDLDTNGAAIEAILARNDAQAK
CCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCHH
AFGFQGTPAFIVGRFRVPGVLDVAMFKQAIKDARAAAAQQKK
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA