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The map label for this gene is mcp4 [H]

Identifier: 86751388

GI number: 86751388

Start: 4871323

End: 4873014

Strand: Direct

Name: mcp4 [H]

Synonym: RPB_4286

Alternate gene names: 86751388

Gene position: 4871323-4873014 (Clockwise)

Preceding gene: 86751387

Following gene: 86751389

Centisome position: 91.37

GC content: 66.31

Gene sequence:

>1692_bases
ATGCCGACCAACTTCTCCATTCGCGCCAAGATCAGTCTTGTCGTTGGGTTTCTGCTGATCACCATAATCGGCATGGGAAT
ACTGGCTGTCACAAAGACCCAGGCGATCAACACTGCAGCCGTCGATATCCAGAGCAACTGGCTGCCGCGCGTCCGCGCGC
TCGGCGATCTGCGCGCCGAAGTCGTCACCTATCGCGCCATCGTTCGCTTGCACCTGCTCTCCGAAACCGCGGACACCAAG
GCGGCGGTCGAAAATCGGATAGAGACCTCGGCGCAAGCGCTGCGGAAGTTTCGCGACGTCTACGAGAAGCTGATCGGCTC
CGCCGAAGAACGCGCGCTCTACAACGAGTGGAGTGAGCAATGGAATCTCTACGAAAGCCAGATTCCGCGGGTCGTCGCGC
TGTCGCGCGACAGCATCGGCCGCATCCCGCACGACGCCACCGCATTCAACGAGACCAAGGCCTATCCGATCTCGAAACAG
GCGGACGCCATTCTCGACCGGGACATCGCCCTCAACAACAAGGGCGCCGACGAAGCCGGCCGATTCGCGAACCAGGTCCA
TCAGTCGGCCTTGATGCAGTTGCTGATCATCATCGGCGCCGCCATCGTGCTCGGCGGCGGGCTGGCGATCTATCTGGTGC
GCGACGTGTCACGCGGCATCGATTCGATCGTGGCGCCGATGCAGGCGCTGGGTGCGGGCGACCTCGGCGCCAGCGTCCCG
CACCAGGGCGAGGCCACCGAAATCGGCAAGATGGCGGACTCGCTGCAGCTGTTCAAGGAGGCCTTGATCGCCAAGAAGGC
GGCCGACGAAGCCGCCATGAAGGACGCCGCCGAAAAGATCCAGCGCGGCCAGCGGGTCGACGAGATCACCCGCCACTTCG
AGCAGATGATCGGCGAGATCGTCGAGACGGTGGCGTCGGCCTCGACCGAACTGGAGGCCTCCGCCGGCACCCTCACCGCC
ACCGCCGACCGCGCCCAGCAGCTCACCACCTCGGTCGCCGCCGCCTCGGGCCAGGCCAGCGCCAATGTGCAATCGGTGGC
CTCGGCCACCGAGGAACTGACCTCCTCGGTGCAGGAGATCAGCCGCCAGGTCCAGGAATCGGCCCGGATCGCCGCCGAGG
CGGTCGATCAGGCGCGCGACACCAATCAGAGCGTCGGCCAGTTGACCCAGGCCGCGGCGCGGATCGGCGCCGTGGTGGAA
CTGATCAACACCATCGCCGGGCAGACCAACCTGCTGGCGCTGAACGCGACGATCGAAGCCGCCCGCGCCGGCGACGCCGG
CCGCGGCTTCGCCGTGGTCGCCTCCGAGGTCAAGGCGCTGGCCGAGCAGACCGCCAAGGCGACCGGCGAGATCAGCCAGC
AGATCTCCGGCATCCAATCCGCCACCCAGGAATCGGCCGGCGCCATCATGCAGATCGGCCAGACCATCGCCCGGATGTCG
GAAATCTCGTCGACGATCGCCGCGGCGGTGGAGGAGCAAGGCGCCGCCACCCACGAAATCGCCCGCAACGTGCAGCAGGC
GGCGCAGGGCACTCATCAGGTGTCGAGCAATATCGGCGACGTGCAGCGTGGCGCCAGCGAGACCGGCGCGGCGTCCTCGC
AGGTGCTGTCGGCGGCGCAATCGCTGTCGACCGAAAGCAACCGGCTGAAACTGGAAGTCGGCAATTTCCTCAGCAACGTC
CGAGCCGCCTGA

Upstream 100 bases:

>100_bases
AATGAGAGCGATCTACCGCCGCTGCGCCCCTCATCCTGACCAGCCCCTCGATCCCGAGTCGTTCGTCGGTGACCATCCAT
AGCGGTCAAGGATATCGACG

Downstream 100 bases:

>100_bases
TATCGCGAGCCGATCGATGGCCGCCCGGCCCAAAAACCGGGCGGCCATCCGCGCCAAATGTCGCACCGGGCCACCGCTGT
CATACCTGCGACAAACACCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MPTNFSIRAKISLVVGFLLITIIGMGILAVTKTQAINTAAVDIQSNWLPRVRALGDLRAEVVTYRAIVRLHLLSETADTK
AAVENRIETSAQALRKFRDVYEKLIGSAEERALYNEWSEQWNLYESQIPRVVALSRDSIGRIPHDATAFNETKAYPISKQ
ADAILDRDIALNNKGADEAGRFANQVHQSALMQLLIIIGAAIVLGGGLAIYLVRDVSRGIDSIVAPMQALGAGDLGASVP
HQGEATEIGKMADSLQLFKEALIAKKAADEAAMKDAAEKIQRGQRVDEITRHFEQMIGEIVETVASASTELEASAGTLTA
TADRAQQLTTSVAAASGQASANVQSVASATEELTSSVQEISRQVQESARIAAEAVDQARDTNQSVGQLTQAAARIGAVVE
LINTIAGQTNLLALNATIEAARAGDAGRGFAVVASEVKALAEQTAKATGEISQQISGIQSATQESAGAIMQIGQTIARMS
EISSTIAAAVEEQGAATHEIARNVQQAAQGTHQVSSNIGDVQRGASETGAASSQVLSAAQSLSTESNRLKLEVGNFLSNV
RAA

Sequences:

>Translated_563_residues
MPTNFSIRAKISLVVGFLLITIIGMGILAVTKTQAINTAAVDIQSNWLPRVRALGDLRAEVVTYRAIVRLHLLSETADTK
AAVENRIETSAQALRKFRDVYEKLIGSAEERALYNEWSEQWNLYESQIPRVVALSRDSIGRIPHDATAFNETKAYPISKQ
ADAILDRDIALNNKGADEAGRFANQVHQSALMQLLIIIGAAIVLGGGLAIYLVRDVSRGIDSIVAPMQALGAGDLGASVP
HQGEATEIGKMADSLQLFKEALIAKKAADEAAMKDAAEKIQRGQRVDEITRHFEQMIGEIVETVASASTELEASAGTLTA
TADRAQQLTTSVAAASGQASANVQSVASATEELTSSVQEISRQVQESARIAAEAVDQARDTNQSVGQLTQAAARIGAVVE
LINTIAGQTNLLALNATIEAARAGDAGRGFAVVASEVKALAEQTAKATGEISQQISGIQSATQESAGAIMQIGQTIARMS
EISSTIAAAVEEQGAATHEIARNVQQAAQGTHQVSSNIGDVQRGASETGAASSQVLSAAQSLSTESNRLKLEVGNFLSNV
RAA
>Mature_562_residues
PTNFSIRAKISLVVGFLLITIIGMGILAVTKTQAINTAAVDIQSNWLPRVRALGDLRAEVVTYRAIVRLHLLSETADTKA
AVENRIETSAQALRKFRDVYEKLIGSAEERALYNEWSEQWNLYESQIPRVVALSRDSIGRIPHDATAFNETKAYPISKQA
DAILDRDIALNNKGADEAGRFANQVHQSALMQLLIIIGAAIVLGGGLAIYLVRDVSRGIDSIVAPMQALGAGDLGASVPH
QGEATEIGKMADSLQLFKEALIAKKAADEAAMKDAAEKIQRGQRVDEITRHFEQMIGEIVETVASASTELEASAGTLTAT
ADRAQQLTTSVAAASGQASANVQSVASATEELTSSVQEISRQVQESARIAAEAVDQARDTNQSVGQLTQAAARIGAVVEL
INTIAGQTNLLALNATIEAARAGDAGRGFAVVASEVKALAEQTAKATGEISQQISGIQSATQESAGAIMQIGQTIARMSE
ISSTIAAAVEEQGAATHEIARNVQQAAQGTHQVSSNIGDVQRGASETGAASSQVLSAAQSLSTESNRLKLEVGNFLSNVR
AA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=488, Percent_Identity=25.2049180327869, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI2367378, Length=334, Percent_Identity=27.5449101796407, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788194, Length=385, Percent_Identity=29.3506493506493, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789453, Length=296, Percent_Identity=29.0540540540541, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788195, Length=241, Percent_Identity=31.9502074688797, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59270; Mature: 59139

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50885 HAMP ; PS00061 ADH_SHORT ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTNFSIRAKISLVVGFLLITIIGMGILAVTKTQAINTAAVDIQSNWLPRVRALGDLRAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHH
VVTYRAIVRLHLLSETADTKAAVENRIETSAQALRKFRDVYEKLIGSAEERALYNEWSEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
WNLYESQIPRVVALSRDSIGRIPHDATAFNETKAYPISKQADAILDRDIALNNKGADEAG
HCHHHHHCCCEEEECCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHH
RFANQVHQSALMQLLIIIGAAIVLGGGLAIYLVRDVSRGIDSIVAPMQALGAGDLGASVP
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
HQGEATEIGKMADSLQLFKEALIAKKAADEAAMKDAAEKIQRGQRVDEITRHFEQMIGEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VETVASASTELEASAGTLTATADRAQQLTTSVAAASGQASANVQSVASATEELTSSVQEI
HHHHHHCCCHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SRQVQESARIAAEAVDQARDTNQSVGQLTQAAARIGAVVELINTIAGQTNLLALNATIEA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHH
ARAGDAGRGFAVVASEVKALAEQTAKATGEISQQISGIQSATQESAGAIMQIGQTIARMS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EISSTIAAAVEEQGAATHEIARNVQQAAQGTHQVSSNIGDVQRGASETGAASSQVLSAAQ
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHH
SLSTESNRLKLEVGNFLSNVRAA
HHCCCCCEEEEEHHHHHHHHCCC
>Mature Secondary Structure 
PTNFSIRAKISLVVGFLLITIIGMGILAVTKTQAINTAAVDIQSNWLPRVRALGDLRAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHH
VVTYRAIVRLHLLSETADTKAAVENRIETSAQALRKFRDVYEKLIGSAEERALYNEWSEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
WNLYESQIPRVVALSRDSIGRIPHDATAFNETKAYPISKQADAILDRDIALNNKGADEAG
HCHHHHHCCCEEEECCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHH
RFANQVHQSALMQLLIIIGAAIVLGGGLAIYLVRDVSRGIDSIVAPMQALGAGDLGASVP
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
HQGEATEIGKMADSLQLFKEALIAKKAADEAAMKDAAEKIQRGQRVDEITRHFEQMIGEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VETVASASTELEASAGTLTATADRAQQLTTSVAAASGQASANVQSVASATEELTSSVQEI
HHHHHHCCCHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SRQVQESARIAAEAVDQARDTNQSVGQLTQAAARIGAVVELINTIAGQTNLLALNATIEA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHH
ARAGDAGRGFAVVASEVKALAEQTAKATGEISQQISGIQSATQESAGAIMQIGQTIARMS
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EISSTIAAAVEEQGAATHEIARNVQQAAQGTHQVSSNIGDVQRGASETGAASSQVLSAAQ
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHH
SLSTESNRLKLEVGNFLSNVRAA
HHCCCCCEEEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]