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The map label for this gene is mcp4 [H]

Identifier: 86751377

GI number: 86751377

Start: 4857657

End: 4859408

Strand: Direct

Name: mcp4 [H]

Synonym: RPB_4274

Alternate gene names: 86751377

Gene position: 4857657-4859408 (Clockwise)

Preceding gene: 86751366

Following gene: 86751378

Centisome position: 91.11

GC content: 69.75

Gene sequence:

>1752_bases
ATGGCGTTCGGCCTCTTTCGAAAGCAGCAGCCGGAAACGGCCGCGCCTGACGTCGCGCGGGCCCCGGCGCCCGAGCCGAC
GCCTCTGCCCGCTGCCGAGACCGATTCGGCGTCCGAAATCCTCGAACTGCTCGAACTCGAGCTCGGCTCGCTGATCCGCC
AGCTCGAACGCGCCGCCCAGTCGGTCACCACCGGGGTGCAATCCACCACCACCACGCTGCACACCATTCGCGAGCGCACC
GATGCGCTGACCGGGCGCACCAGCGCCGCGCAGGCGACGGCGTCGTCGTTCTCGCAGGCCGCCGACAAATTCACCGATTC
GGCGCAGGGCATCGGCGCCCAGGTGCGGCAGGCGGCGCAGCTCGCCGACGACGCCAGCGCGGCGGCGGACGAGGCCACCG
CCAATGTCGAGCGGCTGCGCGAATCCTCCGGGGCGATCGGCAATGTCGTCAATCTGATCGCGCAGATCGCCCGCCAGACC
ACGCTGCTGGCGCTGAATTCGACGATCGAGGCAGCCCGCGCCGGCGCCGCCGGCCGCGGCTTCGCGGTGGTCGCCACCGA
GGTCAAGGCGCTCGCGGTGCAGACCCAGGAGGCGACCGAGGAGATCAAGCGCAAGATCGACGCGCTGCAGCGCGACGCCT
CCAGCTCGGCCGACGCCGTTCACCGCATCACCAGCGCGATCGCGGCGATCCGGCCGGTGTTCGAGAACGTCAACGGCGCG
GTCGCCGAGCAGAACACCACCACCGGCGACATCGCCGGCAACGCCGCGACCGCCAGCAGCTTCATCGTCTCGGTCGGCGA
CAGCGCCGCCGAGATCGAGAGCGCCACCCGCGAAGCCGAACAGCACGGCGGCGAAGTCGCCAAGGCCGGCCAGGCGGTGA
CGATGTATGCCGAGAAGCTGCGCACGCGCACCGCGGTGCTGCTCAAACAGGGCGACCGCGAACAGGCGCGCAAGCGCGAG
AAGCTGCCGTGCCATCTGTCGATCGCGATCGACACGCCGCGCGGCAAAGTCGAGGCGCCAGTTTACGAGATCTCGCTGGA
CGGCCTGCTGATCGCCGGGCCCGGCGCCGCGGCGCTGCCGCTGCGGCAGCCGCTCGCGGCCGAGCTGCAGGATATCGGCG
CCTGCAGGATCCGCATCGACGCGCAAACCGGCGCCGGCGCACAGGCGAGCTTCGTCGCGCCGAGCACCACACTGCGTGAA
CTGATCGAAGACCGGCTGTGGGCGATCCGCGACGAGAACACCGAGTTCGTCACCCGCGCGCTCGAAGCCGGCGCCGAGCT
GCATCGGATTTTCGAACGCGGCATCGCCACCGGCGCGATCACGCTGGAGGAGATGTTCGACGACACTTACGTCGAGATCG
CCGGCACCAACCCGACGCAATATCGCACCCGGATCCTGACCTGGGCCGATCAGGCGCTGCCGCCGTTCCAGGAGGCGTTC
CTCGCCAAGGACAAGCGGATGGCGTTCTGCGCGATGATCGACCGCAACGGCTATCTGCCGGTGCACAATAGGATCTACTC
GCAGCCGCAGCGCCCGGGCGACACGACTTTCAACACCGCCAACAGCCGCAACCGCCGGATCTTCAACGATCCGGCCGGGC
TCGCCGCCGGCCGCAACACCCGCCCGTTCCTGATCCAGAGCTACGCCCGCGACATGGGCGGCGGCAACATGGTGATGATG
CGCGAGATCGACGTCCCGGTGAAAGTCCGCGGCCGGCACTGGGGCGGCTTCCGGACGGCGTACAGGCTGTAG

Upstream 100 bases:

>100_bases
ATCCGCACCGGAACCGGATTTCCGCATCGAGAAATTTAACCGTAATTTCACGCAGGCCTGCGAGAGTAGCAGGTAAATTT
CGCGTCCTGCGGGAGGATTC

Downstream 100 bases:

>100_bases
GGCGTCTGGGCGATGACCGAACTCTCCCGAACCGCGCAGAACGAGGTCACCAAGCTGACGGCCAGTTTCGTCAGCAATCT
GGGCGTGGGCCTCATCGCCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MAFGLFRKQQPETAAPDVARAPAPEPTPLPAAETDSASEILELLELELGSLIRQLERAAQSVTTGVQSTTTTLHTIRERT
DALTGRTSAAQATASSFSQAADKFTDSAQGIGAQVRQAAQLADDASAAADEATANVERLRESSGAIGNVVNLIAQIARQT
TLLALNSTIEAARAGAAGRGFAVVATEVKALAVQTQEATEEIKRKIDALQRDASSSADAVHRITSAIAAIRPVFENVNGA
VAEQNTTTGDIAGNAATASSFIVSVGDSAAEIESATREAEQHGGEVAKAGQAVTMYAEKLRTRTAVLLKQGDREQARKRE
KLPCHLSIAIDTPRGKVEAPVYEISLDGLLIAGPGAAALPLRQPLAAELQDIGACRIRIDAQTGAGAQASFVAPSTTLRE
LIEDRLWAIRDENTEFVTRALEAGAELHRIFERGIATGAITLEEMFDDTYVEIAGTNPTQYRTRILTWADQALPPFQEAF
LAKDKRMAFCAMIDRNGYLPVHNRIYSQPQRPGDTTFNTANSRNRRIFNDPAGLAAGRNTRPFLIQSYARDMGGGNMVMM
REIDVPVKVRGRHWGGFRTAYRL

Sequences:

>Translated_583_residues
MAFGLFRKQQPETAAPDVARAPAPEPTPLPAAETDSASEILELLELELGSLIRQLERAAQSVTTGVQSTTTTLHTIRERT
DALTGRTSAAQATASSFSQAADKFTDSAQGIGAQVRQAAQLADDASAAADEATANVERLRESSGAIGNVVNLIAQIARQT
TLLALNSTIEAARAGAAGRGFAVVATEVKALAVQTQEATEEIKRKIDALQRDASSSADAVHRITSAIAAIRPVFENVNGA
VAEQNTTTGDIAGNAATASSFIVSVGDSAAEIESATREAEQHGGEVAKAGQAVTMYAEKLRTRTAVLLKQGDREQARKRE
KLPCHLSIAIDTPRGKVEAPVYEISLDGLLIAGPGAAALPLRQPLAAELQDIGACRIRIDAQTGAGAQASFVAPSTTLRE
LIEDRLWAIRDENTEFVTRALEAGAELHRIFERGIATGAITLEEMFDDTYVEIAGTNPTQYRTRILTWADQALPPFQEAF
LAKDKRMAFCAMIDRNGYLPVHNRIYSQPQRPGDTTFNTANSRNRRIFNDPAGLAAGRNTRPFLIQSYARDMGGGNMVMM
REIDVPVKVRGRHWGGFRTAYRL
>Mature_582_residues
AFGLFRKQQPETAAPDVARAPAPEPTPLPAAETDSASEILELLELELGSLIRQLERAAQSVTTGVQSTTTTLHTIRERTD
ALTGRTSAAQATASSFSQAADKFTDSAQGIGAQVRQAAQLADDASAAADEATANVERLRESSGAIGNVVNLIAQIARQTT
LLALNSTIEAARAGAAGRGFAVVATEVKALAVQTQEATEEIKRKIDALQRDASSSADAVHRITSAIAAIRPVFENVNGAV
AEQNTTTGDIAGNAATASSFIVSVGDSAAEIESATREAEQHGGEVAKAGQAVTMYAEKLRTRTAVLLKQGDREQARKREK
LPCHLSIAIDTPRGKVEAPVYEISLDGLLIAGPGAAALPLRQPLAAELQDIGACRIRIDAQTGAGAQASFVAPSTTLREL
IEDRLWAIRDENTEFVTRALEAGAELHRIFERGIATGAITLEEMFDDTYVEIAGTNPTQYRTRILTWADQALPPFQEAFL
AKDKRMAFCAMIDRNGYLPVHNRIYSQPQRPGDTTFNTANSRNRRIFNDPAGLAAGRNTRPFLIQSYARDMGGGNMVMMR
EIDVPVKVRGRHWGGFRTAYRL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=238, Percent_Identity=34.453781512605, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI2367378, Length=260, Percent_Identity=28.8461538461538, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788194, Length=199, Percent_Identity=31.1557788944724, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787690, Length=227, Percent_Identity=30.3964757709251, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1789453, Length=216, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62502; Mature: 62371

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFGLFRKQQPETAAPDVARAPAPEPTPLPAAETDSASEILELLELELGSLIRQLERAAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SVTTGVQSTTTTLHTIRERTDALTGRTSAAQATASSFSQAADKFTDSAQGIGAQVRQAAQ
HHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LADDASAAADEATANVERLRESSGAIGNVVNLIAQIARQTTLLALNSTIEAARAGAAGRG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCC
FAVVATEVKALAVQTQEATEEIKRKIDALQRDASSSADAVHRITSAIAAIRPVFENVNGA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
VAEQNTTTGDIAGNAATASSFIVSVGDSAAEIESATREAEQHGGEVAKAGQAVTMYAEKL
EECCCCCCCCCCCCCHHHHHHEEECCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
RTRTAVLLKQGDREQARKREKLPCHLSIAIDTPRGKVEAPVYEISLDGLLIAGPGAAALP
HHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEEECCEEEECCCCCCCC
LRQPLAAELQDIGACRIRIDAQTGAGAQASFVAPSTTLRELIEDRLWAIRDENTEFVTRA
CCCHHHHHHHHCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHH
LEAGAELHRIFERGIATGAITLEEMFDDTYVEIAGTNPTQYRTRILTWADQALPPFQEAF
HHHHHHHHHHHHHCCCCCEEEHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHH
LAKDKRMAFCAMIDRNGYLPVHNRIYSQPQRPGDTTFNTANSRNRRIFNDPAGLAAGRNT
HHCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
RPFLIQSYARDMGGGNMVMMREIDVPVKVRGRHWGGFRTAYRL
CCHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCHHHHCC
>Mature Secondary Structure 
AFGLFRKQQPETAAPDVARAPAPEPTPLPAAETDSASEILELLELELGSLIRQLERAAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SVTTGVQSTTTTLHTIRERTDALTGRTSAAQATASSFSQAADKFTDSAQGIGAQVRQAAQ
HHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LADDASAAADEATANVERLRESSGAIGNVVNLIAQIARQTTLLALNSTIEAARAGAAGRG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCC
FAVVATEVKALAVQTQEATEEIKRKIDALQRDASSSADAVHRITSAIAAIRPVFENVNGA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
VAEQNTTTGDIAGNAATASSFIVSVGDSAAEIESATREAEQHGGEVAKAGQAVTMYAEKL
EECCCCCCCCCCCCCHHHHHHEEECCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHH
RTRTAVLLKQGDREQARKREKLPCHLSIAIDTPRGKVEAPVYEISLDGLLIAGPGAAALP
HHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEEECCEEEECCCCCCCC
LRQPLAAELQDIGACRIRIDAQTGAGAQASFVAPSTTLRELIEDRLWAIRDENTEFVTRA
CCCHHHHHHHHCCEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHH
LEAGAELHRIFERGIATGAITLEEMFDDTYVEIAGTNPTQYRTRILTWADQALPPFQEAF
HHHHHHHHHHHHHCCCCCEEEHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHH
LAKDKRMAFCAMIDRNGYLPVHNRIYSQPQRPGDTTFNTANSRNRRIFNDPAGLAAGRNT
HHCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
RPFLIQSYARDMGGGNMVMMREIDVPVKVRGRHWGGFRTAYRL
CCHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]