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The map label for this gene is ndh [H]

Identifier: 86751370

GI number: 86751370

Start: 4851117

End: 4852475

Strand: Reverse

Name: ndh [H]

Synonym: RPB_4267

Alternate gene names: 86751370

Gene position: 4852475-4851117 (Counterclockwise)

Preceding gene: 86751371

Following gene: 86751369

Centisome position: 91.01

GC content: 67.03

Gene sequence:

>1359_bases
ATGCTACACGGAACGCACCGGCGGTCCGCTACGTTGGGATGCATCATGACCGAGACAACACCCCACAGGATCGTCATCGT
CGGCGGCGGCGCCGGCGGGCTCGAGCTCGCCACCGCGCTCGGCGACAAATACGGCAAGTCCGATAATGTGCGCGTCACGC
TGGTCGATCGCAGCCGCACCCACATCTGGAAGCCGCTGCTGCACGCGATCGCCGCCGGCTCGTTGCGCCGCTCGCAGCAC
GAGCTCAACTATCTGGCGCAGGCGCATTGGCACGGGTTCCACTACCGGCTCGGCGAAATGGTCGGGCTCGATCGCGCCGC
GAAGACGATCACGCTCGCCCCGGTGATCGACGAGGAGGGGCGCGAGATCAATCCCGCCAGCAGCCTCGGCTACGACACGC
TGGTGGTGGCGGTCGGCAGCGTCACCAATGATTTCGGCACGCCCGGAGCAAAGGAGCACGCGGTGCCGCTGGAGACGCCG
GAGCAGGCGACGCGGTTCAACCGCCGCATGGTCAATGCCTGCCTGCGGGCGCAGCATCAACACACGCCGATCGCGCCCGG
TCAGCTCCACGTCGCGATCATCGGCGCCGGCGCCACCGGAACCGAACTCGCCGCCGAACTGCACCACACCGCGCGCGAGA
TCATCGCCTACGGCCTCGACAAGATCGATCCCGAGCACGACCTCAAGATCGTGCTGATCGAGGCCGCCGACCGCATCCTG
CCGGCGCTGCCGCCGCGGATTTCGCAGGCGACGCTGAAGCTGCTGCAGGATCTCGGCGTCGAGGTGCGGACCAAGGCGCG
GGTCGCCGAGGTGCTGGTCGACGGCATCCGTCTCGCCGACGGCGAGGTGGTTCCGTCGGAACTGGTGGTATGGGCCGCCG
GCGTGCGCGCGCCGGATTTCCTCAAGGACATCGACGGGCTCGAGACCAGCCGCATCAATCAGCTGGTGGTCCGGCCGACG
CTGCAGACCAGCCGCGACGACGACGTGTTCGCGCTCGGCGATTGCGCCGCCTGCGCGATTCCCGGCTACGAGAACGGCAT
TCCGCCGCGCGCCCAGGCGGCGCATCAGGAAGCCGAATTCATGCTGGCGCAGATCGACAGGCGGCTGAAGGGCGAAGCGC
TCGGCGGGTTTCAATATCGCGATTTCGGCTCGCTGGTGTCGCTCGGCAAATATTCGACCGTCGGCAGCCTGATGGGCTCG
CTGGTGAGCAAGAGCTTCATGATCGAGGGCTATTTCGCGCGCTTCATGTACAACTCGCTGTACAAGATGCACGAGGCGGC
GTTGTACGGCCGCAGCCGGACGCTGCTCAGCATGTTGTCCGGCGCGACGCGGCCGACGCCGACGGTGAAATTGCATTGA

Upstream 100 bases:

>100_bases
CGCCCGCCCGATCCCGGTACCATTACGGGTGGCGATGAAAGCCGACGTCGCCTGATCCTGTGCGCGGCGTTAGGGCGTTG
CTAGGGAGACCCGGGCTTTG

Downstream 100 bases:

>100_bases
GGTCCGTCGCGCAAGGCGGTTCCGGTGCAGGCCGCCGCGACGACGATCGCGATGGGTCGGTCCGCATCGCGCCGGACACG
AATGCCCGTGGCACGCGGGA

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MLHGTHRRSATLGCIMTETTPHRIVIVGGGAGGLELATALGDKYGKSDNVRVTLVDRSRTHIWKPLLHAIAAGSLRRSQH
ELNYLAQAHWHGFHYRLGEMVGLDRAAKTITLAPVIDEEGREINPASSLGYDTLVVAVGSVTNDFGTPGAKEHAVPLETP
EQATRFNRRMVNACLRAQHQHTPIAPGQLHVAIIGAGATGTELAAELHHTAREIIAYGLDKIDPEHDLKIVLIEAADRIL
PALPPRISQATLKLLQDLGVEVRTKARVAEVLVDGIRLADGEVVPSELVVWAAGVRAPDFLKDIDGLETSRINQLVVRPT
LQTSRDDDVFALGDCAACAIPGYENGIPPRAQAAHQEAEFMLAQIDRRLKGEALGGFQYRDFGSLVSLGKYSTVGSLMGS
LVSKSFMIEGYFARFMYNSLYKMHEAALYGRSRTLLSMLSGATRPTPTVKLH

Sequences:

>Translated_452_residues
MLHGTHRRSATLGCIMTETTPHRIVIVGGGAGGLELATALGDKYGKSDNVRVTLVDRSRTHIWKPLLHAIAAGSLRRSQH
ELNYLAQAHWHGFHYRLGEMVGLDRAAKTITLAPVIDEEGREINPASSLGYDTLVVAVGSVTNDFGTPGAKEHAVPLETP
EQATRFNRRMVNACLRAQHQHTPIAPGQLHVAIIGAGATGTELAAELHHTAREIIAYGLDKIDPEHDLKIVLIEAADRIL
PALPPRISQATLKLLQDLGVEVRTKARVAEVLVDGIRLADGEVVPSELVVWAAGVRAPDFLKDIDGLETSRINQLVVRPT
LQTSRDDDVFALGDCAACAIPGYENGIPPRAQAAHQEAEFMLAQIDRRLKGEALGGFQYRDFGSLVSLGKYSTVGSLMGS
LVSKSFMIEGYFARFMYNSLYKMHEAALYGRSRTLLSMLSGATRPTPTVKLH
>Mature_452_residues
MLHGTHRRSATLGCIMTETTPHRIVIVGGGAGGLELATALGDKYGKSDNVRVTLVDRSRTHIWKPLLHAIAAGSLRRSQH
ELNYLAQAHWHGFHYRLGEMVGLDRAAKTITLAPVIDEEGREINPASSLGYDTLVVAVGSVTNDFGTPGAKEHAVPLETP
EQATRFNRRMVNACLRAQHQHTPIAPGQLHVAIIGAGATGTELAAELHHTAREIIAYGLDKIDPEHDLKIVLIEAADRIL
PALPPRISQATLKLLQDLGVEVRTKARVAEVLVDGIRLADGEVVPSELVVWAAGVRAPDFLKDIDGLETSRINQLVVRPT
LQTSRDDDVFALGDCAACAIPGYENGIPPRAQAAHQEAEFMLAQIDRRLKGEALGGFQYRDFGSLVSLGKYSTVGSLMGS
LVSKSFMIEGYFARFMYNSLYKMHEAALYGRSRTLLSMLSGATRPTPTVKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=438, Percent_Identity=52.0547945205479, Blast_Score=426, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6320118, Length=463, Percent_Identity=26.3498920086393, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6323794, Length=460, Percent_Identity=25.8695652173913, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323515, Length=452, Percent_Identity=24.3362831858407, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 49097; Mature: 49097

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHGTHRRSATLGCIMTETTPHRIVIVGGGAGGLELATALGDKYGKSDNVRVTLVDRSRT
CCCCCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCHH
HIWKPLLHAIAAGSLRRSQHELNYLAQAHWHGFHYRLGEMVGLDRAAKTITLAPVIDEEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHCEEEEEEEECCCC
REINPASSLGYDTLVVAVGSVTNDFGTPGAKEHAVPLETPEQATRFNRRMVNACLRAQHQ
CCCCCHHHCCCCEEEEEECCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
HTPIAPGQLHVAIIGAGATGTELAAELHHTAREIIAYGLDKIDPEHDLKIVLIEAADRIL
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHH
PALPPRISQATLKLLQDLGVEVRTKARVAEVLVDGIRLADGEVVPSELVVWAAGVRAPDF
HCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHEEEECCCCCCHH
LKDIDGLETSRINQLVVRPTLQTSRDDDVFALGDCAACAIPGYENGIPPRAQAAHQEAEF
HHHHCCCCHHHHHHEEEECCCCCCCCCCEEEECCCHHEECCCCCCCCCCCHHHHHHHHHH
MLAQIDRRLKGEALGGFQYRDFGSLVSLGKYSTVGSLMGSLVSKSFMIEGYFARFMYNSL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKMHEAALYGRSRTLLSMLSGATRPTPTVKLH
HHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEC
>Mature Secondary Structure
MLHGTHRRSATLGCIMTETTPHRIVIVGGGAGGLELATALGDKYGKSDNVRVTLVDRSRT
CCCCCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCHH
HIWKPLLHAIAAGSLRRSQHELNYLAQAHWHGFHYRLGEMVGLDRAAKTITLAPVIDEEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHCEEEEEEEECCCC
REINPASSLGYDTLVVAVGSVTNDFGTPGAKEHAVPLETPEQATRFNRRMVNACLRAQHQ
CCCCCHHHCCCCEEEEEECCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
HTPIAPGQLHVAIIGAGATGTELAAELHHTAREIIAYGLDKIDPEHDLKIVLIEAADRIL
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHHHH
PALPPRISQATLKLLQDLGVEVRTKARVAEVLVDGIRLADGEVVPSELVVWAAGVRAPDF
HCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCHHHEEEECCCCCCHH
LKDIDGLETSRINQLVVRPTLQTSRDDDVFALGDCAACAIPGYENGIPPRAQAAHQEAEF
HHHHCCCCHHHHHHEEEECCCCCCCCCCEEEECCCHHEECCCCCCCCCCCHHHHHHHHHH
MLAQIDRRLKGEALGGFQYRDFGSLVSLGKYSTVGSLMGSLVSKSFMIEGYFARFMYNSL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKMHEAALYGRSRTLLSMLSGATRPTPTVKLH
HHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]