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The map label for this gene is ileS [H]

Identifier: 86751289

GI number: 86751289

Start: 4754286

End: 4757450

Strand: Reverse

Name: ileS [H]

Synonym: RPB_4182

Alternate gene names: 86751289

Gene position: 4757450-4754286 (Counterclockwise)

Preceding gene: 86751292

Following gene: 86751288

Centisome position: 89.23

GC content: 65.12

Gene sequence:

>3165_bases
ATGACCGAAAAGCCCGCGAAATCCGACGCCGCCCAGAGCGGTACCGACTATTCCAAGACCCTGTACCTGCCGCAGACGGA
GTTTCCGATGCGCGCCGGGCTGCCGGCCCGCGAGCCGGAATTGCTCAAGCGCTGGGAGGAGATCGACCTCTACGGCAAGT
TGCGCGAGAGCGCGCGCGGCCGTGCCAAATTCGTGCTACACGACGGCCCGCCTTACGCCAACGGCAACATCCATATCGGC
CATGCGCTGAACAAGATCCTCAAGGACGTCGTCACCAAGAGCCAGCAGATGCTCGGGTTCGACTCCAACTACGTGCCGGG
CTGGGACTGCCACGGCCTGCCGATCGAATGGAAGATCGAGGAGGAGAATTACCGCTCCAAGGGCAAGCCGAAGCCGAACT
TCAAGGATTCGACCGCGATGGTCGCGTTCCGCAAGGAATGCCGCGCCTACGCGCAGAAGTGGCTCGACGTGCAGCGCGCG
GAATTCAAGCGCCTCGGCATCGTCGGCGACTGGGATCATCCCTACGCCACGATGGACTACTTCGCCGAGGCCCAGATCGC
CCGCGAACTGATGAAATTCGCCGCCAACGGCACACTGTATCGCGGCTCCAAGCCGGTGATGTGGAGCGTGGTGGAGAAGA
CCGCGCTGGCCGAGGCTGAGGTCGAGTACGAGGACCACACCAGCGATACGGTGTGGGTGAAGTTTTCGGTAGTCGCGACA
GGTAGGCCAGCTGAACGTTACTCTCGGCTTTCTCCCAATATGACTAGCGACGGAGAGGGGGGGCTCACTGCTAAGCGCGG
AGGTCAAGAGGCTGAATCGATCAAGAAGTCCATCGGCGAGAGCCTCGGTGCTTGGGATAACCTTACTGAGCGCCTTGAGA
CTGGTGAAGGCTTCTCGGTTGTCATCTGGACAACCACGCCGTGGACGCTGCCGGGCAACCGCGCAATCAGCTTCTCGTCC
AAAATCGGCTATGGCCTGTACAAGGTCACCGATGCGCCGGCTGACAACTGGGCTAAGACGGGCGACCTGCTTGTCCTCGC
CGATGCCTTAGCCGAAAGCGTCTTCAAGCAGTCGCGCGTGGTCGCTTTCGAGAAGGTAGCGGCCGTGCCTGCCGACGTTC
TTGAGGCGATGCAATGTGCACATCCGCTACGCGGCCTCGCCGGCGGCTATGAGTTCACTGTCCCGCTGCTCGACGGCGAC
CACGTCACCGACGACACTGGCACCGGCTTCGTTCACACCGCGCCGGGCCATGGCCGCGAGGATTTCGATATCTGGATGCA
CAATGCCCGGGCACTCGAAGCGCGCGGCATCGCCTCGACGATTCCCTACACCGTCGACGAGAACGGCGCGCTGACCGATC
ACGCGCCCGGCTTCACCGGCAAGCGGGTGATCAACGACAAGGGCGAGAAGGGCGACGCCAACGAGGCGGTGATCCAGGCC
CTGATCGCGCGCGGCATGCTGCTGGCGCGCGGCAAGCTCAAGCATCAATATCCGCATTCGTGGCGCTCGAAGAAGCCGGT
GATCTTCCGCAACACGCCGCAATGGTTCATCGCGATGGACAAGGACATCGCGGATAGCGGCGACGCGAAGCAAGGCGATA
CGCTGCGCGCCCGCGCGCTGCAGGCGATCTCGGTCACGCAGTGGGTGCCGCCCGCCGGGCAGAACCGCATCACCGGCATG
ATTTCAGGCCGGCCCGACTGGGTGATCTCGCGGCAGCGCGCCTGGGGCGTGCCGATTGCGGTGTTCGTGCGCGAGACCGG
CGACGGCTCTGCCGAGATCCTGGTCGACGACGCCGTCAATGCCCGCATCGCCGAGGCGTTCGAGGCCGAAGGCGCCGACG
CCTGGTACGAGGAGGGCGCCCGCGAGCGCTTTCTGGGCTCCCGCGCCAACGAGGAGTGGCAGAAGGTCGACGACATCTGC
GACGTCTGGTTCGACTCCGGCTCCACCCACGCCTTCGTGCTGGAAGATCCGGTGCACTTCCCCGGCCTCGCCGGCATCCG
CCGCAAGGTCGACGGCGGCGCCGACACCGTGATGTATCTCGAAGGCTCCGACCAGCATCGTGGCTGGTTTCATTCGTCGC
TGCTGGAGAGTTGCGGCACCCGCGGCCGCGCGCCCTACGATGTCGTGCTGACGCACGGCTTCACGCTCGACGAGCAGGGC
CGCAAGATGTCGAAATCGCTCGGCAACACCACCGATCCGGCCAAGGTGATCGCGTCGTCGGGCGCCGACATCCTGCGGCT
GTGGGTGTGCGCCACCGACTATGCCGACGACCAGCGCATCGGCCCCGAGATCCTCAAGAACGTGGTCGAGACCTATCGCA
AGCTGCGCAATTCGATCCGCTGGATGCTCGGCACGCTGCATCACTACAAGCGCGACGAGGCGGTGGCGTTCGCCGACATG
CCGGAGCTGGAGCGGCTGATGCTGCATCAGCTCGCCGAGCAGAGCGCCATCGTGCGCGCCGCCTATGCGGAGTTCGACTA
CAAGACCGTGGTCGCCTCGCTCGCCGCCTTCATGAACACCGAATTGTCGGCATTCTATTTCGACATCCGCAAGGACACGC
TGTATTGCGATCCGCCGTCGTCGCTGGCCCGCAAGGCGGCGCTGACGGCGATCGACATCATCTGCGACGCGATCCTGAAA
TGGCTGGCGCCGGTCTTGTCCTTCACCACCGACGAAGCCTGGAGCCTTTATCGGCCGGGCGCTGAGCCGAGCGTGCATCT
GACGCTGTTCCCGCTCGACCTCGGCACCTATCGCAACGACGAACTGGCGAAGAAGTGGGAGACCATCCGCAGCGTCCGCC
GCGTCGTCACCGGCGCGCTGGAGCTGGAGCGCGCCGCCAAGCGGATCGGCTCGTCGCTGGAAGCCTCGCCGGTGATCTAC
CTCGCCGACCGGCCGCTGCTGGCGACGGTGTTCGACACCGACCTCGCCGAGATCTGCATCACCTCGAACTACGAGATCCG
CGAAGGCGACGCGCCGGAGGGTGCGTTCCGGTTGGACAACGTCACCGGCGTCGCGGTGGTGGTCGAGCGCGCGCAGGGCA
CCAAATGCGCCCGCTCCTGGAAGATCCTGTCCTCCGTCGGCAGCGACCCCGACTATCCCGACGTCTCCCCCCGCGACGCC
AAGGCGCTGCGCGAGTGGAAGGCGTTGGGCGTGGCGGCGTCTTGA

Upstream 100 bases:

>100_bases
TTGCGCGGCGACCCTCGATCGGCCCAAGCCGGTGAAGATTTAGCCCTCCGCCGGTTCGATCGGGTTTCCCCGGCCGGCCA
AAACCGCTATTCACGCCGCC

Downstream 100 bases:

>100_bases
GCGCGATGCGGTCCACCTCACGTCCGTCATGGCCGGGCTCGTCCCCGCCATCCACGGCCGCGGGCACGGTGCTCGTTTCG
TGGATGCCCGGGTCAAGCCC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS [H]

Number of amino acids: Translated: 1054; Mature: 1053

Protein sequence:

>1054_residues
MTEKPAKSDAAQSGTDYSKTLYLPQTEFPMRAGLPAREPELLKRWEEIDLYGKLRESARGRAKFVLHDGPPYANGNIHIG
HALNKILKDVVTKSQQMLGFDSNYVPGWDCHGLPIEWKIEEENYRSKGKPKPNFKDSTAMVAFRKECRAYAQKWLDVQRA
EFKRLGIVGDWDHPYATMDYFAEAQIARELMKFAANGTLYRGSKPVMWSVVEKTALAEAEVEYEDHTSDTVWVKFSVVAT
GRPAERYSRLSPNMTSDGEGGLTAKRGGQEAESIKKSIGESLGAWDNLTERLETGEGFSVVIWTTTPWTLPGNRAISFSS
KIGYGLYKVTDAPADNWAKTGDLLVLADALAESVFKQSRVVAFEKVAAVPADVLEAMQCAHPLRGLAGGYEFTVPLLDGD
HVTDDTGTGFVHTAPGHGREDFDIWMHNARALEARGIASTIPYTVDENGALTDHAPGFTGKRVINDKGEKGDANEAVIQA
LIARGMLLARGKLKHQYPHSWRSKKPVIFRNTPQWFIAMDKDIADSGDAKQGDTLRARALQAISVTQWVPPAGQNRITGM
ISGRPDWVISRQRAWGVPIAVFVRETGDGSAEILVDDAVNARIAEAFEAEGADAWYEEGARERFLGSRANEEWQKVDDIC
DVWFDSGSTHAFVLEDPVHFPGLAGIRRKVDGGADTVMYLEGSDQHRGWFHSSLLESCGTRGRAPYDVVLTHGFTLDEQG
RKMSKSLGNTTDPAKVIASSGADILRLWVCATDYADDQRIGPEILKNVVETYRKLRNSIRWMLGTLHHYKRDEAVAFADM
PELERLMLHQLAEQSAIVRAAYAEFDYKTVVASLAAFMNTELSAFYFDIRKDTLYCDPPSSLARKAALTAIDIICDAILK
WLAPVLSFTTDEAWSLYRPGAEPSVHLTLFPLDLGTYRNDELAKKWETIRSVRRVVTGALELERAAKRIGSSLEASPVIY
LADRPLLATVFDTDLAEICITSNYEIREGDAPEGAFRLDNVTGVAVVVERAQGTKCARSWKILSSVGSDPDYPDVSPRDA
KALREWKALGVAAS

Sequences:

>Translated_1054_residues
MTEKPAKSDAAQSGTDYSKTLYLPQTEFPMRAGLPAREPELLKRWEEIDLYGKLRESARGRAKFVLHDGPPYANGNIHIG
HALNKILKDVVTKSQQMLGFDSNYVPGWDCHGLPIEWKIEEENYRSKGKPKPNFKDSTAMVAFRKECRAYAQKWLDVQRA
EFKRLGIVGDWDHPYATMDYFAEAQIARELMKFAANGTLYRGSKPVMWSVVEKTALAEAEVEYEDHTSDTVWVKFSVVAT
GRPAERYSRLSPNMTSDGEGGLTAKRGGQEAESIKKSIGESLGAWDNLTERLETGEGFSVVIWTTTPWTLPGNRAISFSS
KIGYGLYKVTDAPADNWAKTGDLLVLADALAESVFKQSRVVAFEKVAAVPADVLEAMQCAHPLRGLAGGYEFTVPLLDGD
HVTDDTGTGFVHTAPGHGREDFDIWMHNARALEARGIASTIPYTVDENGALTDHAPGFTGKRVINDKGEKGDANEAVIQA
LIARGMLLARGKLKHQYPHSWRSKKPVIFRNTPQWFIAMDKDIADSGDAKQGDTLRARALQAISVTQWVPPAGQNRITGM
ISGRPDWVISRQRAWGVPIAVFVRETGDGSAEILVDDAVNARIAEAFEAEGADAWYEEGARERFLGSRANEEWQKVDDIC
DVWFDSGSTHAFVLEDPVHFPGLAGIRRKVDGGADTVMYLEGSDQHRGWFHSSLLESCGTRGRAPYDVVLTHGFTLDEQG
RKMSKSLGNTTDPAKVIASSGADILRLWVCATDYADDQRIGPEILKNVVETYRKLRNSIRWMLGTLHHYKRDEAVAFADM
PELERLMLHQLAEQSAIVRAAYAEFDYKTVVASLAAFMNTELSAFYFDIRKDTLYCDPPSSLARKAALTAIDIICDAILK
WLAPVLSFTTDEAWSLYRPGAEPSVHLTLFPLDLGTYRNDELAKKWETIRSVRRVVTGALELERAAKRIGSSLEASPVIY
LADRPLLATVFDTDLAEICITSNYEIREGDAPEGAFRLDNVTGVAVVVERAQGTKCARSWKILSSVGSDPDYPDVSPRDA
KALREWKALGVAAS
>Mature_1053_residues
TEKPAKSDAAQSGTDYSKTLYLPQTEFPMRAGLPAREPELLKRWEEIDLYGKLRESARGRAKFVLHDGPPYANGNIHIGH
ALNKILKDVVTKSQQMLGFDSNYVPGWDCHGLPIEWKIEEENYRSKGKPKPNFKDSTAMVAFRKECRAYAQKWLDVQRAE
FKRLGIVGDWDHPYATMDYFAEAQIARELMKFAANGTLYRGSKPVMWSVVEKTALAEAEVEYEDHTSDTVWVKFSVVATG
RPAERYSRLSPNMTSDGEGGLTAKRGGQEAESIKKSIGESLGAWDNLTERLETGEGFSVVIWTTTPWTLPGNRAISFSSK
IGYGLYKVTDAPADNWAKTGDLLVLADALAESVFKQSRVVAFEKVAAVPADVLEAMQCAHPLRGLAGGYEFTVPLLDGDH
VTDDTGTGFVHTAPGHGREDFDIWMHNARALEARGIASTIPYTVDENGALTDHAPGFTGKRVINDKGEKGDANEAVIQAL
IARGMLLARGKLKHQYPHSWRSKKPVIFRNTPQWFIAMDKDIADSGDAKQGDTLRARALQAISVTQWVPPAGQNRITGMI
SGRPDWVISRQRAWGVPIAVFVRETGDGSAEILVDDAVNARIAEAFEAEGADAWYEEGARERFLGSRANEEWQKVDDICD
VWFDSGSTHAFVLEDPVHFPGLAGIRRKVDGGADTVMYLEGSDQHRGWFHSSLLESCGTRGRAPYDVVLTHGFTLDEQGR
KMSKSLGNTTDPAKVIASSGADILRLWVCATDYADDQRIGPEILKNVVETYRKLRNSIRWMLGTLHHYKRDEAVAFADMP
ELERLMLHQLAEQSAIVRAAYAEFDYKTVVASLAAFMNTELSAFYFDIRKDTLYCDPPSSLARKAALTAIDIICDAILKW
LAPVLSFTTDEAWSLYRPGAEPSVHLTLFPLDLGTYRNDELAKKWETIRSVRRVVTGALELERAAKRIGSSLEASPVIYL
ADRPLLATVFDTDLAEICITSNYEIREGDAPEGAFRLDNVTGVAVVVERAQGTKCARSWKILSSVGSDPDYPDVSPRDAK
ALREWKALGVAAS

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI46852147, Length=900, Percent_Identity=34.7777777777778, Blast_Score=495, Evalue=1e-140,
Organism=Homo sapiens, GI94721239, Length=916, Percent_Identity=25, Blast_Score=265, Evalue=2e-70,
Organism=Homo sapiens, GI94721241, Length=916, Percent_Identity=25, Blast_Score=265, Evalue=2e-70,
Organism=Homo sapiens, GI5454158, Length=643, Percent_Identity=24.7278382581649, Blast_Score=101, Evalue=5e-21,
Organism=Homo sapiens, GI268370297, Length=630, Percent_Identity=21.5873015873016, Blast_Score=77, Evalue=7e-14,
Organism=Homo sapiens, GI268370293, Length=630, Percent_Identity=21.5873015873016, Blast_Score=77, Evalue=8e-14,
Organism=Homo sapiens, GI268370295, Length=630, Percent_Identity=21.7460317460317, Blast_Score=77, Evalue=1e-13,
Organism=Escherichia coli, GI2367096, Length=1035, Percent_Identity=40.4830917874396, Blast_Score=703, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=978, Percent_Identity=30.6748466257669, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17541896, Length=927, Percent_Identity=25.4584681769148, Blast_Score=244, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17510661, Length=626, Percent_Identity=22.2044728434505, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI72001587, Length=161, Percent_Identity=27.3291925465839, Blast_Score=68, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325217, Length=1055, Percent_Identity=31.3744075829384, Blast_Score=462, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6319395, Length=883, Percent_Identity=25.4813137032843, Blast_Score=259, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6321531, Length=550, Percent_Identity=24.3636363636364, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281366294, Length=906, Percent_Identity=33.112582781457, Blast_Score=429, Evalue=1e-120,
Organism=Drosophila melanogaster, GI28574730, Length=942, Percent_Identity=25.0530785562633, Blast_Score=255, Evalue=9e-68,
Organism=Drosophila melanogaster, GI24668547, Length=942, Percent_Identity=25.0530785562633, Blast_Score=255, Evalue=9e-68,
Organism=Drosophila melanogaster, GI24668543, Length=942, Percent_Identity=25.0530785562633, Blast_Score=255, Evalue=9e-68,
Organism=Drosophila melanogaster, GI17864482, Length=665, Percent_Identity=22.2556390977444, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24653289, Length=665, Percent_Identity=22.2556390977444, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355675, Length=637, Percent_Identity=21.0361067503925, Blast_Score=85, Evalue=3e-16,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 116761; Mature: 116630

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKPAKSDAAQSGTDYSKTLYLPQTEFPMRAGLPAREPELLKRWEEIDLYGKLRESARG
CCCCCCCCCHHCCCCCCCEEEECCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
RAKFVLHDGPPYANGNIHIGHALNKILKDVVTKSQQMLGFDSNYVPGWDCHGLPIEWKIE
CEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEC
EENYRSKGKPKPNFKDSTAMVAFRKECRAYAQKWLDVQRAEFKRLGIVGDWDHPYATMDY
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
FAEAQIARELMKFAANGTLYRGSKPVMWSVVEKTALAEAEVEYEDHTSDTVWVKFSVVAT
HHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEC
GRPAERYSRLSPNMTSDGEGGLTAKRGGQEAESIKKSIGESLGAWDNLTERLETGEGFSV
CCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEE
VIWTTTPWTLPGNRAISFSSKIGYGLYKVTDAPADNWAKTGDLLVLADALAESVFKQSRV
EEEECCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
VAFEKVAAVPADVLEAMQCAHPLRGLAGGYEFTVPLLDGDHVTDDTGTGFVHTAPGHGRE
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCCC
DFDIWMHNARALEARGIASTIPYTVDENGALTDHAPGFTGKRVINDKGEKGDANEAVIQA
CHHHHHCCCHHHHHCCCHHHCCEEECCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHH
LIARGMLLARGKLKHQYPHSWRSKKPVIFRNTPQWFIAMDKDIADSGDAKQGDTLRARAL
HHHHCHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHH
QAISVTQWVPPAGQNRITGMISGRPDWVISRQRAWGVPIAVFVRETGDGSAEILVDDAVN
HHHHHHHCCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEEEEEECCCCCEEEEEECCCC
ARIAEAFEAEGADAWYEEGARERFLGSRANEEWQKVDDICDVWFDSGSTHAFVLEDPVHF
HHHHHHHHCCCCHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
PGLAGIRRKVDGGADTVMYLEGSDQHRGWFHSSLLESCGTRGRAPYDVVLTHGFTLDEQG
CCHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHH
RKMSKSLGNTTDPAKVIASSGADILRLWVCATDYADDQRIGPEILKNVVETYRKLRNSIR
HHHHHHCCCCCCHHHHHHCCCCHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
WMLGTLHHYKRDEAVAFADMPELERLMLHQLAEQSAIVRAAYAEFDYKTVVASLAAFMNT
HHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ELSAFYFDIRKDTLYCDPPSSLARKAALTAIDIICDAILKWLAPVLSFTTDEAWSLYRPG
CCEEEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC
AEPSVHLTLFPLDLGTYRNDELAKKWETIRSVRRVVTGALELERAAKRIGSSLEASPVIY
CCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LADRPLLATVFDTDLAEICITSNYEIREGDAPEGAFRLDNVTGVAVVVERAQGTKCARSW
EECCCEEEEHHHCCHHHHEECCCCEEECCCCCCCCEEECCCCEEEEEEECCCCCHHHHHH
KILSSVGSDPDYPDVSPRDAKALREWKALGVAAS
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TEKPAKSDAAQSGTDYSKTLYLPQTEFPMRAGLPAREPELLKRWEEIDLYGKLRESARG
CCCCCCCCHHCCCCCCCEEEECCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
RAKFVLHDGPPYANGNIHIGHALNKILKDVVTKSQQMLGFDSNYVPGWDCHGLPIEWKIE
CEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEC
EENYRSKGKPKPNFKDSTAMVAFRKECRAYAQKWLDVQRAEFKRLGIVGDWDHPYATMDY
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
FAEAQIARELMKFAANGTLYRGSKPVMWSVVEKTALAEAEVEYEDHTSDTVWVKFSVVAT
HHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEC
GRPAERYSRLSPNMTSDGEGGLTAKRGGQEAESIKKSIGESLGAWDNLTERLETGEGFSV
CCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEE
VIWTTTPWTLPGNRAISFSSKIGYGLYKVTDAPADNWAKTGDLLVLADALAESVFKQSRV
EEEECCCCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
VAFEKVAAVPADVLEAMQCAHPLRGLAGGYEFTVPLLDGDHVTDDTGTGFVHTAPGHGRE
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCCC
DFDIWMHNARALEARGIASTIPYTVDENGALTDHAPGFTGKRVINDKGEKGDANEAVIQA
CHHHHHCCCHHHHHCCCHHHCCEEECCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHH
LIARGMLLARGKLKHQYPHSWRSKKPVIFRNTPQWFIAMDKDIADSGDAKQGDTLRARAL
HHHHCHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHH
QAISVTQWVPPAGQNRITGMISGRPDWVISRQRAWGVPIAVFVRETGDGSAEILVDDAVN
HHHHHHHCCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEEEEEECCCCCEEEEEECCCC
ARIAEAFEAEGADAWYEEGARERFLGSRANEEWQKVDDICDVWFDSGSTHAFVLEDPVHF
HHHHHHHHCCCCHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
PGLAGIRRKVDGGADTVMYLEGSDQHRGWFHSSLLESCGTRGRAPYDVVLTHGFTLDEQG
CCHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHH
RKMSKSLGNTTDPAKVIASSGADILRLWVCATDYADDQRIGPEILKNVVETYRKLRNSIR
HHHHHHCCCCCCHHHHHHCCCCHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
WMLGTLHHYKRDEAVAFADMPELERLMLHQLAEQSAIVRAAYAEFDYKTVVASLAAFMNT
HHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ELSAFYFDIRKDTLYCDPPSSLARKAALTAIDIICDAILKWLAPVLSFTTDEAWSLYRPG
CCEEEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCC
AEPSVHLTLFPLDLGTYRNDELAKKWETIRSVRRVVTGALELERAAKRIGSSLEASPVIY
CCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LADRPLLATVFDTDLAEICITSNYEIREGDAPEGAFRLDNVTGVAVVVERAQGTKCARSW
EECCCEEEEHHHCCHHHHEECCCCEEECCCCCCCCEEECCCCEEEEEEECCCCCHHHHHH
KILSSVGSDPDYPDVSPRDAKALREWKALGVAAS
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA