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The map label for this gene is fabH [H]

Identifier: 86751230

GI number: 86751230

Start: 4694468

End: 4695595

Strand: Direct

Name: fabH [H]

Synonym: RPB_4123

Alternate gene names: 86751230

Gene position: 4694468-4695595 (Clockwise)

Preceding gene: 86751227

Following gene: 86751240

Centisome position: 88.05

GC content: 65.6

Gene sequence:

>1128_bases
GTGCGCCCTGCCGTCATTGCCGCGACCGGCCTCTACACCCCGCCCGACAGTATTTCGAATGTCGAGCTGGTGCAGGCGTT
CAACACCTATGTGGCGAACTTCAACGCAGCCAACCAGGCGGCGATCGCCGCCGGGCAGATCGAGCCGCTGCTGCCGTCGT
CGCCGGAATTCATCGAGAAGGCGTCCGGCATCAAGTCGCGCTACGTGGTGGCGAAAGCCGGCATCCTCGATCCGGAGCTG
ATGCGGCCGGTGATCCCGGAGCGGCCGAACGAACAGGTCTCGGTGCTGGCCGAGATCGCCGTGAAGGCCGCCGACGAGGC
GCTGGCGCGCTGGGGCAAGCCGCGCGAGCGGATCGGCGCGGTGCTGTGCGCCTGCTCCAACATGCAGCGCGCCTACCCCG
CAATGGCGGTCGAGGTGCAGGACGCGCTCGGCCTCGGCGGCTTCGCCTTCGACATGAACGTGGCCTGCTCGTCCGCGACC
TTCGGCATCAAGACCGCGGCGGATTTCGTCGCCACCGGCTCGGCCGACGCGGTGCTGATGGTCAATCCCGAGATCTGCTC
CGGGCATCTCAATTTCCGCGACCGCGACAGTCACTTCATTTTCGGCGACGTCGCCACCGCGGTGATCGTCGAGCGCGCCG
ACGAAGCGCAAGATGGTGAACGGGCCGGCTGGGCGATCCTCGGCACAAGGCTGAAGACGCAGTTCTCCAACAACATCCGC
AACAATTCCGGATTCCTCAACCGCGCCTGGCCGGAAGGCCGCGACCTCACCGACAAGCTGTTCGTGCAGCAGGGCCGCAA
GGTGTTCAAGGAAGTGGTGCCGATGGTCTCCGACATGATCATCGACCACGCCGCCGAACTCGGCATCGATCCGCACGCGC
TGAAGCGGATGTGGCTGCACCAAGCCAACATCAACATGAACGAGATCATCGGCCGCAAGGTGCTGGGCCGCGATCCGACG
CGCGAAGAGAACGTCATCATCCTCGACAGCTACGCCAACACCTCGTCGGCCGGCTCGATCATCGCCTTCCACACCGCCTC
GGACGATCTGGCGCAAGGCGACCTCGGCCTGATCTGCTCGTTCGGCGCCGGATATTCGGCCGGCACGGTGTTCGTGCAGA
AGCGCTGA

Upstream 100 bases:

>100_bases
GTCAAAGCCGACGCCGGGCAATCGGCGTGGGATACCGCGGGGCGCGGCGGATCGCCAACGGCCGGCGGTCCTCACTCAGC
CAATCCGACCGGAGCTTTCC

Downstream 100 bases:

>100_bases
GCAGCGCCGGCGCGCGCGGCGGACCGCTACCGGAACTCACGCGCGCGCCGATTTGATCTTCCTGATCTCGCGCATCTGCG
CGGAGAAATCCTCCAGCGCG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MRPAVIAATGLYTPPDSISNVELVQAFNTYVANFNAANQAAIAAGQIEPLLPSSPEFIEKASGIKSRYVVAKAGILDPEL
MRPVIPERPNEQVSVLAEIAVKAADEALARWGKPRERIGAVLCACSNMQRAYPAMAVEVQDALGLGGFAFDMNVACSSAT
FGIKTAADFVATGSADAVLMVNPEICSGHLNFRDRDSHFIFGDVATAVIVERADEAQDGERAGWAILGTRLKTQFSNNIR
NNSGFLNRAWPEGRDLTDKLFVQQGRKVFKEVVPMVSDMIIDHAAELGIDPHALKRMWLHQANINMNEIIGRKVLGRDPT
REENVIILDSYANTSSAGSIIAFHTASDDLAQGDLGLICSFGAGYSAGTVFVQKR

Sequences:

>Translated_375_residues
MRPAVIAATGLYTPPDSISNVELVQAFNTYVANFNAANQAAIAAGQIEPLLPSSPEFIEKASGIKSRYVVAKAGILDPEL
MRPVIPERPNEQVSVLAEIAVKAADEALARWGKPRERIGAVLCACSNMQRAYPAMAVEVQDALGLGGFAFDMNVACSSAT
FGIKTAADFVATGSADAVLMVNPEICSGHLNFRDRDSHFIFGDVATAVIVERADEAQDGERAGWAILGTRLKTQFSNNIR
NNSGFLNRAWPEGRDLTDKLFVQQGRKVFKEVVPMVSDMIIDHAAELGIDPHALKRMWLHQANINMNEIIGRKVLGRDPT
REENVIILDSYANTSSAGSIIAFHTASDDLAQGDLGLICSFGAGYSAGTVFVQKR
>Mature_375_residues
MRPAVIAATGLYTPPDSISNVELVQAFNTYVANFNAANQAAIAAGQIEPLLPSSPEFIEKASGIKSRYVVAKAGILDPEL
MRPVIPERPNEQVSVLAEIAVKAADEALARWGKPRERIGAVLCACSNMQRAYPAMAVEVQDALGLGGFAFDMNVACSSAT
FGIKTAADFVATGSADAVLMVNPEICSGHLNFRDRDSHFIFGDVATAVIVERADEAQDGERAGWAILGTRLKTQFSNNIR
NNSGFLNRAWPEGRDLTDKLFVQQGRKVFKEVVPMVSDMIIDHAAELGIDPHALKRMWLHQANINMNEIIGRKVLGRDPT
REENVIILDSYANTSSAGSIIAFHTASDDLAQGDLGLICSFGAGYSAGTVFVQKR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=330, Percent_Identity=26.3636363636364, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 40423; Mature: 40423

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAVIAATGLYTPPDSISNVELVQAFNTYVANFNAANQAAIAAGQIEPLLPSSPEFIEK
CCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHH
ASGIKSRYVVAKAGILDPELMRPVIPERPNEQVSVLAEIAVKAADEALARWGKPRERIGA
HCCCCCEEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VLCACSNMQRAYPAMAVEVQDALGLGGFAFDMNVACSSATFGIKTAADFVATGSADAVLM
HHHHHHCHHHHCCCEEEEEHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEE
VNPEICSGHLNFRDRDSHFIFGDVATAVIVERADEAQDGERAGWAILGTRLKTQFSNNIR
ECCHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCC
NNSGFLNRAWPEGRDLTDKLFVQQGRKVFKEVVPMVSDMIIDHAAELGIDPHALKRMWLH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QANINMNEIIGRKVLGRDPTREENVIILDSYANTSSAGSIIAFHTASDDLAQGDLGLICS
HCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEEEEE
FGAGYSAGTVFVQKR
CCCCCCCCEEEEEEC
>Mature Secondary Structure
MRPAVIAATGLYTPPDSISNVELVQAFNTYVANFNAANQAAIAAGQIEPLLPSSPEFIEK
CCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCHHHHHH
ASGIKSRYVVAKAGILDPELMRPVIPERPNEQVSVLAEIAVKAADEALARWGKPRERIGA
HCCCCCEEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VLCACSNMQRAYPAMAVEVQDALGLGGFAFDMNVACSSATFGIKTAADFVATGSADAVLM
HHHHHHCHHHHCCCEEEEEHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEE
VNPEICSGHLNFRDRDSHFIFGDVATAVIVERADEAQDGERAGWAILGTRLKTQFSNNIR
ECCHHHCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCC
NNSGFLNRAWPEGRDLTDKLFVQQGRKVFKEVVPMVSDMIIDHAAELGIDPHALKRMWLH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QANINMNEIIGRKVLGRDPTREENVIILDSYANTSSAGSIIAFHTASDDLAQGDLGLICS
HCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEEEEE
FGAGYSAGTVFVQKR
CCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA